The Jackson Laboratory
Associate Research Scientist | Functional Genomics
The Jackson Laboratory, New York, New York, us, 10261
Associate Research Scientist | Functional Genomics page is loaded## Associate Research Scientist | Functional Genomicslocations:
New York, New Yorkposted on:
Posted 4 Days Agojob requisition id:
JR005545**Associate Research Scientist | Functional Genomics**JAX/NYSCF is seeking an Associate Research Scientist to join the Functional Genomics team as part of the NYSCF Global Stem Cell Array, a robotic system that automates both iPSC derivation, gene editing, and downstream differentiations.The Associate Research Scientist will **contribute to an innovative project centered on phenotyping cardiomyocytes derived from genetically diverse human induced pluripotent stem cell (hiPSC) lines**. This work aims to uncover the genetic basis of cardiotoxic responses and to advance predictive models of cardiovascular health through high-throughput functional screening, transcriptomics, and metabolomics.The project is highly collaborative, involving multidisciplinary teams across several institutions. The primary focus of the work you’ll do at JAX/NYSCF is developing automated protocols for the derivation/culture of iPSC-derived cardiomyocytes, drug testing, and sample preparation for downstream analyses, including imaging and single-cell sequencing.We want candidates with extensive **expertise in human pluripotent stem cell culture, directed differentiation into cardiomyocytes, and functional assays**. Experience with **cell culture automation (including liquid handling systems) or high-throughput assays is a major plus**.This role offers a unique opportunity to work with state-of-the-art screening technologies and automated platforms while contributing to impactful translational research in cardiac safety pharmacology and personalized medicine. As a Associate Research Scientist on the Functional Genomics team, you will:* Design, optimize, and execute experiments to advance a high-throughput iPSC-derived cardiomyocyte platform* Culture and expand iPSCs, generate iPSC-derived cardiomyocytes, and assess cardiomyocyte quality using automated liquid handling systems* Apply strong scientific knowledge and analytical skills to monitor, troubleshoot, and refine experimental workflows in real time.* Independently conduct literature reviews to identify and propose innovative experimental methods, procedures, or technologies* Contribute to project planning by preparing budgets, timelines, and resource estimates for supplies and equipment* Lead multiple, concurrent project components, ensuring progress toward research goals* Evaluate and document results, adapt methodologies as needed, and maintain compliance with regulatory standards* Communicate research goals and findings effectively, guiding team members and informing collaborators on past and future directions* Coordinate with external partners to explore new research opportunities
Foster a collaborative environment by sharing expertise and demonstrating openness to learning from others**Minimal requirements*** **PhD +3 years** of work experience in Cell Biology, Molecular Biology, Biomedical Engineering, or a related discipline.* Experience with **induced pluripotent stem cells** or **cardiomyocytes/ iPSC-derived cardiomyocytes**.* **Strong communication skills**, with the ability to clearly explain research findings and methodologies in both written and verbal formats, as well as effectively discuss, troubleshoot, and resolve experimental challenges with team members and collaborators.* Ability to **follow and adapt** protocols accurately.* Excellent **documentation and data managemen**t practices.**Preferred experience:*** Experience in differentiation of iPSC culture in cardiovascular lineages.* Exposure to automated cell culture systems (liquid handlers)* Electrophysiology experience is a plus* Flow cytometryPlease submit a Cover Letter and CV for application consideration.Pay Range: $65018 - $108857 per year, dependent upon experience.**About JAX:**The Jackson Laboratory is an independent, nonprofit biomedical research institution with a National Cancer Institute-designated Cancer Center and nearly 3,000 employees in locations across the United States (Maine, Connecticut, California), Japan and China. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health.Founded in 1929, JAX applies over nine decades of expertise in genetics to increase understanding of human disease, advancing treatments and cures for cancer, neurological and immune disorders, diabetes, aging and heart disease. It models and interprets genomic complexity, integrates basic research with clinical application, educates current and future scientists, and provides critical data, tools and services to the global biomedical community. For more information, please visit.**EEO Statement:***The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.*locations:
