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ByteDance

Research Scientist, Computational Biology (Seed AI-for-Science)

ByteDance, Seattle, Washington, us, 98127

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Overview

Research Scientist, Computational Biology (Seed AI-for-Science). Responsibilities: contribute to building structure-centric, multimodal models for structure prediction, functional modeling, and de novo molecular design. Work with a cross-disciplinary team of ML researchers, computational biologists, and chemists to advance biology and drug discovery. Responsibilities

Collaborate closely with a multidisciplinary team to tackle cutting-edge scientific challenges in molecular modeling. Contribute to the design, training, and optimization of large-scale models for structure prediction across diverse biomolecular systems, addressing challenges such as conformational sampling, binding affinity estimation, and de novo molecular generation. Translate insights from structural biology, experimental data, and physical principles into scalable model architectures and generative algorithms. What We Offer

A collaborative, impact-driven environment at the intersection of biology and AI. Access to cutting-edge compute infrastructure and proprietary tools. Opportunities to contribute to open science and transformative technologies in drug discovery. Qualifications

PhD in Computational Biology, Structural Biology, Computer-Aided Drug Design (CADD), Biophysics, or a related field, with publications in top-tier journals or contributions to widely adopted tools. 1–5 years of industry or postdoctoral experience with a proven track record of applying computational tools in drug discovery or molecular biology. Extensive experience with computational tools and workflows in structural or computational biology, including molecular dynamics (GROMACS, AMBER), docking (AutoDock, Glide), quantum chemistry (ORCA, Gaussian), structure prediction and design (Rosetta, RFDiffusion), or analysis of cryo-EM/X-ray data. Hands-on experience integrating wet-lab and computational data, and applying structural or biological insights to address complex biological problems. Proficiency in programming and scientific computing (Python, C++, bioinformatics pipelines). Strong scientific curiosity, a collaborative mindset, and the ability to quickly learn new concepts and tools. About Us

Founded in 2012, ByteDance's mission is to inspire creativity and enrich life. With a suite of products including TikTok, Lemon8, CapCut and Pico, ByteDance also operates platforms for the China market. We aim to connect, consume, and create content globally. Why Join ByteDance

Our mission is to inspire creativity and enrich life. We build products that help people express themselves, discover, and connect. Our diverse teams collaborate to create value for communities and drive meaningful breakthroughs. Join us. Diversity & Inclusion

ByteDance is committed to creating an inclusive space where employees are valued for their skills, experiences, and perspectives, reflecting the communities we reach. Reasonable Accommodation

ByteDance is committed to providing reasonable accommodations in recruitment processes for candidates with disabilities or other protected reasons. If you need assistance or an accommodation, please reach out to us at https://tinyurl.com/RA-request Job Information

Compensation: The base salary range for this position in the selected city is $177,688 – $341,734 annually. Compensation may vary based on qualifications, skills, and location. Total package may include discretionary bonuses, incentives, and stock units. Benefits vary by location and role; employees have day-one access to medical, dental, and vision insurance, a 401(k) with company match, parental leave, disability coverage, life insurance, wellbeing benefits, and paid time off. The company reserves the right to modify benefits programs at any time. For Los Angeles County (unincorporated) candidates, qualified applicants with arrest or conviction records will be considered in accordance with applicable laws, including the Los Angeles County Fair Chance Ordinance and the California Fair Chance Act. Seniority level

Mid-Senior level Employment type

Full-time Job function

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