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Mount Sinai Health System

Core Research Associate II- Shared Research Resources

Mount Sinai Health System, New York, New York, us, 10261

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Core Research Associate II- Shared Research Resources

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Mount Sinai Health System

Description The Core Research Associate II in the Transgenic and Genome Editing Core will be responsible for tasks related to creation, validation, and cryopreservation of genetically engineered mouse models (GEMMs). The role includes preparation of gene editing reagents, embryo production/manipulation, implantation, post‑operative care, genotyping, breeding, and husbandry support in partnership with the Center for Comparative Medicine and Surgery (CCMS). Experience with rodent survival surgery and embryo handling is preferred but not required.

Responsibilities

Produce mouse embryos via superovulation or natural.

Collect and manipulate pre‑implantation mouse embryos.

Surgically transfer embryos into pseudopregnant mice and provide post‑operative care.

Manage mouse colony through routine monitoring, production of pseudopregnant females, breeding, tagging/biopsy, weaning, and animal transfer.

Genotype mouse tissues using PCR, sequencing, and other molecular biology techniques.

Assist in preparation and validation of genome editing reagents.

Cryopreserve mouse sperm and/or embryos and maintain the cryo‑storage database.

Coordinate import and export of frozen samples.

Produce mouse embryos via in‑vitro fertilization (IVF) for line recovery/importation or genome editing.

Assist in testing and implementation of new technologies.

Occasional weekend work will be required.

Perform other related duties as needed.

Ensure rigorous compliance with safety and regulatory requirements while performing assigned tasks.

Qualifications

Bachelor’s degree.

3 years related experience (or Master’s + 1 year experience in related field).

Job Details

Seniority level: Not Applicable

Employment type: Full‑time

Job function: Research

Industry: Hospitals and Health Care

Equal Opportunity Employer The Mount Sinai Health System is an equal opportunity employer, complying with all applicable federal civil rights laws. We do not discriminate, exclude, or treat individuals differently based on race, color, national origin, age, religion, disability, sex, sexual orientation, gender, veteran status, or any other characteristic protected by law. We are deeply committed to fostering an environment where all faculty, staff, students, trainees, patients, visitors, and the communities we serve feel respected and supported. Our goal is to create a healthcare and learning institution that actively works to remove barriers, address challenges, and promote fairness in all aspects of our organization.

Compensation The Mount Sinai Health System (MSHS) provides a salary range for this role of $58,824 - $88,236 annually. Actual salaries depend on a variety of factors, including experience, education, and operational need. The salary range does not include bonuses, incentive, differential pay, or other forms of compensation or benefits.

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