New York, New Yorkposted on:
Posted 4 Days Ago**Bar Harbor:**The Jackson Laboratory's 43-acre scenic Bar Harbor campus is nestled between the Gulf of Maine and the mountains of Acadia National Park. Some of the best hiking and biking in the world (over 50 square miles of mountains, lakes, views, and dramatic coastline) is accessible from our campus. We are one mile from downtown Bar Harbor, which offers a vibrant downtown district with a plethora of restaurants, shops, museums, and galleries.**Ellsworth:**The Charles E. Hewett Center in Ellsworth, Maine, is a state-of-the-art facility that serves researchers world wide. The facility represents the culmination of nine decades of unmatched experience and leadership in breeding and caring for laboratory mice.Ellsworth, Maine, is one of Maine’s fastest growing cities. With a growth rate of nearly 20%, Ellsworth is a bustling year-round community and acts as a hub for surrounding towns. It is located nearby Acadia National Park and hosts numerous special events, concerts and festivals each year. Residents have access to fabulous shopping, recreation, museums, galleries, and dining at a variety of independent restaurants.**Farmington:**JAX Genomic Medicine is transforming medicine by improving patient care, lowering costs, and increasing life span and health span. JAX Genomic Medicine’s research focuses on the complex genetic causes of disease and on the development of genomic solutions tailored to each person's unique genetic makeup.JAX Genomic Medicine sits on a 17-acre site on the campus of the University of Connecticut Health Center. The 183,500-square-foot facility opened in the fall of 2014. Now, it houses over 300 biomedical researchers, technicians, and support staff in state-of-the-art computing facilities and laboratories.In Connecticut, JAX resides in the scenic town of Farmington, in the state’s capitol region. The Hartford region, which offers some of the best public schools in the country, is made up of both bigger cities and smaller, charming historic New England towns.
JAX Genomic Medicine is also geographically located within 2 hours of Boston and New York and is close to multiple transportation systems, including bus lines, highways, railroads and international airports.**Sacramento:**The JAX Mice, Clinical and Research Services facility is located in Sacramento, the state capital of California.
Sacramento is less than a two-hour drive from San Francisco, Napa Valley, and scenic Lake Tahoe, and a short flight to both Los Angeles and Orange County.
Sacramento is #J-18808-Ljbffr
New York, New Yorkposted on:
Posted 4 Days Agojob requisition id:
JR005545**Associate Research Scientist | Functional Genomics**JAX/NYSCF is seeking an Associate Research Scientist to join the Functional Genomics team as part of the NYSCF Global Stem Cell Array, a robotic system that automates both iPSC derivation, gene editing, and downstream differentiations.The Associate Research Scientist will **contribute to an innovative project centered on phenotyping cardiomyocytes derived from genetically diverse human induced pluripotent stem cell (hiPSC) lines**. This work aims to uncover the genetic basis of cardiotoxic responses and to advance predictive models of cardiovascular health through high-throughput functional screening, transcriptomics, and metabolomics.The project is highly collaborative, involving multidisciplinary teams across several institutions. The primary focus of the work you’ll do at JAX/NYSCF is developing automated protocols for the derivation/culture of iPSC-derived cardiomyocytes, drug testing, and sample preparation for downstream analyses, including imaging and single-cell sequencing.We want candidates with extensive **expertise in human pluripotent stem cell culture, directed differentiation into cardiomyocytes, and functional assays**. Experience with **cell culture automation (including liquid handling systems) or high-throughput assays is a major plus**.This role offers a unique opportunity to work with state-of-the-art screening technologies and automated platforms while contributing to impactful translational research in cardiac safety pharmacology and personalized medicine. As a Associate Research Scientist on the Functional Genomics team, you will:* Design, optimize, and execute experiments to advance a high-throughput iPSC-derived cardiomyocyte platform* Culture and expand iPSCs, generate iPSC-derived cardiomyocytes, and assess cardiomyocyte quality using automated liquid handling systems* Apply strong scientific knowledge and analytical skills to monitor, troubleshoot, and refine experimental workflows in real time.* Independently conduct literature reviews to identify and propose innovative experimental methods, procedures, or technologies* Contribute to project planning by preparing budgets, timelines, and resource estimates for supplies and equipment* Lead multiple, concurrent project components, ensuring progress toward research goals* Evaluate and document results, adapt methodologies as needed, and maintain compliance with regulatory standards* Communicate research goals and findings effectively, guiding team members and informing collaborators on past and future directions* Coordinate with external partners to explore new research opportunities
