MSD
Post Doctoral Research Fellow - Infectious Disease & Vaccines: Immunology
MSD, West Point, Nebraska, United States, 68788
Overview
We are a global health care leader with a diversified portfolio of prescription medicines, vaccines, and consumer health products, as well as animal health products. Today, we are building a new kind of healthcare company – one that is ready to help create a healthier future for all of us. Our ability to excel depends on the integrity, knowledge, imagination, skill, diversity, and teamwork of people like you. To this end, we strive to create an environment of mutual respect, encouragement, and teamwork. As part of our global team, you’ll have the opportunity to collaborate with talented and dedicated colleagues while developing and expanding your career. Be a part of the legacy: Our Postdoctoral Research Fellow Program aims to be a best-in-industry program for industrial postdoctoral researchers, designed to provide you with an academic focus in a commercial environment. With the resources, reach, and expertise of a large pharmaceutical company, postdoctoral researchers will be positioned to excel in an institution committed to breakthrough innovation in research and discovery.
Position Overview
We are seeking a talented and motivated candidate with expertise in immunology or vaccinology and a strong interest in adaptive immunological memory to join the Infectious Disease & Vaccines: Immunology group at our company’s West Point, PA site. As a postdoctoral fellow in Infectious Disease & Vaccines, you will work with a highly collaborative team of scientists across functional and therapeutic areas to investigate basic immunological mechanisms regulating vaccine durability. The successful candidate will be responsible for launching independent projects that interrogate how decisions made during vaccine design impact the development of immunological memory, with a primary focus on the development of long-lived plasma cells and memory B cells. The postdoctoral fellow will collaborate closely with a mentor to develop research plans, enable model development, conduct mechanistic studies, and generate novel insights which can be leveraged to generate more durable vaccine responses.
Responsibilities
Establishment and optimization of vaccine models in pre-clinical animal species. Development of immunological assays to characterize antigen-specific humoral and cellular immune responses. Performing single cell assays including high-parameter flow cytometry and single cell omics profiling (e.g. single cell RNAseq, BCRseq, and ATACseq). Data interpretation, manuscript and patent preparation, publication, and presentation.
Education Minimum Requirement
Ph.D. within 6 months of hire in Immunology, Vaccinology, or related field.
Required Experience and Skills
Expertise in the in vivo development of adaptive immunological memory. Hands-on experience working with pre-clinical animal models and manipulating samples derived from these models. Hands-on experience and solid knowledge in aseptic techniques in tissue culture. Hands-on experience and solid knowledge in molecular biology. Hands-on experience with in vitro assay development and troubleshooting. Experience in immunological assays (e.g. ELISA, ELISPOT, high-parameter flow cytometry, cell sorting, in vitro restimulation assays). Strong publication record and ability to design and execute experiments and interpret data. Excellent communication and collaboration skills.
Preferred Skills
Expertise in B cell differentiation and B cell responses to vaccination or infection. Familiarity with BSL2 level viral pathogens (e.g. SARS-CoV2, RSV, etc.). Familiarity or experience with single-cell omics assays and data analysis. Familiarity or experience with BCR repertoire sequencing and analysis. Familiarity or experience with novel vaccine adjuvants and/or vaccine platforms.
Note: The following items may be present in the original description as placeholders or unrelated sections but are not required for the core job information:
Current Employees apply in plain text, Current Contingent Workers apply in plain text.
Required Skills
Accountability, Accountability, Adaptability, Analytical Chemistry, Assay Development, Cell-Based Assays, Cell Culture Techniques, Clinical Immunology, Computational Biology, Data Analysis, Flow Cytometry, Global Health, Immunoassays, Immunology, Immunotherapy, Infectious Disease, In Vitro Assays, In Vivo Mouse Models, Leadership, Mathematical Biology, Molecular Biology, Programming Languages, Research Planning, Scientific Writing, siRNA Knockdown
Preferred Skills
Current Employees apply (text only); Current Contingent Workers apply (text only).
US and Puerto Rico Residents Only
Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please indicate if you need an accommodation during the application or hiring process.
As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other legally protected characteristics. As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit: EEOC Know Your Rights EEOC GINA Supplement
We are proud to be a company that embraces the value of bringing together talented and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively. Learn more about your rights, including under California, Colorado and other US State Acts
U.S. Hybrid Work Model
Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, Monday - Thursday, with Friday designated as remote-working, unless business critical tasks require an on-site presence. This model does not apply to field-based, facility-based, manufacturing-based, or research-based positions located at a Company site; or roles designated as remote. Hybrid guidance does not apply to roles with no remote option.
San Francisco Residents Only:
We will consider qualified applicants with arrest and conviction records in compliance with the San Francisco Fair Chance Ordinance.
Los Angeles Residents Only:
We will consider all qualified applicants, including those with criminal histories, in a manner consistent with applicable state and local laws.
Search Firm Representatives: The company does not accept unsolicited assistance from search firms for employment opportunities. All CVs/resumes submitted by search firms without a valid written agreement will be the property of the company.
Employee Status:
Regular Relocation:
Domestic VISA Sponsorship:
Yes Travel Requirements:
10% Flexible Work Arrangements:
Not Applicable Shift:
Not Indicated Valid Driving License:
No Hazardous Materials:
N/A Job Posting End Date:
10/31/2025 *A job posting is effective until 11:59:59PM on the day before the listed job posting end date. Please ensure you apply to a job posting no later than the day before the job posting end date.
