Stanford University School of Medicine
Research Scientist in CRISPR Genomics, Engreitz Lab (2 Year Fixed Term)
Stanford University School of Medicine, Stanford, California, United States, 94305
Overview
The Laboratory of Jesse Engreitz (Dept of Genetics, BASE Initiative) is seeking a Research Scientist in CRISPR Genomics (Life Science Research Professional 3) to lead large-scale data production projects to understand the genetic basis of heart diseases. The Engreitz Lab is located in the Biomedical Innovations Building on the main campus at Stanford University and is a member of the BASE Initiative in the Betty Irene Moore Children’s Heart Center. We are looking for a creative and passionate Research Scientist (PhD-level) to lead the next phase of our efforts to systematically perturb the genome to understand genome function and phenotype. The ideal candidate would lead independent projects, design and supervise large-scale CRISPR data generation projects, manage collaborations between the Engreitz Lab and NIH-led consortia, and play a leading role in writing publications and grants. The Engreitz Lab provides a dynamic, interdisciplinary workplace with unique access to cutting edge technologies and scientific thought, with the potential for widespread recognition of scientific contributions. We value a diversity of values, backgrounds, and approaches to solving problems. Position type: 2-Year Fixed-Term, with extension possible. For information and recent work, see https://www.engreitzlab.org and https://med.stanford.edu/base.html.
Duties Include
Make fundamental discoveries about gene regulation and the genetics of cardiovascular disease Together with PI and other lab members, design and execute scientific projects Collect comprehensive perturbation datasets to inform genome function and enable training predictive models Develop and apply strategies to study enhancers and genes in human cells and mouse models Evaluate and recommend new emerging technologies, approaches, and problems Supervise, train, and collaborate with other lab members in experimental techniques, scientific design, and other skills Design and lead independent projects Collaborate with a team of experimentalists and computational biologists Create scientifically rigorous visualizations, communications, and presentations of results Contribute to generation of protocols, publications, and intellectual property Other duties may also be assigned.
Qualifications & Experience (required)
Ph.D. in Genetics, Biology, Biochemistry, Biophysics, Bioengineering, Developmental Biology, or related life science field is preferred. Highly motivated candidates of all levels are encouraged to apply. Hands-on experience in cellular genomics, molecular biology, and technology development Experience with quantitative data analysis Experience with CRISPR targeting ES/iPS cells and/or single-cell technologies a plus Experience in multidisciplinary collaborations, management, and/or supervision Curiosity in research and creativity in problem-solving Strong interpersonal and collaboration skills; outstanding verbal and written communication abilities Ability to adapt to and effectively manage changes in a fast paced and dynamic environment A passion for science and sense of urgency to find new medicines to benefit patients
Education & Experience (required)
Bachelor's degree in related scientific field and four years of relevant work experience; or Master’s degree in a related scientific field and two years relevant experience; or PhD in related science field.
Knowledge, Skills And Abilities (required)
Comprehensive understanding of scientific principles Expert level knowledge and skills in field of science related to the research project General computer skills and experience with databases and scientific applications Strong analytical skills and excellent judgment Ability to work under deadlines with general guidance Excellent organizational skills and demonstrated ability to complete detailed work accurately Developing project management skills
Certifications & Licenses
None.
Physicial Requirements
Frequently stand, walk, twist, bend, stoop, squat, grasp lightly, use fine manipulation, grasp forcefully, perform desk-based computer tasks, use telephone, write by hand, lift, carry, push and pull objects Occasionally sit, kneel, crawl, reach and work above shoulders Rarely climb, scrub, sweep, mop, chop and operate hand and foot controls Must have correctible vision to perform duties Ability to move on hard surfaces for up to eight hours Ability to lift heavy objects weighing up to 50 pounds Position may require repetitive motion Reasonable accommodation available for applicants with disabilities
Working Conditions
May require working in close proximity to blood borne pathogens May require work in environments with animals used for teaching and research May work with hazardous materials and/or infectious diseases; PPE may be required May require extended or unusual work hours based on research requirements
Work Standards
Interpersonal Skills: ability to work well with Stanford colleagues, clients, and external organizations Promote Culture of Safety: commitment to safety and reporting concerns Comply with University policies and procedures
The expected pay range for this position is $93,062 to $111,670 per annum. The pay offered will be determined based on qualifications, responsibilities, budget, equity, location, and market pay.
Stanford is an equal employment opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law.
