Blueprint Medicines
Overview
How will your role help us transform hope into reality? Research, identify, and validate novel oncology targets and small molecule drug discovery, utilizing knowledge of bioengineering to develop and conduct cellular assays to support Blueprint Medicine’s novel drug discovery efforts. What will you do?
Manages and QC routines assays performed at CRO and upload data to our server. (15%) Optimize and employ cellular and molecular assays such as Western blotting, Elisa and immunofluorescence-based assays to elucidate mechanistic biology of potential drug targets and mechanism of action of small molecules. (20%) Present research findings at team meetings. (5%) Maintain our automation platform and is the point of contact with the vendor when needed (such as major issues to be fixed or implementation of new updates). (15%) Design and development of automation methods for biological assays for several projects. Teach colleagues how to use those methods and troubleshoot when necessary. (15%) Cell culture Maintenance. (10%) Run routine assays when needed. (10%) Maintain detailed and critical experimental data records that are published in ELN according to industry compliance. (10%) Minimum qualifications
Master’s degree in Bioengineering, Biomedical Engineering, or a closely related biological or life sciences field (or foreign equivalent degree), plus 1 year of experience in biological research for oncology drug development. Experience, which may be gained concurrently, must include: 1 year of experience in maintaining, expanding, and freezing cell lines. 1 year of experience with running routine assays such as Alphalisa pERK and proliferation assays. 1 year of experience in using and programming liquid handlers such as Bravo, Biomek, Integra Assist Plus and D300. 1 year of experience in analyzing cell research data and presenting it to the team. 1 year of experience in analyzing and presenting scientific research papers. 1 year of experience in maintaining detailed ELN to ensure data reproducibility. * This position is part of Blueprint Medicines’ employee referral program and is eligible for an employee referral incentive bonus. Why Blueprint?
At Blueprint Medicines, we achieve impactful results because of our global crew of compassionate innovators – the Blue Crew. Through authentic relationships and our collective entrepreneurial spirit and action, we are each empowered to take ownership and execute with strategic prioritization. We put trust in our people to break through norms and conventions using their individual strengths and insights, which drives our success. This is the place where the extraordinary becomes reality, and you could be part of it. Patients are waiting. Are you ready to make the leap? At Blueprint Medicines, we foster an environment of fair treatment and full participation for all of our employees as we navigate complex challenges in pursuing our mission to improve the lives of patients. We celebrate our unique differences and varied career and life experiences so that we can sustain our diverse culture and ensure everyone feels accepted. We are committed to non-discrimination, equal employment opportunity, as well as an inclusive recruitment process. We consider all qualified applicants based on merit and without regard to race, color, sex, gender identity, sexual orientation, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, or any other characteristic protected under applicable federal or state law. Blueprint Medicines, a Sanofi company, is a global biopharmaceutical company that invents life-changing medicines. We seek to improve and extend patients\' lives by solving important medical problems, with a focus on allergy/inflammation and oncology/hematology. Our approach begins by targeting the root causes of disease, using deep scientific knowledge in our core focus areas and drug discovery expertise across multiple therapeutic modalities. We have a track record of success with two approved medicines, including AYVAKIT/AYVAKYT (avapritinib) which we are bringing to patients with SM in the U.S. and Europe. Leveraging our established research, development, and commercial capability and infrastructure, we aim to significantly scale our impact by advancing a broad pipeline of programs ranging from early science to advanced clinical trials in mast cell diseases and solid tumors. For more information, visit
www.BlueprintMedicines.com
