University of Colorado Anschutz Medical Campus
Research Services Professional (Open Rank: Entry - Principal)
University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States, 80012
University of Colorado Anschutz Medical Campus
Department: Biochemistry & Molecular Genetics
Job Title Research Services Professional (Open Rank: Entry - Principal)
Job Summary The primary duties of this full-time position will be to perform molecular biology, biochemistry and/or structural biology, and cell culture experiments designed to elucidate the molecular mechanisms of pre-mRNA splicing and its role in disease, as well as the structure and function of the Six1/Eya transcriptional complex for anti-cancer drug design. This description is a summary only and is describing the general level of work being performed, it is not intended to be all-inclusive. The duties of this position may change from time to time and/or based on business need. We reserve the right to add or delete duties and responsibilities at the discretion of the supervisor and/or hiring authority.
Key Responsibilities
Molecular biology experiments including sub-cloning and mutagenesis
Protein and/or RNA expression and purification
Biochemical and biophysical analyses of protein/protein interaction and/or enzyme function
Mammalian cell culture experiments
Evaluate small molecule compounds in biochemical and cell culture experiments
If interested, the PRA can learn to prepare EM grids, collect data and determine the cryo-EM structure of protein or protein-RNA complexes
Assistance in basic operation of lab, including preparation of solutions and autoclaving material
Work Location: Onsite - this role is expected to work onsite and is located in Aurora, CO.
Why Join Us Our department conducts research across a wide biological scale for fundamental scientific understanding with applications to many disease contexts. The overarching goal is to reach a level of molecular insight that helps develop therapeutic approaches to disease.
As biochemists and molecular geneticists, we are amid an unprecedented time of discovery - our conception of the molecular biology of cells is going from the equivalent of grainy black-and-white to high-resolution technicolor. From deciphering the choreography of transcription complexes, chromosomes, and RNA molecules within cells to developing novel approaches to 3D molecular structure determination to understanding how viruses hijack a cell’s machinery and alter its metabolome, the researchers in Biochemistry and Molecular Genetics (BMG) are at the forefronts of their fields both conceptually and technologically.
Benefits We have AMAZING benefits and offer exceptional amounts of holiday, vacation and sick leave! The University of Colorado offers an excellent benefits package including:
Medical: Multiple plan options
Dental: Multiple plan options
Additional Insurance: Disability, Life, Vision
Retirement 401(a) Plan: Employer contributes 10% of your gross pay
Paid Time Off: Accruals over the year
Vacation Days: 22/year (maximum accrual 352 hours)
Sick Days: 15/year (unlimited maximum accrual)
Holiday Days: 10/year
Tuition Benefit: Employees have access to this benefit on all CU campuses
ECO Pass: Reduced rate RTD Bus and light rail service
There are many additional perks & programs with the CU Advantage.
Qualifications Minimum Qualifications Entry Professional
Bachelor's degree in chemistry, biology, molecular biology or a related field
A combination of education and related technical/paraprofessional experience may be substituted for the bachelor's degree on a year for year basis
Intermediate Professional
Bachelor's degree in chemistry, biology, molecular biology or a related field
A combination of education and related technical/paraprofessional experience may be substituted for the bachelor's degree on a year for year basis
One (1) year professional level research experience
Senior Professional
Bachelor's degree in biology, molecular biology, chemistry, genetics or related field
A combination of education and related technical/paraprofessional experience may be substituted for the bachelor's degree on a year for year basis
Two (2) years professional level research experience
Principal Professional
Bachelor's degree in biology, molecular biology, chemistry, genetics or related field
A combination of education and related technical/paraprofessional experience may be substituted for the bachelor's degree on a year for year basis
Three (3) years professional level research experience
Required: Applicants must meet minimum qualifications at the time of hire.