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We are a global health care leader with a diversified portfolio of prescription medicines, vaccines, and consumer health products, as well as animal health products. Today, we are building a new kind of healthcare company – one that is ready to help create a healthier future for all of us. Our ability to excel depends on the integrity, knowledge, imagination, skill, diversity, and teamwork of people like you. To this end, we strive to create an environment of mutual respect, encouragement, and teamwork. As part of our global team, you’ll have the opportunity to collaborate with talented and dedicated colleagues while developing and expanding your career. Be a part of the legacy: Our Postdoctoral Research Fellow Program aims to be a best-in-industry program for industrial postdoctoral researchers, designed to provide you with an academic focus in a commercial environment. With the resources, reach, and expertise of a large pharmaceutical company, postdoctoral researchers will be positioned to excel in an institution committed to breakthrough innovation in research and discovery.
Position Overview
We are seeking a talented and motivated candidate with expertise in immunology or vaccinology and a strong interest in adaptive immunological memory to join the Infectious Disease & Vaccines: Immunology group at our company’s West Point, PA site. As a postdoctoral fellow in Infectious Disease & Vaccines, you will work with a highly collaborative team of scientists across functional and therapeutic areas to investigate basic immunological mechanisms regulating vaccine durability. The successful candidate will be responsible for launching independent projects that interrogate how decisions made during vaccine design impact the development of immunological memory, with a primary focus on the development of long-lived plasma cells and memory B cells. The postdoctoral fellow will collaborate closely with a mentor to develop research plans, enable model development, conduct mechanistic studies, and generate novel insights which can be leveraged to generate more durable vaccine responses.
Responsibilities
Establishment and optimization of vaccine models in pre-clinical animal species. Development of immunological assays to characterize antigen-specific humoral and cellular immune responses. Performing single cell assays including high-parameter flow cytometry and single cell omics profiling (e.g. single cell RNAseq, BCRseq, and ATACseq). Data interpretation, manuscript and patent preparation, publication, and presentation.
Education Minimum Requirement
Ph.D. within 6 months of hire in Immunology, Vaccinology, or related field.
Required Experience and Skills
Expertise in the in vivo development of adaptive immunological memory. Hands-on experience working with pre-clinical animal models and manipulating samples derived from these models. Hands-on experience and solid knowledge in aseptic techniques in tissue culture. Hands-on experience and solid knowledge in molecular biology. Hands-on experience with in vitro assay development and troubleshooting. Experience in immunological assays (e.g. ELISA, ELISPOT, high-parameter flow cytometry, cell sorting, in vitro restimulation assays). Strong publication record and ability to design and execute experiments and interpret data. Excellent communication and collaboration skills.
Preferred Skills
Expertise in B cell differentiation and B cell responses to vaccination or infection. Familiarity with BSL2 level viral pathogens (e.g. SARS-CoV2, RSV, etc.). Familiarity or experience with single-cell omics assays and data analysis. Familiarity or experience with BCR repertoire sequencing and analysis. Familiarity or experience with novel vaccine adjuvants and/or vaccine platforms.
Note: The following items may be present in the original description as placeholders or unrelated sections but are not required for the core job information:
Current Employees apply in plain text, Current Contingent Workers apply in plain text.
Required Skills
Accountability, Accountability, Adaptability, Analytical Chemistry, Assay Development, Cell-Based Assays, Cell Culture Techniques, Clinical Immunology, Computational Biology, Data Analysis, Flow Cytometry, Global Health, Immunoassays, Immunology, Immunotherapy, Infectious Disease, In Vitro Assays, In Vivo Mouse Models, Leadership, Mathematical Biology, Molecular Biology, Programming Languages, Research Planning, Scientific Writing, siRNA Knockdown
Preferred Skills
Current Employees apply (text only); Current Contingent Workers apply (text only).
US and Puerto Rico Residents Only
Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please indicate if you need an accommodation during the application or hiring process.
As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other legally protected characteristics. As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit: EEOC Know Your Rights EEOC GINA Supplement
We are proud to be a company that embraces the value of bringing together talented and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively. Learn more about your rights, including under California, Colorado and other US State Acts
U.S. Hybrid Work Model
Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, Monday - Thursday, with Friday designated as remote-working, unless business critical tasks require an on-site presence. This model does not apply to field-based, facility-based, manufacturing-based, or research-based positions located at a Company site; or roles designated as remote. Hybrid guidance does not apply to roles with no remote option.
San Francisco Residents Only:
We will consider qualified applicants with arrest and conviction records in compliance with the San Francisco Fair Chance Ordinance.
Los Angeles Residents Only:
We will consider all qualified applicants, including those with criminal histories, in a manner consistent with applicable state and local laws.
Search Firm Representatives: The company does not accept unsolicited assistance from search firms for employment opportunities. All CVs/resumes submitted by search firms without a valid written agreement will be the property of the company.
Employee Status:
Regular Relocation:
Domestic VISA Sponsorship:
Yes Travel Requirements:
10% Flexible Work Arrangements:
Not Applicable Shift:
Not Indicated Valid Driving License:
No Hazardous Materials:
N/A Job Posting End Date:
10/31/2025 *A job posting is effective until 11:59:59PM on the day before the listed job posting end date. Please ensure you apply to a job posting no later than the day before the job posting end date.
#J-18808-Ljbffr