University of California, Los Angeles
Assistant Project Scientist in Virology - Mehdi Bouhaddou Lab
University of California, Los Angeles, Los Angeles, California, United States, 90079
Assistant Project Scientist in Virology - Mehdi Bouhaddou Lab
University of California Los Angeles
Requisition Number:
JPF09196
Assistant Project Scientist in Virology
UCLA's Department of Microbiology, Immunology and Molecular Genetics is seeking to fill a full-time Assistant Project Scientist position in the Mehdi Bouhaddou Lab. The incumbent will study post-translational modifications at the virus-host using a combination of experimental virology, mass spectrometry proteomics, and bioinformatics. About the Lab
The Bouhaddou lab ( https://www.bouhaddoulab.org/
and
https://www.mimg.ucla.edu/people/mehdi-bouhaddou-ph-d/ ) is a Quantitative Systems Biology lab that opened in February 2023 as part of the Department of Microbiology, Immunology, and Molecular Genetics (MIMG) ( https://www.mimg.ucla.edu/ ) and Quantitative and Computational Biosciences Institute (QCBio) ( https://qcb.ucla.edu/ ) at the University of California Los Angeles (UCLA). Dr. Bouhaddou performed his PhD in mathematical modeling with Marc Birtwistle and postdoc in virology and proteomics with Nevan Krogan (for a list of prior publications:
https://scholar.google.com/citations?user=2_U6F9EAAAAJ&hl=en ). The Bouhaddou lab believes in diversity, equity, and inclusion and is committed to strong mentorship of trainees to help them reach their career goals.
The lab is generally focused on studying virus-host interactions using mass spectrometry proteomics, bioinformatics, and molecular biology to systematically compare how different viruses manipulate, and are manipulated by, host-generated post-translational modifications. Candidates need no prior experience in mass spectrometry proteomics or computer programming, only prior experience in molecular virology and molecular biology is required; the other disciplines can be learned. The lab is open to studying a range of viruses and host systems, interested to: Map host post-translational modification cascades manipulated by different viruses. Identify mechanisms by which viruses manipulate signaling cascades. Understand the impact of viral protein post-translational modifications. Identify host enzyme dependencies to identify multi-virus therapeutic targets.
The Bouhaddou lab possesses a mass spectrometry instrument as well as adjoining wet and dry lab space, available to lab members for training and research.
Specific responsibilities for this position include but are not limited to: Conduct research on how different viruses perturb the host and viral phosphorylation landscape during infection using mass spectrometry phosphoproteomics. Carry out both molecular biology techniques, including cloning, quantitative PCR, and western blotting. Perform mammalian cell culture in a BSL-2 environment. Perform virology experiments in a BSL-3 environment. Mentor graduate students and other members of the lab to perform molecular virology techniques. Assist with preparation of grant proposals. Prepare manuscripts for publication in scientific journals.
Minimum Qualifications: Ph.D. or M.D. degree (or equivalent)
Prior expertise in molecular virology and molecular biology
Interested candidates should apply online at
https://recruit.apo.ucla.edu/JPF09196 .
Cultural North Star The shared values of the DGSOM are expressed in the Cultural North Star, which was developed by members of our community and affirms our unswerving commitment to doing what's right, making things better, and being kind. These are the standards to which we hold ourselves, and one another. Please read more about this important DGSOM program at
https://medschool.ucla.edu/cultural-north-star .
Anti-Racism Roadmap The David Geffen School of Medicine Anti-racism roadmap is our co-created path to ensuring racial justice, equity, diversity and inclusion. We are committed to actively dismantling structural racism in our organization as described in more detail at:
https://medschool.ucla.edu/diversity-anti-racism-roadmap .
