Novartis
Executive Clinical Program Leader - Translational Clinical Oncology
Novartis, Cambridge, Massachusetts, us, 02140
Executive Clinical Program Leader - Translational Clinical Oncology
This Executive Clinical Program Leader provides strategic, medical and scientific guidance and leadership for the development of multiple experimental agents in the Translational Clinical Oncology (TCO) portfolio, from early target identification through the Transition Decision Point. The role includes formulating actionable development plans, ensuring rapid decision-making and portfolio transitions, and informing external programs and business development initiatives.
Key Responsibilities
Serve as an Early Clinical Development Area Leader for TCO, overseeing innovative clinical strategies for multiple molecules/assets advancing in strategic indications.
Oversee physicians (including direct reports) with mentorship, ensuring program alignment with the overall oncology strategy and fostering career development.
Represent TCO programs and strategy at governance boards including the TCO-Leadership Team, Integrated Cancer Decision Board, Discovery & Translational Board, and cross‑organization boards.
Provide senior leadership and clinical input to clinical studies and pre‑clinical research projects, integrating medical knowledge with expertise across disciplines such as Clinical Pharmacology and Biostatistics.
Critically review and provide constructive feedback on study documents (protocols, Investigators’ Brochures, health authority responses).
Provide strategic input on internal and external assets and portfolio areas, leading TCO representation in Business Development and Licensing due diligence reviews.
Lead or help oversee external collaborations, partnering across the company.
Play leadership roles in early development committees and initiatives by contributing strategic advice to boards such as the Study Concept Review Board and Protocol Review Committee.
Mentor and serve as an educational resource and expert within the Biomedical Research organization and beyond.
Apply medical knowledge to guide the safe, ethical and efficient conduct of own trials, maintaining compliance with Good Clinical Practice guidelines and Novartis SOPs.
Coordinate with outside experts, investigators, and regulatory authorities in oncology early clinical development (FIH) trials.
Write and review abstracts and manuscripts for internal and external presentations and publications.
Essential Requirements
Position located at the Cambridge, MA site with no remote option; requires 20‑25% travel.
MD degree; PhD‑level basic science required (MD/PhD preferred). Board certification (or equivalent) in Hematology‑Oncology required.
7+ years of experience leading complex global early‑phase hematology‑oncology clinical programs from the pharma/biotech industry, plus credible academic medical center experience.
Recognized Heme‑Onc expert with a record of quality scientific publications and international recognition.
Strong interpretation skills for preclinical data (molecular biology, pharmacology, pharmacokinetics, toxicology).
Working knowledge of PK/PD and biostatistics for clinical development.
Proven ability to analyze and interpret oncology efficacy and safety data.
Knowledge of GCP and worldwide regulatory requirements for oncology trials.
Excellent scientific writing, oral communication, and presentation skills.
Proven ability to manage and develop a team.
Outstanding mentor who inspires others.
Strong personal ethical integrity and commitment to improving patient outcomes.
Salary : Expected range $261,100‑$484,900 per year. Final offer determined by experience and relevant skills; periodic review upon joining.
Benefits : Comprehensive health, life, disability, 401(k) with company match, generous paid time off, and additional benefits per employee handbook.
EEO Statement The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, sex, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status.
Accessibility & Reasonable Accommodations The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. To request accommodation, contact
recruiting@novartis.com
or call +1(877)395-2339 and provide the job requisition number.
#J-18808-Ljbffr
Key Responsibilities
Serve as an Early Clinical Development Area Leader for TCO, overseeing innovative clinical strategies for multiple molecules/assets advancing in strategic indications.
Oversee physicians (including direct reports) with mentorship, ensuring program alignment with the overall oncology strategy and fostering career development.
Represent TCO programs and strategy at governance boards including the TCO-Leadership Team, Integrated Cancer Decision Board, Discovery & Translational Board, and cross‑organization boards.
Provide senior leadership and clinical input to clinical studies and pre‑clinical research projects, integrating medical knowledge with expertise across disciplines such as Clinical Pharmacology and Biostatistics.
Critically review and provide constructive feedback on study documents (protocols, Investigators’ Brochures, health authority responses).
Provide strategic input on internal and external assets and portfolio areas, leading TCO representation in Business Development and Licensing due diligence reviews.
Lead or help oversee external collaborations, partnering across the company.
Play leadership roles in early development committees and initiatives by contributing strategic advice to boards such as the Study Concept Review Board and Protocol Review Committee.
Mentor and serve as an educational resource and expert within the Biomedical Research organization and beyond.
Apply medical knowledge to guide the safe, ethical and efficient conduct of own trials, maintaining compliance with Good Clinical Practice guidelines and Novartis SOPs.
Coordinate with outside experts, investigators, and regulatory authorities in oncology early clinical development (FIH) trials.
Write and review abstracts and manuscripts for internal and external presentations and publications.
Essential Requirements
Position located at the Cambridge, MA site with no remote option; requires 20‑25% travel.
MD degree; PhD‑level basic science required (MD/PhD preferred). Board certification (or equivalent) in Hematology‑Oncology required.
7+ years of experience leading complex global early‑phase hematology‑oncology clinical programs from the pharma/biotech industry, plus credible academic medical center experience.
Recognized Heme‑Onc expert with a record of quality scientific publications and international recognition.
Strong interpretation skills for preclinical data (molecular biology, pharmacology, pharmacokinetics, toxicology).
Working knowledge of PK/PD and biostatistics for clinical development.
Proven ability to analyze and interpret oncology efficacy and safety data.
Knowledge of GCP and worldwide regulatory requirements for oncology trials.
Excellent scientific writing, oral communication, and presentation skills.
Proven ability to manage and develop a team.
Outstanding mentor who inspires others.
Strong personal ethical integrity and commitment to improving patient outcomes.
Salary : Expected range $261,100‑$484,900 per year. Final offer determined by experience and relevant skills; periodic review upon joining.
Benefits : Comprehensive health, life, disability, 401(k) with company match, generous paid time off, and additional benefits per employee handbook.
EEO Statement The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, sex, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status.
Accessibility & Reasonable Accommodations The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. To request accommodation, contact
recruiting@novartis.com
or call +1(877)395-2339 and provide the job requisition number.
#J-18808-Ljbffr