Postdoctoral Position in Polycystic Kidney Disease Research at Qian Lab

Job Description Job title: Postdoctoral Position in Polycystic Kidney Disease Research - Qian Lab Job description: Applicants are sought for a two-year, potentially extendable, full-time postdoctoral position in the laboratory of Dr. Feng Qian, investigating molecular mechanisms underlying polycystic kidney disease (PKD). PKD is the most common genetic cause of renal failure, caused by mutations in the PKD1, PKD2, or PKHD1 genes, which encode polycystin-1, -2, or fibrocystin/polyductin, respectively. The laboratory is located in the state-of-the-art Health Sciences Facility III Building on the campus and is part of the Baltimore PKD Research Center supported by NIH R01 grants and the U54 PKD Research Consortium ( https://www.pkd-rrc.org/about-pkd-rrc/ ). The postdoctoral researcher will join a group studying PKD using biochemical, biophysical, cell biological, systems biology methods, and mouse models. The primary focus will be on a project investigating the role of polycystin complexes as ion channels and their function in primary cilia in kidney physiology and disease. The project will also explore the regulation of polycystin-1 via cleavage at the G-protein coupled receptor proteolysis site (GPS) motif, a key posttranslational modification involved in cell signaling. The laboratory fosters a highly collaborative environment with opportunities to contribute to related ciliopathy projects. Qualifications

Qualifications and experience: Requirements include a Ph.D. (or equivalent) in cellular and molecular biology or related disciplines. Desirable skills include experience with mouse experimentation, histology, microscopy, cell culture, biochemistry, cell signaling, and molecular biology techniques. UMB is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected Veteran status, age, or any other characteristic protected by law or policy. For assistance related to employment, contact the Staffing department at

HRJobs@umaryland.edu . If you anticipate needing a reasonable accommodation for a disability under the Americans with Disabilities Act (ADA) during any part of the employment process, please submit a

UMB Job Applicant Accommodation Request . You may also contact

HRDiversity@umaryland.edu . Please note that inquiries concerning ADA accommodations will only be responded to from this email address.

#J-18808-Ljbffr