Arc Institute
Research Associate II, Pluvinage Lab
Arc Institute, Palo Alto, California, United States, 94306
The Arc Institute is a new scientific institution conducting curiosity-driven basic science and technology development to understand and treat complex human diseases. Headquartered in Palo Alto, California, Arc is an independent research organization founded on the belief that many important research programs will be enabled by new institutional models. Arc operates in partnership with Stanford University, UCSF, and UC Berkeley. While the prevailing university research model has yielded many tremendous successes, we believe in the importance of institutional experimentation as a way to make progress. These include:
Funding: Arc fully funds Core Investigators’ (PIs’) research groups, liberating scientists from the typical constraints of project-based external grants. Technology: Biomedical research has become increasingly dependent on complex tooling. Arc Technology Centers develop, optimize, and deploy rapidly advancing experimental and computational technologies in collaboration with Core Investigators. Support: Arc aims to provide first-class support—operationally, financially, and scientifically—that will enable scientists to pursue long-term high risk, high reward research that can meaningfully advance progress in disease cures, including neurodegeneration, cancer, and immune dysfunction. Culture: We believe that culture matters enormously in science and that excellence is difficult to sustain. We aim to create a culture that is focused on scientific curiosity, a deep commitment to truth, broad ambition, and selfless collaboration.
Arc has scaled to nearly 300 people to date. With $650M+ in committed funding and a state of the art new lab facility in Palo Alto, Arc will continue to grow quickly in the coming years.
About the position We are seeking a Research Associate II to join the Pluvinage Lab at the Arc Institute. Our goal is to improve the lives of patients with neurological diseases. We do this by exploring undiagnosed autoimmunity in rare mystery cases and common neurodegenerative conditions alike. What if we could tune the immune system to promote healthy brain aging?
You will have the opportunity to work with world-leading scientists in the fields of immunology, functional genomics, and computational biology. You will also be exposed to clinical neurology with projects that span basic discovery all the way to translation.
This is a great stepping stone for candidates looking to enroll in a top MD, PhD, or MD/PhD program in the future, as you will be involved in designing projects from the ground up and co-authoring papers. The ideal candidate must have a strong background in molecular biology and will learn to apply their skills to build new tools, design new treatments, and discover new neurobiology.
About you You love science and learning. Whether it’s gaining knowledge in new fields of scientific research or learning a new lab technique, you never stop being curious and routinely enjoy stepping out of your comfort zone to learn new things. You can work fast and are detail-oriented. You are careful and diligent about good documentation practices and keeping things organized while moving at a rapid pace. You explicitly wish to use this experience to gain entry into a MD, PhD, or MD/PhD program. We will help you achieve this goal. You love to collaborate and help others. Science is a team effort, and you pride yourself in taking the initiative to help. You are a problem solver. You pride yourself in your ability to troubleshoot complex problems in the lab.
In this position you will Contribute to the discovery of novel autoantibodies in patients with mysterious neurological diseases and common neurodegenerative conditions Contribute to the design and characterization of targeted immunotherapies Learn and implement high-throughput technologies including phage display, CRISPR screening, single-cell sequencing Assist with research planning, execution, analysis, troubleshooting, and data interpretation with a high degree of independence and continued support from the rest of the team Analyze and present data at group meetings and seminars Maintain an organized and detailed lab notebook
Requirements BS/MS or equivalent professional experience in cell & molecular biology, biochemistry or immunology BS degree, 2+ years of relevant experience or with a MS degree, 0-2+ years of relevant postgraduate experience Candidates with extensive undergraduate research experience are encouraged to apply Extensive experience with standard molecular biology techniques and proficiency with mammalian cell culture Biochemistry experience (protein expression + purification) is a plus Bioinformatics software experience is a plus Highly motivated, curious, and a team player
The base salary for this position is $75,900. This amount does not include benefits or other forms of compensation.
Voluntary Self-Identification For government reporting purposes, we ask candidates to respond to the below self-identification survey. Completion of the form is entirely voluntary. Whatever your decision, it will not be considered in the hiring process or thereafter. Any information that you do provide will be recorded and maintained in a confidential file.
As set forth in Arc Institute’s Equal Employment Opportunity policy, we do not discriminate on the basis of any protected group status under any applicable law.
If you believe you belong to any of the categories of protected veterans listed below, please indicate by making the appropriate selection. As a government contractor subject to VEVRAA, we request this information in order to measure the effectiveness of the outreach and positive recruitment efforts we undertake pursuant to VEVRAA. Classification of protected categories is as follows:
A "disabled veteran" is one of the following: a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or a person who was discharged or released from active duty because of a service-connected disability. A "recently separated veteran" means any veteran during the three-year period beginning on the date of such veteran's discharge or release from active duty in the U.S. military, ground, naval, or air service. An "active duty wartime or campaign badge veteran" means a veteran who served on active duty in the U.S. military, ground, naval or air service during a war, or in a campaign or expedition for which a campaign badge has been authorized under the laws administered by the Department of Defense. An "Armed forces service medal veteran" means a veteran who, while serving on active duty in the U.S. military, ground, naval or air service, participated in a United States military operation for which an Armed Forces service medal was awarded pursuant to Executive Order 12985.
