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Hengrui Pharma

- (Boston)

Hengrui Pharma, Boston, Massachusetts, United States, 02298

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: Process Development & Optimization ////Lead downstream purification process development and optimization for biologics, including depth filtration, chromatography (affinity/ion exchange/hydrophobic interaction), ultrafiltration/diafiltration, virus inactivation/removal, etc. CQACPPAnalyze Critical Quality Attributes (CQA) and Critical Process Parameters (CPP) during purification, addressing challenges in yield, purity, host cell protein (HCP) residues, etc.

Technology Transfer & Regulatory Submissions AKTAGMPParticipate in pilot-scale purification process development (e.g., operation of AKTA systems), complete process scale-up and technology transfer to GMP manufacturing. SOPIND/BLADevelop technical documentation (process protocols, SOPs, validation protocols) and support IND/BLA submission dossier preparation.

Platform Development & Management Evaluate novel purification technologies (e.g., continuous flow chromatography, membrane chromatography) for potential implementation. Oversee daily instrument maintenance and other downstream process development-related tasks.

Masters degree or above in Bioengineering, Biochemistry, Pharmaceutical Engineering, or related disciplines.

Research projects involving protein purification experiments, with hands-on experience in operating relevant instruments.

Strong English proficiency (listening, speaking, reading, writing), capable of fluently interpreting English technical literature and conducting technical communication with international peers.

///Shanghai / Suzhou / Guangzhou / Lianyungang

1Western BlotAKTAProficient in fundamental experimental techniques (e.g.,

column packing ,

Western Blot );

Priority given to candidates with AKTA system operation experience . 2Understanding of downstream purification workflows (e.g., affinity chromatography, ion exchange). 3Excel/UNICORNBasic data analysis capabilities (Excel/UNICORN software).

Strong learning agility and deep interest in biopharmaceutical process development. Systematic thinking and data analysis skills, adaptable to fast-paced R&D environments. Independent problem-solving skills and cross-departmental collaboration mindset.