and follow us on X (formerly Twitter; @BlueprintMeds) and LinkedIn. Requisition #: 25-604 #LI-DNI We Invite You to Tell Us More About Yourself At Blueprint Medicines, we foster an environment of fair treatment and full participation to empower the Blue Crew to bring their authentic selves to work. We are committed to non-discrimination, equal employment opportunity, and an inclusive recruitment process, and we consider all applicants based on merit, without regard to any status protected under applicable law. We encourage you to share information about yourself by answering the questions below, to help us comply with federal government reporting and recordkeeping requirements on certain topics, and to help us measure the effectiveness of our efforts to ensure there are no unintended barriers to equal opportunity for all applicants in our recruitment and hiring processes. Please review the Government Ethnicity and Race Definitions when answering the questions below. Although all sections below require a response, you can always select "I don\'t wish to answer." Your responses will be kept confidential, will not be reviewed or used by anyone who makes hiring decisions, and will never be used against you. Thank you for sharing more about yourself and contributing to our efforts to ensure non-discrimination and equal opportunity for all. Voluntary Self-Identification of Protected Veteran Status Blueprint Medicines is a government contractor subject to the Vietnam Era Veterans\' Readjustment Assistance Act of 1974, as amended by the Jobs for Veterans Act of 2002, 38 U.S.C. 4212 (VEVRAA). As such, we take affirmative action to employ and advance in employment protected veterans, including by reaching out to veterans\' groups for qualified applicants and periodically reviewing our processes to ensure there are no unintended barriers. To help us measure the effectiveness of our outreach and recruitment efforts of veterans, we ask you to share if you are a veteran covered by VEVRAA. Answering is completely voluntary, but we hope you will do so, and your response will be used and kept confidential consistent with VEVRAA, and will not be used against you in any way. Please review these Protected Veteran Descriptions and check the appropriate box further below as to whether you belong to any of these government-defined categories. Voluntary Self-Identification of Disability Form CC-305 OMB Control Number 1250-0005 Why are you being asked to complete this form? We are a federal contractor or subcontractor. The law requires us to provide equal employment opportunity to qualified people with disabilities. We have a goal of having at least 7% of our workers as people with disabilities. The law says we must measure our progress towards this goal. To do this, we must ask applicants and employees if they have a disability or have ever had one. People can become disabled, so we need to ask this question at least every five years. Completing this form is voluntary, and we hope that you will choose to do so. Your answer is confidential. No one who makes hiring decisions will see it. If you want to learn more about the law or this form, visit the U.S. Department of Labor’s Office of Federal Contract Compliance Programs (OFCCP) website atwww.dol.gov/ofccp . How do you know if you have a disability? A disability is a condition that substantially limits one or more of your “major life activities.” If you have or have ever had such a condition, you are a person with a disability.
Disabilities include, but are not limited to: Alcohol or other substance use disorder (not currently using drugs illegally) Blind or low vision Cancer (past or present) Cardiovascular or heart disease Celiac disease Cerebral palsy Deaf or serious difficulty hearing Diabetes Disfigurement, for example, disfigurement caused by burns, wounds, accidents, or congenital disorders Epilepsy or other seizure disorder Gastrointestinal disorders, for example, Crohn's Disease, irritable bowel syndrome Mental health conditions, for example, depression, bipolar disorder, anxiety disorder, schizophrenia, PTSD Missing limbs or partially missing limbs Mobility impairment, benefiting from the use of a wheelchair, scooter, walker, leg brace(s) and/or other supports Nervous system condition, for example, migraine headaches, Parkinson’s disease, multiple sclerosis (MS) Neurodivergence, for example, attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder, dyslexia, dyspraxia, other learning disabilities Partial or complete paralysis (any cause) Pulmonary or respiratory conditions, for example, tuberculosis, asthma, emphysema PUBLIC BURDEN STATEMENT: According to the Paperwork Reduction Act of 1995 no persons are required to respond to a collection of information unless such collection displays a valid OMB control number. This survey should take about 5 minutes to complete. Please check one of the boxes below: Please check one of these boxes: * Select... Please identify your protected veteran status: * Select... Are you of Hispanic or Latino ethnicity? * Select... Please select the race(s) you identify with: * Select... Please identify your gender (Select all that apply): * Select... Please identify your sexual orientation: * Select... By checking this box, I consent to Blueprint Medicines, a Sanofi company collecting, storing, and processing my responses to the demographic data surveys above. *
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How will your role help us transform hope into reality? Research, identify, and validate novel oncology targets and small molecule drug discovery, utilizing knowledge of bioengineering to develop and conduct cellular assays to support Blueprint Medicine’s novel drug discovery efforts. What will you do?