Preferred Qualifications Master's degree in biology, molecular biology, chemistry, genetics or related field
One (1) to Two (2) years experience or background within an experimental or wet lab
Prior experience in analytical chemistry, especially ultra-high pressure liquid chromatography coupled to mass spectrometry
Competencies, Knowledge, Skills, and Abilities Entry Professional
Knowledge of basic laboratory techniques including safety procedures and techniques
Ability to communicate effectively, both in writing and orally
Ability to establish and maintain effective working relationships with employees at all levels throughout the institution
Outstanding facility user service skills
Demonstrated commitment and leadership ability to advance diversity and inclusion
Ability to interpret and master complex research protocol information
Intermediate Professional
Proficient knowledge of basic laboratory techniques including safety procedures and techniques
Ability to communicate effectively, both in writing and orally
Ability to establish and maintain effective working relationships with employees at all levels throughout the institution
Outstanding facility user service skills
Demonstrated commitment and leadership ability to advance diversity and inclusion
Ability to interpret and master complex research protocol information
Senior Professional
Advanced knowledge of laboratory techniques including safety procedures and techniques
Ability to communicate effectively, both in writing and orally
Ability to establish and maintain effective working relationships with employees at all levels throughout the institution
Outstanding facility user service skills
Demonstrated commitment and leadership ability to advance diversity and inclusion
Ability to interpret and master complex research protocol information
Principal Professional
Expert knowledge of laboratory techniques including safety procedures and techniques
Expert ability to analyze and solve complex problems
Ability to communicate effectively, both in writing and orally
Ability to establish and maintain working relationships with employees at all levels throughout the institution
Outstanding facility user service skills
Demonstrated commitment and leadership ability to advance diversity and inclusion
Ability to interpret and master complex research protocol information
Higher-level knowledge of Structural Biology, Instrumentation, and Computational Biology processes, functions and/or technology
How to Apply For full consideration, please submit the following document(s):
A letter of interest describing relevant job experiences as they relate to listed job qualifications and interest in the position
Curriculum vitae / Resume
Three to five professional references, including name, address, phone number (mobile number if appropriate), and email address
Questions should be directed to: Rui Zhao, rui.zhao@cuanschutz.edu
Screening of Applications Begins Applications will be accepted until finalists are identified, but preference will be given to complete applications received by
November 15, 2025.
Those who do not apply by this date may or may not be considered.
Anticipated Pay Range
Entry Professional: $46,274 - $58,861
Intermediate Professional: $50,357 - $64,054
Senior Professional: $54,440 - $69,248
Principal Professional: $62,606 - $79,635
The above salary range (or hiring range) represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting. This position may be eligible for overtime compensation, depending on the level.
Your total compensation goes beyond the number on your paycheck. The University of Colorado provides generous leave, health plans and retirement contributions that add to your bottom line.
Total Compensation Calculator
Equal Employment Opportunity Statement CU is an Equal Opportunity Employer and complies with all applicable federal, state, and local laws governing nondiscrimination in employment. We are committed to creating a workplace where all individuals are treated with respect and dignity, and we encourage individuals from all backgrounds to apply, including protected veterans and individuals with disabilities.
ADA Statement The University will provide reasonable accommodations to applicants with disabilities throughout the employment application process. To request an accommodation pursuant to the Americans with Disabilities Act, please contact the Human Resources ADA Coordinator at hr.adacoordinator@cuanschutz.edu.
Background Check Statement The University of Colorado Anschutz Medical Campus is dedicated to ensuring a safe and secure environment for our faculty, staff, students and visitors. To assist in achieving that goal, we conduct background investigations for all prospective employees.
Vaccination Statement CU Anschutz strongly encourages vaccination against the COVID-19 virus and other vaccine preventable diseases. If you work, visit, or volunteer in healthcare facilities or clinics operated by our affiliated hospital or clinical partners or by CU Anschutz, you will be required to comply with the vaccination and medical surveillance policies of the facilities or clinics where you work, visit, or volunteer, respectively. In addition, if you work in certain research areas or perform certain safety sensitive job duties, you must enroll in the occupational health medical surveillance program.
