Mayo Clinic
Research Technologist - Zadeh Lab Neurologic Surgery
Mayo Clinic, Rochester, Minnesota, us, 55905
Why Mayo Clinic
Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans – to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.
Benefits Highlights
Medical: Multiple plan options.
Dental: Delta Dental or reimbursement account for flexible coverage.
Vision: Affordable plan with national network.
Pre-Tax Savings: HSA and FSAs for eligible expenses.
Retirement: Competitive retirement package to secure your future.
Responsibilities We are seeking a highly motivated and detail-oriented Research Technologist to join our translational neuro-oncology research team. Our lab focuses on glioblastoma, meningiomas, and peripheral nerve sheath tumors, with a strong emphasis on tumor microenvironment biology, spatial and single-cell transcriptomics, and molecular biomarker discovery through epigenetic modifications.
Methylated DNA immunoprecipitation from FFPE and frozen tumor tissues, CSF and plasma
Molecular biology assays (PCR, RNA/DNA extraction, qPCR, bisulfite conversion)
H&E staining, immunohistochemistry and immunofluorescence staining on FFPE and frozen tissues
Fluorescence and brightfield microscopy, image acquisition, and analysis
Sample preparation for spatial transcriptomics, single-cell analysis, and next-generation sequencing
Data entry, preliminary statistical analysis, and assistance with manuscript and figure preparation
Organization of lab inventory, reagents, and general lab maintenance
The Research Technologist will present data in lab meetings and collaborate closely with senior lab members and trainees. The candidate will be expected to work independently on routine procedures and receive mentorship for more complex tasks. Opportunities for authorship on publications are available based on contributions.
Qualifications
Requires bachelor's degree in biology, chemistry, other relevant science, or an associates degree with 6 years of relevant laboratory experience. Bachelor’s degree in biology, biomedical sciences, or a related field is preferred. (Master’s degree or relevant research experience preferred)
Strong preference will be given to those who have a minimum of 3 year of hands-on wet lab experience (academic or industry); associate degree with extensive relevant lab experience will also be considered
Proficiency in molecular biology techniques PCR and qPCR preferred
Familiarity with immunostaining, microscopy, and basic data analysis (GraphPad, ImageJ, Excel/R) preferred
Excellent organizational skills, attention to detail, and ability to work both independently and collaboratively
Strong communication and documentation skills
Experience with DNA methylation, digital pathology, or prior exposure to spatial transcriptomics is an asset but not required. Training will be provided.
Compensation Education, experience and tenure may be considered along with internal equity when job offers are extended.; $27.44-41.16/ hour
Equal Opportunity All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the "EOE is the Law" . Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.
Recruiter Jill Squier
#J-18808-Ljbffr
Benefits Highlights
Medical: Multiple plan options.
Dental: Delta Dental or reimbursement account for flexible coverage.
Vision: Affordable plan with national network.
Pre-Tax Savings: HSA and FSAs for eligible expenses.
Retirement: Competitive retirement package to secure your future.
Responsibilities We are seeking a highly motivated and detail-oriented Research Technologist to join our translational neuro-oncology research team. Our lab focuses on glioblastoma, meningiomas, and peripheral nerve sheath tumors, with a strong emphasis on tumor microenvironment biology, spatial and single-cell transcriptomics, and molecular biomarker discovery through epigenetic modifications.
Methylated DNA immunoprecipitation from FFPE and frozen tumor tissues, CSF and plasma
Molecular biology assays (PCR, RNA/DNA extraction, qPCR, bisulfite conversion)
H&E staining, immunohistochemistry and immunofluorescence staining on FFPE and frozen tissues
Fluorescence and brightfield microscopy, image acquisition, and analysis
Sample preparation for spatial transcriptomics, single-cell analysis, and next-generation sequencing
Data entry, preliminary statistical analysis, and assistance with manuscript and figure preparation
Organization of lab inventory, reagents, and general lab maintenance
The Research Technologist will present data in lab meetings and collaborate closely with senior lab members and trainees. The candidate will be expected to work independently on routine procedures and receive mentorship for more complex tasks. Opportunities for authorship on publications are available based on contributions.
Qualifications
Requires bachelor's degree in biology, chemistry, other relevant science, or an associates degree with 6 years of relevant laboratory experience. Bachelor’s degree in biology, biomedical sciences, or a related field is preferred. (Master’s degree or relevant research experience preferred)
Strong preference will be given to those who have a minimum of 3 year of hands-on wet lab experience (academic or industry); associate degree with extensive relevant lab experience will also be considered
Proficiency in molecular biology techniques PCR and qPCR preferred
Familiarity with immunostaining, microscopy, and basic data analysis (GraphPad, ImageJ, Excel/R) preferred
Excellent organizational skills, attention to detail, and ability to work both independently and collaboratively
Strong communication and documentation skills
Experience with DNA methylation, digital pathology, or prior exposure to spatial transcriptomics is an asset but not required. Training will be provided.
Compensation Education, experience and tenure may be considered along with internal equity when job offers are extended.; $27.44-41.16/ hour
Equal Opportunity All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the "EOE is the Law" . Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.
Recruiter Jill Squier
#J-18808-Ljbffr