Manages and QC routines assays performed at CRO and upload data to our server. (15%) Optimize and employ cellular and molecular assays such as Western blotting, Elisa and immunofluorescence-based assays to elucidate mechanistic biology of potential drug targets and mechanism of action of small molecules. (20%) Present research findings at team meetings. (5%) Maintain our automation platform and is the point of contact with the vendor when needed (such as major issues to be fixed or implementation of new updates). (15%) Design and development of automation methods for biological assays for several projects. Teach colleagues how to use those methods and troubleshoot when necessary. (15%) Cell culture Maintenance. (10%) Run routine assays when needed. (10%) Maintain detailed and critical experimental data records that are published in ELN according to industry compliance. (10%) Minimum qualifications
Master’s degree in Bioengineering, Biomedical Engineering, or a closely related biological or life sciences field (or foreign equivalent degree), plus 1 year of experience in biological research for oncology drug development. Experience, which may be gained concurrently, must include: 1 year of experience in maintaining, expanding, and freezing cell lines. 1 year of experience with running routine assays such as Alphalisa pERK and proliferation assays. 1 year of experience in using and programming liquid handlers such as Bravo, Biomek, Integra Assist Plus and D300. 1 year of experience in analyzing cell research data and presenting it to the team. 1 year of experience in analyzing and presenting scientific research papers. 1 year of experience in maintaining detailed ELN to ensure data reproducibility. * This position is part of Blueprint Medicines’ employee referral program and is eligible for an employee referral incentive bonus. Why Blueprint?
At Blueprint Medicines, we achieve impactful results because of our global crew of compassionate innovators – the Blue Crew. Through authentic relationships and our collective entrepreneurial spirit and action, we are each empowered to take ownership and execute with strategic prioritization. We put trust in our people to break through norms and conventions using their individual strengths and insights, which drives our success. This is the place where the extraordinary becomes reality, and you could be part of it. Patients are waiting. Are you ready to make the leap? At Blueprint Medicines, we foster an environment of fair treatment and full participation for all of our employees as we navigate complex challenges in pursuing our mission to improve the lives of patients. We celebrate our unique differences and varied career and life experiences so that we can sustain our diverse culture and ensure everyone feels accepted. We are committed to non-discrimination, equal employment opportunity, as well as an inclusive recruitment process. We consider all qualified applicants based on merit and without regard to race, color, sex, gender identity, sexual orientation, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, or any other characteristic protected under applicable federal or state law. Blueprint Medicines, a Sanofi company, is a global biopharmaceutical company that invents life-changing medicines. We seek to improve and extend patients\' lives by solving important medical problems, with a focus on allergy/inflammation and oncology/hematology. Our approach begins by targeting the root causes of disease, using deep scientific knowledge in our core focus areas and drug discovery expertise across multiple therapeutic modalities. We have a track record of success with two approved medicines, including AYVAKIT/AYVAKYT (avapritinib) which we are bringing to patients with SM in the U.S. and Europe. Leveraging our established research, development, and commercial capability and infrastructure, we aim to significantly scale our impact by advancing a broad pipeline of programs ranging from early science to advanced clinical trials in mast cell diseases and solid tumors. For more information, visit
www.BlueprintMedicines.com
