Inside Higher Ed
Position Overview
Job Title: Post Doctoral Scholar
Department: CCC | Sponsored Research
Position Title: Postdoctoral Fellow in Metabolism and Cancer
Description:
We are seeking highly motivated and enthusiastic Ph.D. or MD scientists to join our group as postdoctoral research fellows.
Position Description:
The Sen Lab invites applications for a postdoctoral research fellow position in cancer metabolism. Our research aims to define metabolic vulnerabilities in lung cancer and their impact on tumor progression and therapy resistance. This position is supported by a newly funded NIH grant.
Lab Focus The Sen Lab focuses on the development of new treatment paradigms for clinically relevant molecular subsets of lung cancer, the leading cause of cancer mortality. Situated Comprehensive Cancer Center at the Ohio State University Wexner Medical Center, the Sen Lab takes an interdisciplinary approach to studying basic mechanisms and biological principles of tumor pathogenesis with a focus on lung cancer. We aim to elucidate the fundamental principles of cancer initiation, progression, and therapeutic response and resistance and to translate these findings to improve patient outcomes. The overall goal of this research program—spanning basic mechanistic discoveries, application of high-throughput technologies, validation in cancer-relevant mouse models, and translation platforms—is to understand the fundamental principles driving tumor progression, including both cancer cell-intrinsic signaling and contributions from the tumor microenvironment, to improve therapy and survival outcomes in lung cancer patients.
Responsibilities
Conduct independent research on cancer metabolism and therapeutic targeting
Utilize stable isotope tracing and metabolomics to investigate metabolic dependencies
Perform experiments in genetically engineered mouse models of lung cancer
Collaborate with multidisciplinary teams within and beyond home institution
Collaborate with bioinformaticians and clinicians for translational studies
Write scientific manuscripts describing research findings
Attend national and international meetings to present research findings, learn about the latest advances in the field, and develop a scientific network
Apply for fellowships and grants
Mentor junior scientists
Qualifications
Ph.D. or MD/Ph.D. in biochemistry, cancer biology, or metabolism
Expertise in mass spectrometry, lipidomics, and metabolic flux analysis
Established experience with animal models is mandatory
Strong publication record, including at least two publication outputs in the last three years, with the applicant as the principal author of at least one publication
Self-motivation and a curiosity-driven mindset
Prior postdoctoral experience is not required
Requires successful completion of a background check.
The selected candidate may be requested to complete a pre-employment physical including a drug screen.
Additional Information The Ohio State University
is a dynamic community of diverse resources, where opportunity thrives and where individuals transform themselves and the world.
The Ohio State University
is one of the nation’s largest and most comprehensive public universities and a top employer in Ohio. As one of only 57 designated comprehensive cancer centers in the nation,
The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital
and
Richard J. Solove Research Institute
is dedicated to the creation of knowledge in laboratory, clinical and population-based cancer research. We apply those discoveries to develop more effective approaches to cancer prevention, diagnosis, and therapies – providing tomorrow’s standard of care today. A Cancer-Free World Begins Here. The OSUCCC – James is the only cancer program in the United States that features a National Cancer Institute (NCI)-designated comprehensive cancer center aligned with a nationally ranked academic medical center and a freestanding cancer hospital on the campus of one of the nation’s largest public universities.
Location Biomedical Research Tower (0112)
Position Type Term (Fixed Term)
Scheduled Hours 40
Shift First Shift
Background Check Final candidates are subject to successful completion of a background check. A drug screen or physical may be required during the post offer process.
Equal Opportunity Statement The university is an equal opportunity employer, including veterans and disability. As required by Ohio Revised Code section 3345.0216, Ohio State will: educate students by means of free, open and rigorous intellectual inquiry to seek the truth; equip students with the opportunity to develop intellectual skills to reach their own, informed conclusions; not require, favor, disfavor or prohibit speech or lawful assembly; create a community dedicated to an ethic of civil and free inquiry, which respects the autonomy of each member, supports individual capacities for growth and tolerates differences in opinion; treat all faculty, staff and students as individuals, hold them to equal standards and provide equality of opportunity with regard to race, ethnicity, religion, sex, sexual orientation, gender identity or gender expression.