Application Materials Required Cover Letter, Resume/CV, List of References
Job Category Research Services
Primary Location Aurora
Department U0001 -- Anschutz Med Campus or Denver - 20085 - SOM-BioChem&Molecular Genetics
Schedule Full-time
Posting Date Nov 7, 2025
Unposting Date Ongoing
Posting Contact Name Rui Zhao
Posting Contact Email rui.zhao@cuanschutz.edu
Position Number 00827369
#J-18808-Ljbffr
Job Title Research Services Professional (Open Rank: Entry - Principal)
Job Summary The primary duties of this full-time position will be to perform molecular biology, biochemistry and/or structural biology, and cell culture experiments designed to elucidate the molecular mechanisms of pre-mRNA splicing and its role in disease, as well as the structure and function of the Six1/Eya transcriptional complex for anti-cancer drug design. This description is a summary only and is describing the general level of work being performed, it is not intended to be all-inclusive. The duties of this position may change from time to time and/or based on business need. We reserve the right to add or delete duties and responsibilities at the discretion of the supervisor and/or hiring authority.
Key Responsibilities
Molecular biology experiments including sub-cloning and mutagenesis
Protein and/or RNA expression and purification
Biochemical and biophysical analyses of protein/protein interaction and/or enzyme function
Mammalian cell culture experiments
Evaluate small molecule compounds in biochemical and cell culture experiments
If interested, the PRA can learn to prepare EM grids, collect data and determine the cryo-EM structure of protein or protein-RNA complexes
Assistance in basic operation of lab, including preparation of solutions and autoclaving material
Work Location: Onsite - this role is expected to work onsite and is located in Aurora, CO.
Why Join Us Our department conducts research across a wide biological scale for fundamental scientific understanding with applications to many disease contexts. The overarching goal is to reach a level of molecular insight that helps develop therapeutic approaches to disease.
As biochemists and molecular geneticists, we are amid an unprecedented time of discovery - our conception of the molecular biology of cells is going from the equivalent of grainy black-and-white to high-resolution technicolor. From deciphering the choreography of transcription complexes, chromosomes, and RNA molecules within cells to developing novel approaches to 3D molecular structure determination to understanding how viruses hijack a cell’s machinery and alter its metabolome, the researchers in Biochemistry and Molecular Genetics (BMG) are at the forefronts of their fields both conceptually and technologically.
Benefits We have AMAZING benefits and offer exceptional amounts of holiday, vacation and sick leave! The University of Colorado offers an excellent benefits package including:
Medical: Multiple plan options
Dental: Multiple plan options
Additional Insurance: Disability, Life, Vision
Retirement 401(a) Plan: Employer contributes 10% of your gross pay
Paid Time Off: Accruals over the year
Vacation Days: 22/year (maximum accrual 352 hours)
Sick Days: 15/year (unlimited maximum accrual)
Holiday Days: 10/year
Tuition Benefit: Employees have access to this benefit on all CU campuses
ECO Pass: Reduced rate RTD Bus and light rail service
There are many additional perks & programs with the CU Advantage.
Qualifications Minimum Qualifications Entry Professional
Bachelor's degree in chemistry, biology, molecular biology or a related field
A combination of education and related technical/paraprofessional experience may be substituted for the bachelor's degree on a year for year basis
Intermediate Professional
Bachelor's degree in chemistry, biology, molecular biology or a related field
A combination of education and related technical/paraprofessional experience may be substituted for the bachelor's degree on a year for year basis
One (1) year professional level research experience
Senior Professional
Bachelor's degree in biology, molecular biology, chemistry, genetics or related field
A combination of education and related technical/paraprofessional experience may be substituted for the bachelor's degree on a year for year basis
Two (2) years professional level research experience
Principal Professional
Bachelor's degree in biology, molecular biology, chemistry, genetics or related field
A combination of education and related technical/paraprofessional experience may be substituted for the bachelor's degree on a year for year basis
Three (3) years professional level research experience
Required: Applicants must meet minimum qualifications at the time of hire.
