BioSpace
Associate Scientist MSAT (Cell & Gene Therapy) (Contractor)
BioSpace, Trenton, New Jersey, United States
Associate Scientist MSAT (Cell & Gene Therapy) (Contractor)
Legend Biotech is a global biotechnology company dedicated to treating, and one day curing, life‑threatening diseases. Headquartered in Somerset, New Jersey, we develop advanced cell therapies across a range of technology platforms, including autologous and allogenic chimeric antigen receptor T‑cell, T‑cell receptor (TCR‑T), and natural killer (NK) cell‑based immunotherapy. We partner with Janssen, a Johnson & Johnson company, to jointly develop and commercialize the CAR‑T therapy ciltacabtagene autolecuel (cilta‑cel) for multiple myeloma.
Role Overview We are seeking a motivated Associate Scientist to join our MSAT team in Somerset, New Jersey. The role supports development, troubleshooting, and optimization of automated manufacturing processes for CAR‑T and other cell therapy products. Under senior guidance, you will perform bench‑scale experiments, technology evaluations, and process improvement studies, contribute to manufacturing robustness and efficiency, and execute laboratory work, assist in equipment testing, and analyze process data. This position is contract‑based.
Key Responsibilities
Execute bench‑scale experiments for bio‑pilot run comparisons, technology evaluations, and process improvement initiatives.
Operate and assist in troubleshooting closed‑system and automated platforms (e.g., Prodigy, Rotea, Cue, Lovo, G‑Rex).
Perform and support analytical assays such as flow cytometry, qPCR, ELISA, and cell counting to evaluate product quality and process outcomes.
Collect, analyze, and summarize experimental data (cell growth, viability, metabolite trends) using statistical tools.
Support preparation of study protocols, technical reports, and SOPs in compliance with GMP standards.
Assist in process troubleshooting and root‑cause investigations for manufacturing and automation systems.
Maintain a safe, organized, and compliant laboratory workspace.
Make independent decisions regarding routine laboratory execution, minor troubleshooting, and data analysis within approved study protocols, seeking guidance for major decisions and changes to validated processes.
Requirements
Bachelor’s degree in biotechnology, bioengineering, molecular biology, or related discipline.
1–2 years of hands‑on cell culture (T‑cells, immune cells, or primary cells) experience in academic, process development, or GMP labs.
Hands‑on experience with aseptic technique and biosafety cabinet work.
Experience in basic analytical methods such as cell counting, viability assays, and metabolite monitoring.
Familiarity with data analysis and preparation of technical documentation.
Exposure to automated/closed‑system platforms preferred.
Strong organizational and documentation skills.
Proficiency with Microsoft Office (Excel, Word, PowerPoint).
Basic data analysis using Excel, JMP, or similar tools.
Ability to interface with instrument control software.
Benefits We are committed to creating a workplace where employees can thrive professionally and personally. Our comprehensive benefits package includes medical, dental, and vision insurance, a 401(k) retirement plan with company match vesting fully on day one, equity and stock options for eligible roles, eight weeks of paid parental leave after three months, a paid time off policy (15 vacation days, 5 personal days, 5 sick days, 11 U.S. national holidays, and 3 floating holidays), flexible spending and health savings accounts, life and AD&D insurance, short‑ and long‑term disability coverage, legal assistance, supplemental plans (pet, critical illness, accident, hospital indemnity), commuter benefits, family planning resources, well‑being initiatives, and peer‑to‑peer recognition programs.
EEO Statement Legend Biotech is a proud equal‑opportunity/affirmative action employer committed to attracting, retaining, and maximizing the performance of a diverse and inclusive workforce. We ensure equal employment opportunity without discrimination or harassment based on race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity or expression, age, disability, national origin, marital or domestic/civil partnership status, genetic information, citizenship status, military or veteran status, or any other characteristic protected by applicable law.
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Role Overview We are seeking a motivated Associate Scientist to join our MSAT team in Somerset, New Jersey. The role supports development, troubleshooting, and optimization of automated manufacturing processes for CAR‑T and other cell therapy products. Under senior guidance, you will perform bench‑scale experiments, technology evaluations, and process improvement studies, contribute to manufacturing robustness and efficiency, and execute laboratory work, assist in equipment testing, and analyze process data. This position is contract‑based.
Key Responsibilities
Execute bench‑scale experiments for bio‑pilot run comparisons, technology evaluations, and process improvement initiatives.
Operate and assist in troubleshooting closed‑system and automated platforms (e.g., Prodigy, Rotea, Cue, Lovo, G‑Rex).
Perform and support analytical assays such as flow cytometry, qPCR, ELISA, and cell counting to evaluate product quality and process outcomes.
Collect, analyze, and summarize experimental data (cell growth, viability, metabolite trends) using statistical tools.
Support preparation of study protocols, technical reports, and SOPs in compliance with GMP standards.
Assist in process troubleshooting and root‑cause investigations for manufacturing and automation systems.
Maintain a safe, organized, and compliant laboratory workspace.
Make independent decisions regarding routine laboratory execution, minor troubleshooting, and data analysis within approved study protocols, seeking guidance for major decisions and changes to validated processes.
Requirements
Bachelor’s degree in biotechnology, bioengineering, molecular biology, or related discipline.
1–2 years of hands‑on cell culture (T‑cells, immune cells, or primary cells) experience in academic, process development, or GMP labs.
Hands‑on experience with aseptic technique and biosafety cabinet work.
Experience in basic analytical methods such as cell counting, viability assays, and metabolite monitoring.
Familiarity with data analysis and preparation of technical documentation.
Exposure to automated/closed‑system platforms preferred.
Strong organizational and documentation skills.
Proficiency with Microsoft Office (Excel, Word, PowerPoint).
Basic data analysis using Excel, JMP, or similar tools.
Ability to interface with instrument control software.
Benefits We are committed to creating a workplace where employees can thrive professionally and personally. Our comprehensive benefits package includes medical, dental, and vision insurance, a 401(k) retirement plan with company match vesting fully on day one, equity and stock options for eligible roles, eight weeks of paid parental leave after three months, a paid time off policy (15 vacation days, 5 personal days, 5 sick days, 11 U.S. national holidays, and 3 floating holidays), flexible spending and health savings accounts, life and AD&D insurance, short‑ and long‑term disability coverage, legal assistance, supplemental plans (pet, critical illness, accident, hospital indemnity), commuter benefits, family planning resources, well‑being initiatives, and peer‑to‑peer recognition programs.
EEO Statement Legend Biotech is a proud equal‑opportunity/affirmative action employer committed to attracting, retaining, and maximizing the performance of a diverse and inclusive workforce. We ensure equal employment opportunity without discrimination or harassment based on race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity or expression, age, disability, national origin, marital or domestic/civil partnership status, genetic information, citizenship status, military or veteran status, or any other characteristic protected by applicable law.
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