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City of Hope, Inc.

Staff Scientist – Medicinal Chemistry

City of Hope, Inc., Duarte, California, United States, 91010

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Join the forefront of groundbreaking research at

City of Hope

where we are changing lives and making a real difference in the fight against cancer, diabetes, and other life‑threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission to contribute to innovative approaches in predicting, preventing, and curing diseases and shaping the future of medicine through cutting‑edge research.

Staff Scientist – Beckman Research Institute Base pay range: $38.00/hr – $127.00/hr

Responsibilities

Execute multi‑step synthesis of small molecules using modern automated purification systems and analytical equipment.

Collaborate with a dedicated team on the discovery and development of small molecule drugs and fragment‑based drug discovery.

Design and optimize synthetic pathways for small molecule candidates.

Contribute to project goals by employing efficient synthetic routes to produce target molecules.

Troubleshoot and resolve synthetic challenges to ensure high‑quality compound production.

Actively contribute to scientific discussions within the project team; report to the lab senior Staff Scientist and prepare and present research findings to project leaders and cross‑scientific and clinical discipline functional teams at City of Hope National Medical Center.

Maintain a safe and organized laboratory environment in strict adherence to Environmental Health and Safety (EHS) policies.

Ensure compliance with all record‑keeping, data integrity, and regulatory requirements, including any client‑specific standards.

Qualifications

Ph.D. in Medicinal Chemistry (awarded within the last 2 years).

Proven ability to independently perform small molecule synthesis in a standard chemistry lab environment.

Extensive hands‑on experience in organophosphorus and bisphosphonate chemistry within drug discovery research.

Expertise in common purification techniques for small organic molecules, such as chromatography (HPLC, LCMS), and characterization methods, including NMR and mass spectroscopy.

City of Hope employees receive pay based on work experience, qualifications, and work location.

City of Hope is an equal opportunity employer.

To learn more about our Comprehensive Benefits, please CLICK HERE.

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