Preferred Qualifications Master's degree in biology, molecular biology, chemistry, genetics or related field
One (1) to Two (2) years experience or background within an experimental or wet lab
Prior experience in analytical chemistry, especially ultra-high pressure liquid chromatography coupled to mass spectrometry
Competencies, Knowledge, Skills, and Abilities Entry Professional
Knowledge of basic laboratory techniques including safety procedures and techniques
Ability to communicate effectively, both in writing and orally
Ability to establish and maintain effective working relationships with employees at all levels throughout the institution
Outstanding facility user service skills
Demonstrated commitment and leadership ability to advance diversity and inclusion
Ability to interpret and master complex research protocol information
Intermediate Professional
Proficient knowledge of basic laboratory techniques including safety procedures and techniques
Ability to communicate effectively, both in writing and orally
Ability to establish and maintain effective working relationships with employees at all levels throughout the institution
Outstanding facility user service skills
Demonstrated commitment and leadership ability to advance diversity and inclusion
Ability to interpret and master complex research protocol information
Senior Professional
Advanced knowledge of laboratory techniques including safety procedures and techniques
Ability to communicate effectively, both in writing and orally
Ability to establish and maintain effective working relationships with employees at all levels throughout the institution
Outstanding facility user service skills
Demonstrated commitment and leadership ability to advance diversity and inclusion
Ability to interpret and master complex research protocol information
Principal Professional
Expert knowledge of laboratory techniques including safety procedures and techniques
Expert ability to analyze and solve complex problems
Ability to communicate effectively, both in writing and orally
Ability to establish and maintain working relationships with employees at all levels throughout the institution
Outstanding facility user service skills
Demonstrated commitment and leadership ability to advance diversity and inclusion
Ability to interpret and master complex research protocol information
Higher-level knowledge of Structural Biology, Instrumentation, and Computational Biology processes, functions and/or technology
How to Apply For full consideration, please submit the following document(s):
A letter of interest describing relevant job experiences as they relate to listed job qualifications and interest in the position
Curriculum vitae / Resume
Three to five professional references, including name, address, phone number (mobile number if appropriate), and email address
Questions should be directed to: Rui Zhao, rui.zhao@cuanschutz.edu
Screening of Applications Begins Applications will be accepted until finalists are identified, but preference will be given to complete applications received by
November 15, 2025.
Those who do not apply by this date may or may not be considered.
Anticipated Pay Range
Entry Professional: $46,274 - $58,861
Intermediate Professional: $50,357 - $64,054
Senior Professional: $54,440 - $69,248
Principal Professional: $62,606 - $79,635
The above salary range (or hiring range) represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting. This position may be eligible for overtime compensation, depending on the level.
Your total compensation goes beyond the number on your paycheck. The University of Colorado provides generous leave, health plans and retirement contributions that add to your bottom line.
Total Compensation Calculator
Equal Employment Opportunity Statement CU is an Equal Opportunity Employer and complies with all applicable federal, state, and local laws governing nondiscrimination in employment. We are committed to creating a workplace where all individuals are treated with respect and dignity, and we encourage individuals from all backgrounds to apply, including protected veterans and individuals with disabilities.
ADA Statement The University will provide reasonable accommodations to applicants with disabilities throughout the employment application process. To request an accommodation pursuant to the Americans with Disabilities Act, please contact the Human Resources ADA Coordinator at hr.adacoordinator@cuanschutz.edu.
Background Check Statement The University of Colorado Anschutz Medical Campus is dedicated to ensuring a safe and secure environment for our faculty, staff, students and visitors. To assist in achieving that goal, we conduct background investigations for all prospective employees.
Vaccination Statement CU Anschutz strongly encourages vaccination against the COVID-19 virus and other vaccine preventable diseases. If you work, visit, or volunteer in healthcare facilities or clinics operated by our affiliated hospital or clinical partners or by CU Anschutz, you will be required to comply with the vaccination and medical surveillance policies of the facilities or clinics where you work, visit, or volunteer, respectively. In addition, if you work in certain research areas or perform certain safety sensitive job duties, you must enroll in the occupational health medical surveillance program.
Application Materials Required Cover Letter, Resume/CV, List of References
Job Category Research Services
Primary Location Aurora
Department U0001 -- Anschutz Med Campus or Denver - 20085 - SOM-BioChem&Molecular Genetics
Schedule Full-time
Posting Date Nov 7, 2025
Unposting Date Ongoing
Posting Contact Name Rui Zhao
Posting Contact Email rui.zhao@cuanschutz.edu
Position Number 00827369
#J-18808-Ljbffr