DISABILITY STATUS: Select...
PUBLIC BURDEN STATEMENT: According to the Paperwork Reduction Act of 1995 no persons are required to respond to a collection of information unless such collection displays a valid OMB control number. This survey should take about 5 minutes to complete.
#J-18808-Ljbffr
Funding: Arc fully funds Core Investigators’ (PIs’) research groups, liberating scientists from the typical constraints of project-based external grants. Technology: Biomedical research has become increasingly dependent on complex tooling. Arc Technology Centers develop, optimize, and deploy rapidly advancing experimental and computational technologies in collaboration with Core Investigators. Support: Arc aims to provide first-class support—operationally, financially, and scientifically—that will enable scientists to pursue long-term high risk, high reward research that can meaningfully advance progress in disease cures, including neurodegeneration, cancer, and immune dysfunction. Culture: We believe that culture matters enormously in science and that excellence is difficult to sustain. We aim to create a culture that is focused on scientific curiosity, a deep commitment to truth, broad ambition, and selfless collaboration.
Arc has scaled to nearly 300 people to date. With $650M+ in committed funding and a state of the art new lab facility in Palo Alto, Arc will continue to grow quickly in the coming years.
About the position We are seeking a Research Associate II to join the Pluvinage Lab at the Arc Institute. Our goal is to improve the lives of patients with neurological diseases. We do this by exploring undiagnosed autoimmunity in rare mystery cases and common neurodegenerative conditions alike. What if we could tune the immune system to promote healthy brain aging?
You will have the opportunity to work with world-leading scientists in the fields of immunology, functional genomics, and computational biology. You will also be exposed to clinical neurology with projects that span basic discovery all the way to translation.
This is a great stepping stone for candidates looking to enroll in a top MD, PhD, or MD/PhD program in the future, as you will be involved in designing projects from the ground up and co-authoring papers. The ideal candidate must have a strong background in molecular biology and will learn to apply their skills to build new tools, design new treatments, and discover new neurobiology.
About you You love science and learning. Whether it’s gaining knowledge in new fields of scientific research or learning a new lab technique, you never stop being curious and routinely enjoy stepping out of your comfort zone to learn new things. You can work fast and are detail-oriented. You are careful and diligent about good documentation practices and keeping things organized while moving at a rapid pace. You explicitly wish to use this experience to gain entry into a MD, PhD, or MD/PhD program. We will help you achieve this goal. You love to collaborate and help others. Science is a team effort, and you pride yourself in taking the initiative to help. You are a problem solver. You pride yourself in your ability to troubleshoot complex problems in the lab.
In this position you will Contribute to the discovery of novel autoantibodies in patients with mysterious neurological diseases and common neurodegenerative conditions Contribute to the design and characterization of targeted immunotherapies Learn and implement high-throughput technologies including phage display, CRISPR screening, single-cell sequencing Assist with research planning, execution, analysis, troubleshooting, and data interpretation with a high degree of independence and continued support from the rest of the team Analyze and present data at group meetings and seminars Maintain an organized and detailed lab notebook
Requirements BS/MS or equivalent professional experience in cell & molecular biology, biochemistry or immunology BS degree, 2+ years of relevant experience or with a MS degree, 0-2+ years of relevant postgraduate experience Candidates with extensive undergraduate research experience are encouraged to apply Extensive experience with standard molecular biology techniques and proficiency with mammalian cell culture Biochemistry experience (protein expression + purification) is a plus Bioinformatics software experience is a plus Highly motivated, curious, and a team player
The base salary for this position is $75,900. This amount does not include benefits or other forms of compensation.
Voluntary Self-Identification For government reporting purposes, we ask candidates to respond to the below self-identification survey. Completion of the form is entirely voluntary. Whatever your decision, it will not be considered in the hiring process or thereafter. Any information that you do provide will be recorded and maintained in a confidential file.
As set forth in Arc Institute’s Equal Employment Opportunity policy, we do not discriminate on the basis of any protected group status under any applicable law.
If you believe you belong to any of the categories of protected veterans listed below, please indicate by making the appropriate selection. As a government contractor subject to VEVRAA, we request this information in order to measure the effectiveness of the outreach and positive recruitment efforts we undertake pursuant to VEVRAA. Classification of protected categories is as follows:
A "disabled veteran" is one of the following: a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or a person who was discharged or released from active duty because of a service-connected disability. A "recently separated veteran" means any veteran during the three-year period beginning on the date of such veteran's discharge or release from active duty in the U.S. military, ground, naval, or air service. An "active duty wartime or campaign badge veteran" means a veteran who served on active duty in the U.S. military, ground, naval or air service during a war, or in a campaign or expedition for which a campaign badge has been authorized under the laws administered by the Department of Defense. An "Armed forces service medal veteran" means a veteran who, while serving on active duty in the U.S. military, ground, naval or air service, participated in a United States military operation for which an Armed Forces service medal was awarded pursuant to Executive Order 12985.
DISABILITY STATUS: Select...
PUBLIC BURDEN STATEMENT: According to the Paperwork Reduction Act of 1995 no persons are required to respond to a collection of information unless such collection displays a valid OMB control number. This survey should take about 5 minutes to complete.
#J-18808-Ljbffr