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Department: CCC | Sponsored Research
Position Title: Postdoctoral Fellow in Metabolism and Cancer
Description:
We are seeking highly motivated and enthusiastic Ph.D. or MD scientists to join our group as postdoctoral research fellows.
Position Description:
The Sen Lab invites applications for a postdoctoral research fellow position in cancer metabolism. Our research aims to define metabolic vulnerabilities in lung cancer and their impact on tumor progression and therapy resistance. This position is supported by a newly funded NIH grant.
Lab Focus The Sen Lab focuses on the development of new treatment paradigms for clinically relevant molecular subsets of lung cancer, the leading cause of cancer mortality. Situated Comprehensive Cancer Center at the Ohio State University Wexner Medical Center, the Sen Lab takes an interdisciplinary approach to studying basic mechanisms and biological principles of tumor pathogenesis with a focus on lung cancer. We aim to elucidate the fundamental principles of cancer initiation, progression, and therapeutic response and resistance and to translate these findings to improve patient outcomes. The overall goal of this research program—spanning basic mechanistic discoveries, application of high-throughput technologies, validation in cancer-relevant mouse models, and translation platforms—is to understand the fundamental principles driving tumor progression, including both cancer cell-intrinsic signaling and contributions from the tumor microenvironment, to improve therapy and survival outcomes in lung cancer patients.
Responsibilities
Conduct independent research on cancer metabolism and therapeutic targeting
Utilize stable isotope tracing and metabolomics to investigate metabolic dependencies
Perform experiments in genetically engineered mouse models of lung cancer
Collaborate with multidisciplinary teams within and beyond home institution
Collaborate with bioinformaticians and clinicians for translational studies
Write scientific manuscripts describing research findings
Attend national and international meetings to present research findings, learn about the latest advances in the field, and develop a scientific network
Apply for fellowships and grants
Mentor junior scientists
Qualifications
Ph.D. or MD/Ph.D. in biochemistry, cancer biology, or metabolism
Expertise in mass spectrometry, lipidomics, and metabolic flux analysis
Established experience with animal models is mandatory
Strong publication record, including at least two publication outputs in the last three years, with the applicant as the principal author of at least one publication
Self-motivation and a curiosity-driven mindset
Prior postdoctoral experience is not required
Requires successful completion of a background check.
The selected candidate may be requested to complete a pre-employment physical including a drug screen.
Additional Information The Ohio State University
is a dynamic community of diverse resources, where opportunity thrives and where individuals transform themselves and the world.
The Ohio State University
is one of the nation’s largest and most comprehensive public universities and a top employer in Ohio. As one of only 57 designated comprehensive cancer centers in the nation,
The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital
and
Richard J. Solove Research Institute
is dedicated to the creation of knowledge in laboratory, clinical and population-based cancer research. We apply those discoveries to develop more effective approaches to cancer prevention, diagnosis, and therapies – providing tomorrow’s standard of care today. A Cancer-Free World Begins Here. The OSUCCC – James is the only cancer program in the United States that features a National Cancer Institute (NCI)-designated comprehensive cancer center aligned with a nationally ranked academic medical center and a freestanding cancer hospital on the campus of one of the nation’s largest public universities.
Location Biomedical Research Tower (0112)
Position Type Term (Fixed Term)
Scheduled Hours 40
Shift First Shift
Background Check Final candidates are subject to successful completion of a background check. A drug screen or physical may be required during the post offer process.
Equal Opportunity Statement The university is an equal opportunity employer, including veterans and disability. As required by Ohio Revised Code section 3345.0216, Ohio State will: educate students by means of free, open and rigorous intellectual inquiry to seek the truth; equip students with the opportunity to develop intellectual skills to reach their own, informed conclusions; not require, favor, disfavor or prohibit speech or lawful assembly; create a community dedicated to an ethic of civil and free inquiry, which respects the autonomy of each member, supports individual capacities for growth and tolerates differences in opinion; treat all faculty, staff and students as individuals, hold them to equal standards and provide equality of opportunity with regard to race, ethnicity, religion, sex, sexual orientation, gender identity or gender expression.
#J-18808-Ljbffr