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Virginia Tech

Research Scientist

Virginia Tech, Washington, District of Columbia, us, 20022

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Job Description The Sahoo Lab is seeking a Research Scientist to help develop and lead our research program focused on the genetic and functional mechanisms driving bone marrow failure, clonal hematopoiesis, and progression to MDS/AML. The Research Scientist will have the opportunity to pursue an independent project while also contributing to collaborative efforts across the group, including mentoring and training junior scientists.

Available Projects Include

Germline predisposition to MDS/AML: Defining the mechanisms by which germline SAMD9L mutations cause hematopoietic failure and predispose to leukemogenesis.

Chromosome 7 aneuploidy syndromes: Modeling monosomy 7–associated bone marrow failure and understanding its contribution to clonal selection.

Clonal evolution and therapeutic vulnerabilities: Using single-cell sequencing platforms to track clonal evolution and identify novel therapeutic targets in high-risk MDS/AML.

Required Qualifications

Ph.D. in a biological science such as hematology, genetics, molecular biology, or cancer biology.

Demonstrated postdoctoral research experience with a strong publication record.

Strong expertise in experimental design and execution.

Proficiency in wet lab techniques, including molecular biology and mammalian cell culture.

Hands‑on experience working with primary cells such as iPSCs and hematopoietic stem cells.

Experience with CRISPR‑based genome editing and functional screens.

Self‑motivated, creative, and detail‑oriented researcher.

Excellent organizational and time‑management skills.

Ability to work independently and as part of a collaborative team.

Experience mentoring or training students and/or research staff.

Excellent communication skills.

Preferred Qualifications

Experience with mouse models of hematopoiesis or cancer.

Familiarity with single‑cell multi‑omics approaches.

Analysis of large scale genomic and/or transcriptomics data sets.

Employment Details

Age, color, disability, sex (including pregnancy), gender, gender identity, gender expression, genetic information, ethnicity or national origin, political affiliation, race, religion, sexual orientation, or military status: The university does not discriminate.

Supplemental drafting: The successful candidate will be required to have a criminal conviction check.

Salary Information: commensurate with experience.

Hours per week: 40+.

Overtime Status: Exempt; not eligible for overtime.

Review Date: 10/21/25.

About Virginia Tech Dedicated to its motto, Ut Prosim (That I May Serve), Virginia Tech pushes the boundaries of knowledge by taking a hands‑on, transdisciplinary approach to preparing scholars to be leaders and problem‑solvers. A comprehensive land‑grant institution that enhances the quality of life in Virginia and worldwide, Virginia Tech is an inclusive community dedicated to knowledge, discovery, and creativity. The university offers more than 280 majors to a diverse enrollment of more than 36,000 undergraduate, graduate, and professional students in eight undergraduate colleges, a school of medicine, a veterinary medicine college, Graduate School, and Honors College.

Virginia Tech endorses and encourages participation in professional development opportunities and university shared governance. These valuable contributions to university shared governance provide important representation and perspective, along with opportunities for unique and impactful professional development.

If you are an individual with a disability and desire an accommodation, please contact Brittany Shelton at sheltb@vtc.vt.edu during regular business hours at least 10 business days prior to the event.

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