Applications: Submit via the Stanford web portal; email CV and cover letter to Prof. Jesse Engreitz (engreitz@stanford.edu).
#J-18808-Ljbffr
The Laboratory of Jesse Engreitz (Dept of Genetics, BASE Initiative) is seeking a Research Scientist in CRISPR Genomics (Life Science Research Professional 3) to lead large-scale data production projects to understand the genetic basis of heart diseases. The Engreitz Lab is located in the Biomedical Innovations Building on the main campus at Stanford University and is a member of the BASE Initiative in the Betty Irene Moore Children’s Heart Center. We are looking for a creative and passionate Research Scientist (PhD-level) to lead the next phase of our efforts to systematically perturb the genome to understand genome function and phenotype. The ideal candidate would lead independent projects, design and supervise large-scale CRISPR data generation projects, manage collaborations between the Engreitz Lab and NIH-led consortia, and play a leading role in writing publications and grants. The Engreitz Lab provides a dynamic, interdisciplinary workplace with unique access to cutting edge technologies and scientific thought, with the potential for widespread recognition of scientific contributions. We value a diversity of values, backgrounds, and approaches to solving problems. Position type: 2-Year Fixed-Term, with extension possible. For information and recent work, see https://www.engreitzlab.org and https://med.stanford.edu/base.html.
Duties Include
Make fundamental discoveries about gene regulation and the genetics of cardiovascular disease Together with PI and other lab members, design and execute scientific projects Collect comprehensive perturbation datasets to inform genome function and enable training predictive models Develop and apply strategies to study enhancers and genes in human cells and mouse models Evaluate and recommend new emerging technologies, approaches, and problems Supervise, train, and collaborate with other lab members in experimental techniques, scientific design, and other skills Design and lead independent projects Collaborate with a team of experimentalists and computational biologists Create scientifically rigorous visualizations, communications, and presentations of results Contribute to generation of protocols, publications, and intellectual property Other duties may also be assigned.
Qualifications & Experience (required)
Ph.D. in Genetics, Biology, Biochemistry, Biophysics, Bioengineering, Developmental Biology, or related life science field is preferred. Highly motivated candidates of all levels are encouraged to apply. Hands-on experience in cellular genomics, molecular biology, and technology development Experience with quantitative data analysis Experience with CRISPR targeting ES/iPS cells and/or single-cell technologies a plus Experience in multidisciplinary collaborations, management, and/or supervision Curiosity in research and creativity in problem-solving Strong interpersonal and collaboration skills; outstanding verbal and written communication abilities Ability to adapt to and effectively manage changes in a fast paced and dynamic environment A passion for science and sense of urgency to find new medicines to benefit patients
Education & Experience (required)
Bachelor's degree in related scientific field and four years of relevant work experience; or Master’s degree in a related scientific field and two years relevant experience; or PhD in related science field.
Knowledge, Skills And Abilities (required)
Comprehensive understanding of scientific principles Expert level knowledge and skills in field of science related to the research project General computer skills and experience with databases and scientific applications Strong analytical skills and excellent judgment Ability to work under deadlines with general guidance Excellent organizational skills and demonstrated ability to complete detailed work accurately Developing project management skills
Certifications & Licenses
None.
Physicial Requirements
Frequently stand, walk, twist, bend, stoop, squat, grasp lightly, use fine manipulation, grasp forcefully, perform desk-based computer tasks, use telephone, write by hand, lift, carry, push and pull objects Occasionally sit, kneel, crawl, reach and work above shoulders Rarely climb, scrub, sweep, mop, chop and operate hand and foot controls Must have correctible vision to perform duties Ability to move on hard surfaces for up to eight hours Ability to lift heavy objects weighing up to 50 pounds Position may require repetitive motion Reasonable accommodation available for applicants with disabilities
Working Conditions
May require working in close proximity to blood borne pathogens May require work in environments with animals used for teaching and research May work with hazardous materials and/or infectious diseases; PPE may be required May require extended or unusual work hours based on research requirements
Work Standards
Interpersonal Skills: ability to work well with Stanford colleagues, clients, and external organizations Promote Culture of Safety: commitment to safety and reporting concerns Comply with University policies and procedures
The expected pay range for this position is $93,062 to $111,670 per annum. The pay offered will be determined based on qualifications, responsibilities, budget, equity, location, and market pay.
Stanford is an equal employment opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law.
Applications: Submit via the Stanford web portal; email CV and cover letter to Prof. Jesse Engreitz (engreitz@stanford.edu).
#J-18808-Ljbffr