To apply, please visit:
https://recruit.apo.ucla.edu/JPF09196
The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status. For the complete University of California nondiscrimination and affirmative action policy, see: UC Nondiscrimination & Affirmative Action Policy,
https://policy.ucop.edu/doc/4000376/DiscHarassAffirmAction jeid-f488b0fb37287b4aae0c80ad5b63c09b
#J-18808-Ljbffr
Requisition Number:
JPF09196
Assistant Project Scientist in Virology
UCLA's Department of Microbiology, Immunology and Molecular Genetics is seeking to fill a full-time Assistant Project Scientist position in the Mehdi Bouhaddou Lab. The incumbent will study post-translational modifications at the virus-host using a combination of experimental virology, mass spectrometry proteomics, and bioinformatics. About the Lab
The Bouhaddou lab ( https://www.bouhaddoulab.org/
and
https://www.mimg.ucla.edu/people/mehdi-bouhaddou-ph-d/ ) is a Quantitative Systems Biology lab that opened in February 2023 as part of the Department of Microbiology, Immunology, and Molecular Genetics (MIMG) ( https://www.mimg.ucla.edu/ ) and Quantitative and Computational Biosciences Institute (QCBio) ( https://qcb.ucla.edu/ ) at the University of California Los Angeles (UCLA). Dr. Bouhaddou performed his PhD in mathematical modeling with Marc Birtwistle and postdoc in virology and proteomics with Nevan Krogan (for a list of prior publications:
https://scholar.google.com/citations?user=2_U6F9EAAAAJ&hl=en ). The Bouhaddou lab believes in diversity, equity, and inclusion and is committed to strong mentorship of trainees to help them reach their career goals.
The lab is generally focused on studying virus-host interactions using mass spectrometry proteomics, bioinformatics, and molecular biology to systematically compare how different viruses manipulate, and are manipulated by, host-generated post-translational modifications. Candidates need no prior experience in mass spectrometry proteomics or computer programming, only prior experience in molecular virology and molecular biology is required; the other disciplines can be learned. The lab is open to studying a range of viruses and host systems, interested to: Map host post-translational modification cascades manipulated by different viruses. Identify mechanisms by which viruses manipulate signaling cascades. Understand the impact of viral protein post-translational modifications. Identify host enzyme dependencies to identify multi-virus therapeutic targets.
The Bouhaddou lab possesses a mass spectrometry instrument as well as adjoining wet and dry lab space, available to lab members for training and research.
Specific responsibilities for this position include but are not limited to: Conduct research on how different viruses perturb the host and viral phosphorylation landscape during infection using mass spectrometry phosphoproteomics. Carry out both molecular biology techniques, including cloning, quantitative PCR, and western blotting. Perform mammalian cell culture in a BSL-2 environment. Perform virology experiments in a BSL-3 environment. Mentor graduate students and other members of the lab to perform molecular virology techniques. Assist with preparation of grant proposals. Prepare manuscripts for publication in scientific journals.
Minimum Qualifications: Ph.D. or M.D. degree (or equivalent)
Prior expertise in molecular virology and molecular biology
Interested candidates should apply online at
https://recruit.apo.ucla.edu/JPF09196 .
Cultural North Star The shared values of the DGSOM are expressed in the Cultural North Star, which was developed by members of our community and affirms our unswerving commitment to doing what's right, making things better, and being kind. These are the standards to which we hold ourselves, and one another. Please read more about this important DGSOM program at
https://medschool.ucla.edu/cultural-north-star .
Anti-Racism Roadmap The David Geffen School of Medicine Anti-racism roadmap is our co-created path to ensuring racial justice, equity, diversity and inclusion. We are committed to actively dismantling structural racism in our organization as described in more detail at:
https://medschool.ucla.edu/diversity-anti-racism-roadmap .
To apply, please visit:
https://recruit.apo.ucla.edu/JPF09196
The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status. For the complete University of California nondiscrimination and affirmative action policy, see: UC Nondiscrimination & Affirmative Action Policy,
https://policy.ucop.edu/doc/4000376/DiscHarassAffirmAction jeid-f488b0fb37287b4aae0c80ad5b63c09b
#J-18808-Ljbffr