Somite AI
Senior / Principal Computational Biologist
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Senior / Principal Computational Biologist
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Somite AI Get AI-powered advice on this job and more exclusive features. About Somite
Somite.ai is a venture-backed company aiming to become the
OpenAI of stem cell biology , developing
AI foundation models
for human stem cells to drive novel cell therapies at scale. We take a full-stack approach—generating data at 1,000x lower cost, training large-scale models with unmatched predictive power, and using these models to discover, refine, and optimize high-impact applications in cell therapy. Our founding team includes repeat AI entrepreneur Dr. Micha Breakstone (Chorus.ai, acquired for $575M), the Head of the Fundamental AI Group at MIT, and three Harvard Medical School professors and National Academy of Sciences/Medicine members, including the Chair of the Genetics Department at HMS. Based in Boston and launching operations in January 2024, Somite has raised close to $60M to date (Forbes). Core Values
We show up – fully accountable, all-in, doing whatever it takes We act with urgency – swift, decisive, proactive We support one another – collaborative, helpful, empathetic Location
Boston, MA (onsite, full-time) About the Role
As a Senior Computational Biologist, you will play a key role in creating pipelines, models and performing research over large scale single cell datasets. This role is ideal for someone who is passionate about large-scale transcriptomic data that will be used to create groundbreaking cell replacement technologies. You will work at the intersection of developmental biological research, data science, and software development, contributing to single-cell and spatial transcriptomics analysis, translating scientific discoveries into cutting edge cell replacement therapies. Responsibilities
Drive new research directions at the interface of bioinformatics and AI-powered stem cell biology Develop and optimize computational biology pipelines for preprocessing, analysis, modeling and interpretation of high-dimensional transcriptomic data Stay at the forefront of computational biology, keeping up with state-of-the-art techniques in developmental biology, single-cell multi-modal analysis and spatial transcriptomics Operate autonomously in a fast-moving startup, helping shape Somite’s computational biology roadmap Mentor and provide technical guidance to team members, fostering collaboration and knowledge sharing across disciplines Collaborate closely with other computational biologists, machine learning researchers, and software engineers to build robust, scalable solutions Qualifications
PhD in Computational Biology, Bioinformatics, Computer Science, or a related field 3+ years of experience analyzing large-scale genomic and transcriptomic datasets, such as single cell RNA-seq and spatial omics Solid computational and statistical skills, with demonstrated experience in high-dimensional biological data analysis Strong programming skills and experience developing robust products, preferably in Python Passion for data-driven biology and its potential to transform healthcare Preferred Qualifications
Strong domain knowledge in developmental biology or stem cell research (highly advantageous) 2+ years of experience in non-academic industry setting Prior experience in a startup or fast-paced environment Experience in machine learning, and developing models over biological data Strong publication record in top journals Benefits
Take a technical leadership role with a mission-driven company with the potential to significantly impact the lives of millions Work alongside a talented and passionate team at the forefront of AI and cellular biology Contribute to the development of groundbreaking therapies that address significant unmet medical needs Enjoy a competitive salary and benefits package, including flexible work options Exceptional Candidates
Exceptional candidates who demonstrate outstanding capabilities and potential will be considered, even if they do not meet every qualification listed. Join us and help unlock the full potential of AI for the benefit of human health!
#J-18808-Ljbffr
Join to apply for the
Senior / Principal Computational Biologist
role at
Somite AI Get AI-powered advice on this job and more exclusive features. About Somite
Somite.ai is a venture-backed company aiming to become the
OpenAI of stem cell biology , developing
AI foundation models
for human stem cells to drive novel cell therapies at scale. We take a full-stack approach—generating data at 1,000x lower cost, training large-scale models with unmatched predictive power, and using these models to discover, refine, and optimize high-impact applications in cell therapy. Our founding team includes repeat AI entrepreneur Dr. Micha Breakstone (Chorus.ai, acquired for $575M), the Head of the Fundamental AI Group at MIT, and three Harvard Medical School professors and National Academy of Sciences/Medicine members, including the Chair of the Genetics Department at HMS. Based in Boston and launching operations in January 2024, Somite has raised close to $60M to date (Forbes). Core Values
We show up – fully accountable, all-in, doing whatever it takes We act with urgency – swift, decisive, proactive We support one another – collaborative, helpful, empathetic Location
Boston, MA (onsite, full-time) About the Role
As a Senior Computational Biologist, you will play a key role in creating pipelines, models and performing research over large scale single cell datasets. This role is ideal for someone who is passionate about large-scale transcriptomic data that will be used to create groundbreaking cell replacement technologies. You will work at the intersection of developmental biological research, data science, and software development, contributing to single-cell and spatial transcriptomics analysis, translating scientific discoveries into cutting edge cell replacement therapies. Responsibilities
Drive new research directions at the interface of bioinformatics and AI-powered stem cell biology Develop and optimize computational biology pipelines for preprocessing, analysis, modeling and interpretation of high-dimensional transcriptomic data Stay at the forefront of computational biology, keeping up with state-of-the-art techniques in developmental biology, single-cell multi-modal analysis and spatial transcriptomics Operate autonomously in a fast-moving startup, helping shape Somite’s computational biology roadmap Mentor and provide technical guidance to team members, fostering collaboration and knowledge sharing across disciplines Collaborate closely with other computational biologists, machine learning researchers, and software engineers to build robust, scalable solutions Qualifications
PhD in Computational Biology, Bioinformatics, Computer Science, or a related field 3+ years of experience analyzing large-scale genomic and transcriptomic datasets, such as single cell RNA-seq and spatial omics Solid computational and statistical skills, with demonstrated experience in high-dimensional biological data analysis Strong programming skills and experience developing robust products, preferably in Python Passion for data-driven biology and its potential to transform healthcare Preferred Qualifications
Strong domain knowledge in developmental biology or stem cell research (highly advantageous) 2+ years of experience in non-academic industry setting Prior experience in a startup or fast-paced environment Experience in machine learning, and developing models over biological data Strong publication record in top journals Benefits
Take a technical leadership role with a mission-driven company with the potential to significantly impact the lives of millions Work alongside a talented and passionate team at the forefront of AI and cellular biology Contribute to the development of groundbreaking therapies that address significant unmet medical needs Enjoy a competitive salary and benefits package, including flexible work options Exceptional Candidates
Exceptional candidates who demonstrate outstanding capabilities and potential will be considered, even if they do not meet every qualification listed. Join us and help unlock the full potential of AI for the benefit of human health!
#J-18808-Ljbffr