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System One

Manufacturing Associate (Upstream & Downstream)

System One, Trenton, New Jersey, United States

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Manufacturing Associate (Upstream & Downstream) Location:

Princeton Area, New Jersey Employment Type:

Temp-to-Hire (potential direct opportunity for the right fit) Schedule:

Full-time, shift flexibility required (day, evening, overnight rotation possible) Pay Range:

$20–$25/hour (based on experience) Overtime:

Available based on production needs

Position Summary Support both Upstream and Downstream manufacturing operations in a cGMP-compliant environment. This role provides hands-on experience throughout the biologics production process — from cell culture to protein purification.

Ideal Candidate Profile 1–5 years of GMP experience in Pharmaceuticals, Biologics, Medical Devices, Cleanroom, or Chemical Processing environments Comfortable working in sterile/cleanroom settings and following strict protocols Strong interest in cross-functional manufacturing roles with growth potential Open to flexible hours outside of a standard 8am–5pm schedule Open to Temp-to-Hire employment Key Responsibilities

Upstream Manufacturing

Prepare media and buffers Thaw vials, expand seed trains, and operate bioreactors (fed-batch/perfusion) Monitor/document cell growth and bioreactor parameters Support cell harvest through clarification and filtration Downstream Manufacturing

Conduct chromatography operations (AKTA or similar systems) Perform Tangential Flow Filtration (TFF) and diafiltration Execute viral filtration procedures Support cleanroom-based final fill operations General Duties

Adhere to cleanroom, gowning, and aseptic protocols Maintain GMP-compliant documentation Clean and sanitize production equipment Collaborate with Quality, Engineering, and Logistics teams Education Requirements

High School Diploma or Associate’s Degree with 1–5 years of relevant GMP experience OR Bachelor’s Degree in Biotechnology, Biochemistry, Microbiology, Chemical Engineering, or related field Desired Experience Upstream

Familiarity with aseptic techniques and bioreactor operation Experience with cell culture, buffer/media prep Downstream

Understanding of chromatography, TFF, viral filtration Hands-on experience in cleanroom/purification operations General

Ability to stand for long periods and lift up to 50 lbs Strong attention to detail and documentation skills Willingness to cross-train and support evolving production needs Interview Process

Typically one onsite interview Meet with hiring managers/supervisors Expect situational and GMP-related questions

#M3- #LI- #DI-

Ref: #558-Scientific #J-18808-Ljbffr