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Genezen

QC Technical Services Analyst II/III

Genezen, Lexington, Massachusetts, United States, 02173

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The field of gene therapy is growing rapidly and Genezen is here to meet the exacting needs of our clients. We provide process development, produce GMP viral vectors, and provide cell transduction for gene and cell therapy clinical trials and are proud to be a part of the process that leads to new cures. WORKING AT GENEZEN Manypeople have worked in environments where you feel like just another nameless part of an enormous machine. Genezen is different. We want our employees to be innovative, collaborative problem solvers who are dedicated to meeting the challenges of working at a fast-growing company. We are dedicated to empowering our employees to be their best and making Genezen a rewarding place to work. Every employee contributes to the success of the company and you can be part of that team. JOB SUMMARY The individual in this role will work collaboratively with the analytical development, quality control, and quality assurance teams to support successful transfer and implementation of QC analytical methods for the testing of viral vectors and gene therapy products in support of Genezen’s services and commercial products. The role includes executing assays, training personnel, managing materials, and generating documentation in compliance with cGMP standards and regulatory guidelines. Additionally, the role contributes to critical material and method lifecycle management and documentation. ESSENTIAL JOB FUNCTIONS Support the implementation and technology transfer of QC analytical methods, including assay execution, personnel training, procurement of materials and reagents, documentation generation, and facilitation of knowledge transfer. Execute Performance Qualification (PQ) activities for new equipment. Compile and analyze data to support tech transfer and method implementation. Draft and revise equipment operational SOPs and method SOPs/worksheets in accordance with cGMP. Receive training on new analytical methods and support assay execution during tech transfer. Conduct QC Operations training for new methods and equipment. Manage Bill of Materials (BOM) creation and coordinate procurement for tech transfer activities. Critical Material Management Lead inventory maintenance of critical materials, including freezer mapping and QC handoffs. Support lifecycle management of critical materials, including qualification/re-qualification and COA review and generation. Assist with data trending and compilation of trend reports. Method Life Cycle and Documentation Support drafting of protocols and reports for QC method transfer, qualification, verification, and validation. Review, revise, and maintain procedures, including protocols and technical reports. Assist in lifecycle maintenance of laboratory procedures and SOP updates. Support QMS related activities by generating documentation to support change controls/deviations/investigations in eDMS systems. Assist in assay troubleshooting and support continuous improvement initiatives. SPECIAL JOB REQUIREMENTS Adaptability required as work schedule may change based on business needs Criminal background check required Other duties as assigned KNOWLEDGE, SKILLS AND EXPERIENCE EDUCATION / CERTIFICATIONS / LICENSES BS or higher degree in Biology, Biochemistry, Molecular Biology or related Life Sciences ON-THE-JOB EXPERIENCE 5+ years of relevant industry experience in QC 2+ years of relevant experience with gene Therapy/Viral vector production Desired SKILLS / ABILITIES Experience with laboratory techniques (qPCR, ddPCR, ELISA, cell based assays etc.) Computer/software literacy (MS Word, Excel, JMP, Minitab, and LIMS etc.) Ability to thrive in a quickly changing, CDMO environment where flexibility and teamwork is essential Ability to work in a fast-paced, collaborative environment, and able to manage workload based on changing priorities Experience with technical writing skills such as protocol, reports, procedures etc. Good/effective communication and organizational skills with the ability to work well with others and independently Ability to work collaboratively with cross functional departments PHYSICAL DEMANDS While performing the duties of this job, the employee is required to meet the following physical demands: Regularly sit for long periods of time Movement Frequently required to stand; sit; walk; balance; stoop; kneel; crouch; use hands to finger, handle, or feel; reach with hands and arms Occasionally required to walk; climb or balance; and stoop, kneel, crouch, or crawl Lifting Frequently lift and/or move up to 10 pounds Rarely lift and/or move up to 25 pounds Vision Frequently required to communicate by talking, hearing, using telephone and e-mail GENEZEN'S CURES VALUE-BASED COMPETENCIES C ommitted to Science We are committed toscientific excellence, staying current with industry developments, making data-driven decisions, and pursuing innovation to advance healthcare. U rgency in action for the patients We operate with urgency and a commitment to delivering timely treatments to patients by accelerating our partners' programs. R esilience & Grit in operations We are committed to overcoming challenges, learning from failures, and persistently striving for success. E xecute with Excellence & Integrity We are dedicated to delivering quality results and upholding ethical principals. S olutions driven for our partners We are committed to being a proactive, collaborative, creative and open-minded partner. GENEZEN'S BENEFITS Paid vacation days, amount based on tenure 401(k) plan with company match up to 6% of salary, vested immediately Choice of several healthcare plans FSA and HSA programs Employer-paid basic term life/personal accident insurance Voluntary disability, universal life/personal accident insurance ADDITIONAL DETAILS Nothing in the job description for this role restricts management’s right to assign or reassign duties and responsibilities to this job at any time. This position requires a criminal background check. Genezen is an Equal Opportunity Employer. Genezen participates in EVerify. Genezen is interested in every qualified candidate who is eligible to work in the United States; however, we are not able to sponsor visas. Genezen has operates two locations: one in Fishers, Indiana and the second in Lexington, Massachusetts. Fishers is a suburb of Indianapolis. Fishers was named the #1 place to live in the US by Money Magazine in 2017 for its livability, safety and entrepreneurship. Fishers is one of the fastest growing communities in Indiana and is dedicated to supporting a high quality of life for all its residents. Nearby Indianapolis is home to professional and college sports teams, the Indy 500, a growing art community and the world’s largest children’s museum--to name just a few reasons why this area is a great place to live. Lexington, Massachusetts, located just northwest of Boston, is renowned as a historic suburb with a rich cultural heritage. It boasts picturesque New England charm, tree-lined streets, and a vibrant community. Known for its pivotal role in the American Revolution, Lexington offers visitors and residents alike a blend of historical landmarks, modern amenities, and a strong sense of community pride. Create a Job Alert Interested in building your career at Genezen? 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We are a federal contractor or subcontractor. The law requires us to provide equal employment opportunity to qualified people with disabilities. We have a goal of having at least 7% of our workers as people with disabilities. The law says we must measure our progress towards this goal. To do this, we must ask applicants and employees if they have a disability or have ever had one. People can become disabled, so we need to ask this question at least every five years. Completing this form is voluntary, and we hope that you will choose to do so. Your answer is confidential. No one who makes hiring decisions will see it. Your decision to complete the form and your answer will not harm you in any way. If you want to learn more about the law or this form, visit the U.S. Department of Labor’s Office of Federal Contract Compliance Programs (OFCCP) website at www.dol.gov/ofccp . How do you know if you have a disability? A disability is a condition that substantially limits one or more of your “major life activities.” If you have or have ever had such a condition, you are a person with a disability.

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