and follow us on X (formerly Twitter; @BlueprintMeds) and LinkedIn. Requisition #: 25-604 #LI-DNI We Invite You to Tell Us More About Yourself At Blueprint Medicines, we foster an environment of fair treatment and full participation to empower the Blue Crew to bring their authentic selves to work. We are committed to non-discrimination, equal employment opportunity, and an inclusive recruitment process, and we consider all applicants based on merit, without regard to any status protected under applicable law. We encourage you to share information about yourself by answering the questions below, to help us comply with federal government reporting and recordkeeping requirements on certain topics, and to help us measure the effectiveness of our efforts to ensure there are no unintended barriers to equal opportunity for all applicants in our recruitment and hiring processes. Please review the Government Ethnicity and Race Definitions when answering the questions below. Although all sections below require a response, you can always select "I don\'t wish to answer." Your responses will be kept confidential, will not be reviewed or used by anyone who makes hiring decisions, and will never be used against you. Thank you for sharing more about yourself and contributing to our efforts to ensure non-discrimination and equal opportunity for all. Voluntary Self-Identification of Protected Veteran Status Blueprint Medicines is a government contractor subject to the Vietnam Era Veterans\' Readjustment Assistance Act of 1974, as amended by the Jobs for Veterans Act of 2002, 38 U.S.C. 4212 (VEVRAA). As such, we take affirmative action to employ and advance in employment protected veterans, including by reaching out to veterans\' groups for qualified applicants and periodically reviewing our processes to ensure there are no unintended barriers. To help us measure the effectiveness of our outreach and recruitment efforts of veterans, we ask you to share if you are a veteran covered by VEVRAA. Answering is completely voluntary, but we hope you will do so, and your response will be used and kept confidential consistent with VEVRAA, and will not be used against you in any way. Please review these Protected Veteran Descriptions and check the appropriate box further below as to whether you belong to any of these government-defined categories. Voluntary Self-Identification of Disability Form CC-305 OMB Control Number 1250-0005 Why are you being asked to complete this form? We are a federal contractor or subcontractor. The law requires us to provide equal employment opportunity to qualified people with disabilities. We have a goal of having at least 7% of our workers as people with disabilities. The law says we must measure our progress towards this goal. To do this, we must ask applicants and employees if they have a disability or have ever had one. People can become disabled, so we need to ask this question at least every five years. Completing this form is voluntary, and we hope that you will choose to do so. Your answer is confidential. No one who makes hiring decisions will see it. If you want to learn more about the law or this form, visit the U.S. Department of Labor’s Office of Federal Contract Compliance Programs (OFCCP) website atwww.dol.gov/ofccp . How do you know if you have a disability? A disability is a condition that substantially limits one or more of your “major life activities.” If you have or have ever had such a condition, you are a person with a disability.
Disabilities include, but are not limited to: Alcohol or other substance use disorder (not currently using drugs illegally) Blind or low vision Cancer (past or present) Cardiovascular or heart disease Celiac disease Cerebral palsy Deaf or serious difficulty hearing Diabetes Disfigurement, for example, disfigurement caused by burns, wounds, accidents, or congenital disorders Epilepsy or other seizure disorder Gastrointestinal disorders, for example, Crohn's Disease, irritable bowel syndrome Mental health conditions, for example, depression, bipolar disorder, anxiety disorder, schizophrenia, PTSD Missing limbs or partially missing limbs Mobility impairment, benefiting from the use of a wheelchair, scooter, walker, leg brace(s) and/or other supports Nervous system condition, for example, migraine headaches, Parkinson’s disease, multiple sclerosis (MS) Neurodivergence, for example, attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder, dyslexia, dyspraxia, other learning disabilities Partial or complete paralysis (any cause) Pulmonary or respiratory conditions, for example, tuberculosis, asthma, emphysema PUBLIC BURDEN STATEMENT: According to the Paperwork Reduction Act of 1995 no persons are required to respond to a collection of information unless such collection displays a valid OMB control number. This survey should take about 5 minutes to complete. Please check one of the boxes below: Please check one of these boxes: * Select... Please identify your protected veteran status: * Select... Are you of Hispanic or Latino ethnicity? * Select... Please select the race(s) you identify with: * Select... Please identify your gender (Select all that apply): * Select... Please identify your sexual orientation: * Select... By checking this box, I consent to Blueprint Medicines, a Sanofi company collecting, storing, and processing my responses to the demographic data surveys above. *
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