The Ohio State University Wexner Medical Center
Research Senior Technician
The Ohio State University Wexner Medical Center, Columbus, Ohio, United States, 43224
Position Overview:
The lab of Dr. Burns is seeking a highly motivated individual to join his lab as a Research Senior Technician to focus on maintaining colonies, including breeding, and performing mouse experiments such as subcutaneous (SQ) injection of cells, intraperitoneal (IP) injections, oral gavage, and ideally tail vein and intracardiac injections. This position will also perform basic molecular techniques, including plasmid preps, gel electrophoresis, potential western blotting and cell culture. Studies will be conducted through in vitro, ex vivo and in vivo systems as well as with patient samples.
Responsibilities
Perform molecular biology techniques, ex vivo and in vivo (mouse) studies to develop targeted approaches to overcome resistance to targeted therapies in oncogene‑driven lung cancer and develop targeted approaches for the treatment of brain metastases, with the goal of translating these findings to clinical trials for NSCLC.
Maintain animal colony and implement breeding schemas as directed.
Support senior staff in molecular biology techniques, ex vivo and in vivo (mouse) studies.
Document, analyze and interpret data for presentations, manuscripts, grant requirements (current or new), etc.
Participate in TORCH lab meetings, journal clubs and other relevant university oncology or immunotherapy meetings.
Education and Experience
Bachelor’s degree in biology, biological sciences, or related field and/or an equivalent combination of education and experience.
Experience in molecular biology techniques and in vivo work with mouse models is required.
Requires successful completion of a background check; qualified candidates may be asked to complete a pre‑employment physical including a drug screen.
Desired Experience (Preferred But Not Required)
Previous experience working with animals and maintaining colonies.
Specifically, 5‑6 years’ experience in cancer biology and/or metabolism preferred.
Commitment and Teamwork
A strong willingness to work in a team environment is essential.
Contribute to TORCH with both expertise and insight into development of collaborative projects, improving upon and troubleshooting current projects.
Final Note: We strive to end cancer while enhancing and prolonging the lives of lung cancer patients.
Function: Research and Scholarship Subfunction: Research Career Band: Individual Contributor – Technical Career Level: T3
The Ohio State University is a dynamic community of diverse resources, where opportunity thrives and where individuals transform themselves and the world. The Ohio State University is one of the nation’s largest and most comprehensive public universities and a top employer in Ohio. As one of only 57 designated comprehensive cancer centers in the nation, The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute is dedicated to the creation of knowledge in laboratory, clinical and population‑based cancer research. We apply those discoveries to develop more effective approaches to cancer prevention, diagnosis, and therapies – providing tomorrow’s standard of care today. A Cancer‑Free World Begins Here.
Screen reader users may encounter difficulty with the online application. For assistance with applying, please contact hr-accessibleapplication@osu.edu. If you have questions while submitting an application, please review these frequently asked questions. Thank you for your interest in working at Ohio State.
Final candidates are subject to successful completion of a background check. A drug screen or physical may be required during the post‑offer process.
The university is an equal opportunity employer, including veterans and disability.
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The lab of Dr. Burns is seeking a highly motivated individual to join his lab as a Research Senior Technician to focus on maintaining colonies, including breeding, and performing mouse experiments such as subcutaneous (SQ) injection of cells, intraperitoneal (IP) injections, oral gavage, and ideally tail vein and intracardiac injections. This position will also perform basic molecular techniques, including plasmid preps, gel electrophoresis, potential western blotting and cell culture. Studies will be conducted through in vitro, ex vivo and in vivo systems as well as with patient samples.
Responsibilities
Perform molecular biology techniques, ex vivo and in vivo (mouse) studies to develop targeted approaches to overcome resistance to targeted therapies in oncogene‑driven lung cancer and develop targeted approaches for the treatment of brain metastases, with the goal of translating these findings to clinical trials for NSCLC.
Maintain animal colony and implement breeding schemas as directed.
Support senior staff in molecular biology techniques, ex vivo and in vivo (mouse) studies.
Document, analyze and interpret data for presentations, manuscripts, grant requirements (current or new), etc.
Participate in TORCH lab meetings, journal clubs and other relevant university oncology or immunotherapy meetings.
Education and Experience
Bachelor’s degree in biology, biological sciences, or related field and/or an equivalent combination of education and experience.
Experience in molecular biology techniques and in vivo work with mouse models is required.
Requires successful completion of a background check; qualified candidates may be asked to complete a pre‑employment physical including a drug screen.
Desired Experience (Preferred But Not Required)
Previous experience working with animals and maintaining colonies.
Specifically, 5‑6 years’ experience in cancer biology and/or metabolism preferred.
Commitment and Teamwork
A strong willingness to work in a team environment is essential.
Contribute to TORCH with both expertise and insight into development of collaborative projects, improving upon and troubleshooting current projects.
Final Note: We strive to end cancer while enhancing and prolonging the lives of lung cancer patients.
Function: Research and Scholarship Subfunction: Research Career Band: Individual Contributor – Technical Career Level: T3
The Ohio State University is a dynamic community of diverse resources, where opportunity thrives and where individuals transform themselves and the world. The Ohio State University is one of the nation’s largest and most comprehensive public universities and a top employer in Ohio. As one of only 57 designated comprehensive cancer centers in the nation, The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute is dedicated to the creation of knowledge in laboratory, clinical and population‑based cancer research. We apply those discoveries to develop more effective approaches to cancer prevention, diagnosis, and therapies – providing tomorrow’s standard of care today. A Cancer‑Free World Begins Here.
Screen reader users may encounter difficulty with the online application. For assistance with applying, please contact hr-accessibleapplication@osu.edu. If you have questions while submitting an application, please review these frequently asked questions. Thank you for your interest in working at Ohio State.
Final candidates are subject to successful completion of a background check. A drug screen or physical may be required during the post‑offer process.
The university is an equal opportunity employer, including veterans and disability.
#J-18808-Ljbffr