Foster a collaborative environment by sharing expertise and demonstrating openness to learning from others**Minimal requirements*** **PhD +3 years** of work experience in Cell Biology, Molecular Biology, Biomedical Engineering, or a related discipline.* Experience with **induced pluripotent stem cells** or **cardiomyocytes/ iPSC-derived cardiomyocytes**.* **Strong communication skills**, with the ability to clearly explain research findings and methodologies in both written and verbal formats, as well as effectively discuss, troubleshoot, and resolve experimental challenges with team members and collaborators.* Ability to **follow and adapt** protocols accurately.* Excellent **documentation and data managemen**t practices.**Preferred experience:*** Experience in differentiation of iPSC culture in cardiovascular lineages.* Exposure to automated cell culture systems (liquid handlers)* Electrophysiology experience is a plus* Flow cytometryPlease submit a Cover Letter and CV for application consideration.Pay Range: $65018 - $108857 per year, dependent upon experience.**About JAX:**The Jackson Laboratory is an independent, nonprofit biomedical research institution with a National Cancer Institute-designated Cancer Center and nearly 3,000 employees in locations across the United States (Maine, Connecticut, California), Japan and China. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health.Founded in 1929, JAX applies over nine decades of expertise in genetics to increase understanding of human disease, advancing treatments and cures for cancer, neurological and immune disorders, diabetes, aging and heart disease. It models and interprets genomic complexity, integrates basic research with clinical application, educates current and future scientists, and provides critical data, tools and services to the global biomedical community. For more information, please visit.**EEO Statement:***The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.*locations:
New York, New Yorkposted on:
Posted 4 Days Ago**Bar Harbor:**The Jackson Laboratory's 43-acre scenic Bar Harbor campus is nestled between the Gulf of Maine and the mountains of Acadia National Park. Some of the best hiking and biking in the world (over 50 square miles of mountains, lakes, views, and dramatic coastline) is accessible from our campus. We are one mile from downtown Bar Harbor, which offers a vibrant downtown district with a plethora of restaurants, shops, museums, and galleries.**Ellsworth:**The Charles E. Hewett Center in Ellsworth, Maine, is a state-of-the-art facility that serves researchers world wide. The facility represents the culmination of nine decades of unmatched experience and leadership in breeding and caring for laboratory mice.Ellsworth, Maine, is one of Maine’s fastest growing cities. With a growth rate of nearly 20%, Ellsworth is a bustling year-round community and acts as a hub for surrounding towns. It is located nearby Acadia National Park and hosts numerous special events, concerts and festivals each year. Residents have access to fabulous shopping, recreation, museums, galleries, and dining at a variety of independent restaurants.**Farmington:**JAX Genomic Medicine is transforming medicine by improving patient care, lowering costs, and increasing life span and health span. JAX Genomic Medicine’s research focuses on the complex genetic causes of disease and on the development of genomic solutions tailored to each person's unique genetic makeup.JAX Genomic Medicine sits on a 17-acre site on the campus of the University of Connecticut Health Center. The 183,500-square-foot facility opened in the fall of 2014. Now, it houses over 300 biomedical researchers, technicians, and support staff in state-of-the-art computing facilities and laboratories.In Connecticut, JAX resides in the scenic town of Farmington, in the state’s capitol region. The Hartford region, which offers some of the best public schools in the country, is made up of both bigger cities and smaller, charming historic New England towns.
JAX Genomic Medicine is also geographically located within 2 hours of Boston and New York and is close to multiple transportation systems, including bus lines, highways, railroads and international airports.**Sacramento:**The JAX Mice, Clinical and Research Services facility is located in Sacramento, the state capital of California.
Sacramento is less than a two-hour drive from San Francisco, Napa Valley, and scenic Lake Tahoe, and a short flight to both Los Angeles and Orange County.
Sacramento is #J-18808-Ljbffr