State University of New York at Buffalo
Research Scientist
State University of New York at Buffalo, New York, New York, United States
Are you excited by the prospect of joining a team-first research laboratory focused on identifying neural mechanisms underlying learning, memory, and decision-making in health as well as understanding their dysfunction in disease states? The laboratory of Prof. Dheeraj Roy in the Physiology and Biophysics Department at UB has an exciting Research Scientist opportunity to pursue these neuroscience directions. Our lab is also part of the Neuroscience program at UB.
Our group will address these fundamental biological questions using cutting-edge molecular and systems neuroscience techniques, including single-nuclei and spatial transcriptomics, the development of novel reporter tools using CRISPR/Cas9 that permit cell type-specific targeting in live animals, circuit tracing using whole-brain imaging techniques, physiological recordings from live animals using genetically-encoded calcium indicators (fiber photometry, single-cell-compatible miniscopes), manipulating individual cell types and their circuits during behavior using optogenetics, and human organoid models. We combine these experiments with significant computational approaches including machine learning, neural network modeling, and statistical analyses. While our research will start with basic science questions, the longer-term goal is to apply our knowledge to human disease models with the hope of identifying candidate therapeutic manipulations, either molecular target- or circuit-based, that can be translated to higher species.
Responsibilities
Setting up molecular and neuroscience techniques/protocols (35% effort)
Efficiently performing foundational experiments (35% effort)
Be responsible for mentoring and training future members (15% effort)
Contributing to grant and manuscript preparation (15% effort)
Enjoy working in a highly collaborative environment (within the laboratory, department, school, and across universities)
Benefits Working at UB comes with benefits that exceed salary alone. There are personal rewards including comprehensive health and retirement plan options. We also focus on creating and sustaining a healthy mix of work, personal and academic pursuit – all in an effort to support your work-life effectiveness. We support your growth and development through our career coaching and training department and we qualify as a public service loan forgiveness organization. Learn more about the great benefits the University at Buffalo has to offer.
Equal Opportunity As an Equal Opportunity / Affiantative Action employer, the Research Foundation will not discriminate in its employment practices due to an applicant’s race, color, religion, sex, sexual orientation, gender identity, national origin and veteran or disability status.
Minimum Qualifications
PhD in neuroscience, biology or related biomedical disciplines.
Preferred Qualifications
PhD with research experience in molecular biology, systems neuroscience, and/or computational approaches for analyzing RNA sequencing data, calcium imaging data, or AI-based behavioral clustering (e.g., deeplabcut). The candidate is expected to be proficient in maintaining mouse lines, performing intracortical surgeries followed by implantations for calcium imaging/optogenetics, and have good communication skills.
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Our group will address these fundamental biological questions using cutting-edge molecular and systems neuroscience techniques, including single-nuclei and spatial transcriptomics, the development of novel reporter tools using CRISPR/Cas9 that permit cell type-specific targeting in live animals, circuit tracing using whole-brain imaging techniques, physiological recordings from live animals using genetically-encoded calcium indicators (fiber photometry, single-cell-compatible miniscopes), manipulating individual cell types and their circuits during behavior using optogenetics, and human organoid models. We combine these experiments with significant computational approaches including machine learning, neural network modeling, and statistical analyses. While our research will start with basic science questions, the longer-term goal is to apply our knowledge to human disease models with the hope of identifying candidate therapeutic manipulations, either molecular target- or circuit-based, that can be translated to higher species.
Responsibilities
Setting up molecular and neuroscience techniques/protocols (35% effort)
Efficiently performing foundational experiments (35% effort)
Be responsible for mentoring and training future members (15% effort)
Contributing to grant and manuscript preparation (15% effort)
Enjoy working in a highly collaborative environment (within the laboratory, department, school, and across universities)
Benefits Working at UB comes with benefits that exceed salary alone. There are personal rewards including comprehensive health and retirement plan options. We also focus on creating and sustaining a healthy mix of work, personal and academic pursuit – all in an effort to support your work-life effectiveness. We support your growth and development through our career coaching and training department and we qualify as a public service loan forgiveness organization. Learn more about the great benefits the University at Buffalo has to offer.
Equal Opportunity As an Equal Opportunity / Affiantative Action employer, the Research Foundation will not discriminate in its employment practices due to an applicant’s race, color, religion, sex, sexual orientation, gender identity, national origin and veteran or disability status.
Minimum Qualifications
PhD in neuroscience, biology or related biomedical disciplines.
Preferred Qualifications
PhD with research experience in molecular biology, systems neuroscience, and/or computational approaches for analyzing RNA sequencing data, calcium imaging data, or AI-based behavioral clustering (e.g., deeplabcut). The candidate is expected to be proficient in maintaining mouse lines, performing intracortical surgeries followed by implantations for calcium imaging/optogenetics, and have good communication skills.
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