Inotiv
Job Summary
Lead research technician assists the Gastrointestinal team personnel in coordinating efforts on the day-to-day operations of active studies. They assist Study Directors and Study Coordinators in accurately and efficiently conducting animal studies and supervise the in-life study execution, clinical observations, and treatments to ensure compliance with policies and procedures. They also provide leadership, training, and technical oversight to more junior technicians.
Primary Responsibilities
Directly work with the Gastrointestinal group to conduct required study activities.
Assist in disease induction procedures.
Assist with the preparation and execution of necropsies, tissue collection (terminal and interim) and surgeries for the Gastrointestinal department.
Review facility schedules, dose formulation calculations, cage cards, spreadsheets, and study protocols for consistency and accuracy before the first dose event.
Independently perform tissue collections and dosing after training with PI.
Read and understand IACUC protocols, SOPs, and all study protocols, demonstrating familiarity with critical timepoints.
Perform critical data collections for the Gastrointestinal team, including weighing, clinical observations, health assessments, post operative monitoring, and disease progression scoring.
Administer doses of compounds to rats and mice via common dosing routes, including but not limited to oral, intravenous, subcutaneous, and intraperitoneal injection.
Perform blood collections from rats and mice via tail vein, retro-orbital, and terminal blood draws and process these samples via centrifugation for plasma and/or serum.
Review live phase data on all active studies for consistency and accuracy.
Assist in formulating experimental compounds for administration.
Use general laboratory equipment, including balances, syringes and needles, blood collection tubes, centrifuges, pipettes, formalin jars, liquid nitrogen, ‑80 freezers, incubators, fluid/syringe pumps, chemical and clean hoods, PPE (lab coat, gloves, face mask or respirator, shoe covers, hair nets, eye protection), quarantine/isolation rooms, autoclaves, necropsy hand tools.
Additional tasks as assigned.
Secondary Responsibilities
Assist PIs and Study Coordinators to ensure study protocol, schedules, formulations, and sample collections are correct and properly communicated to the research team.
Assist Study Coordinators with the creation or verification of cage cards, sample collection prep labels, and data files.
Maintain study‑related forms (e.g. data sheets, health assessments, found dead form, moribund form).
Keep laboratory clean and maintain inventory of all team supplies (media, plates, reagents, surgical tools, etc.) and study‑specific test articles.
Support and participate in other duties and company initiatives as directed.
Utilize various software applications sustained by a Windows platform (Excel, Word, PowerPoint, etc.).
Education & Experience
M.S./B.S./B.A. in science (biology or equivalent; immunology preferred) with 1-3 years of direct animal behavioral work experience, or associate degree with 4 years direct laboratory animal work experience, or 6 years of direct laboratory animal work experience without a college science degree, or equivalent combination of related education and required work experience will be considered with management approval.
AAALAS Certification or commitment to attaining certification.
Preferred animal laboratory research experience with mice and rats, including dosing, in‑life sample collections, and necropsy collections.
Skills & Abilities
Demonstrates a working knowledge and awareness of general laboratory procedures.
Demonstrates an ability to follow detailed instructions, work independently, and in a team environment.
Demonstrates an ability to use a computer software to compile and maintain study data and reports for study records and sample inventory.
Demonstrates a positive attitude and respect for co‑workers, managers, and other employees.
Exhibits a basic understanding of GLP, AAALAC, OLAW, USDA, OHS, PHS, The Guide, and IACUC regulations and standards with consistent application of these practices.
Exhibits accuracy performing laboratory operations.
Exhibits an aptitude for quality, an eye for detail, the ability to follow written instructions and work with a minimum of supervision.
Exhibits good written and oral communication skills and suitable organization skills.
Maintains a commitment to adhere to all safety regulations and procedures.
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Primary Responsibilities
Directly work with the Gastrointestinal group to conduct required study activities.
Assist in disease induction procedures.
Assist with the preparation and execution of necropsies, tissue collection (terminal and interim) and surgeries for the Gastrointestinal department.
Review facility schedules, dose formulation calculations, cage cards, spreadsheets, and study protocols for consistency and accuracy before the first dose event.
Independently perform tissue collections and dosing after training with PI.
Read and understand IACUC protocols, SOPs, and all study protocols, demonstrating familiarity with critical timepoints.
Perform critical data collections for the Gastrointestinal team, including weighing, clinical observations, health assessments, post operative monitoring, and disease progression scoring.
Administer doses of compounds to rats and mice via common dosing routes, including but not limited to oral, intravenous, subcutaneous, and intraperitoneal injection.
Perform blood collections from rats and mice via tail vein, retro-orbital, and terminal blood draws and process these samples via centrifugation for plasma and/or serum.
Review live phase data on all active studies for consistency and accuracy.
Assist in formulating experimental compounds for administration.
Use general laboratory equipment, including balances, syringes and needles, blood collection tubes, centrifuges, pipettes, formalin jars, liquid nitrogen, ‑80 freezers, incubators, fluid/syringe pumps, chemical and clean hoods, PPE (lab coat, gloves, face mask or respirator, shoe covers, hair nets, eye protection), quarantine/isolation rooms, autoclaves, necropsy hand tools.
Additional tasks as assigned.
Secondary Responsibilities
Assist PIs and Study Coordinators to ensure study protocol, schedules, formulations, and sample collections are correct and properly communicated to the research team.
Assist Study Coordinators with the creation or verification of cage cards, sample collection prep labels, and data files.
Maintain study‑related forms (e.g. data sheets, health assessments, found dead form, moribund form).
Keep laboratory clean and maintain inventory of all team supplies (media, plates, reagents, surgical tools, etc.) and study‑specific test articles.
Support and participate in other duties and company initiatives as directed.
Utilize various software applications sustained by a Windows platform (Excel, Word, PowerPoint, etc.).
Education & Experience
M.S./B.S./B.A. in science (biology or equivalent; immunology preferred) with 1-3 years of direct animal behavioral work experience, or associate degree with 4 years direct laboratory animal work experience, or 6 years of direct laboratory animal work experience without a college science degree, or equivalent combination of related education and required work experience will be considered with management approval.
AAALAS Certification or commitment to attaining certification.
Preferred animal laboratory research experience with mice and rats, including dosing, in‑life sample collections, and necropsy collections.
Skills & Abilities
Demonstrates a working knowledge and awareness of general laboratory procedures.
Demonstrates an ability to follow detailed instructions, work independently, and in a team environment.
Demonstrates an ability to use a computer software to compile and maintain study data and reports for study records and sample inventory.
Demonstrates a positive attitude and respect for co‑workers, managers, and other employees.
Exhibits a basic understanding of GLP, AAALAC, OLAW, USDA, OHS, PHS, The Guide, and IACUC regulations and standards with consistent application of these practices.
Exhibits accuracy performing laboratory operations.
Exhibits an aptitude for quality, an eye for detail, the ability to follow written instructions and work with a minimum of supervision.
Exhibits good written and oral communication skills and suitable organization skills.
Maintains a commitment to adhere to all safety regulations and procedures.
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