Howard Hughes Medical Institute (HHMI)
Research Technician - Brown Lab
Howard Hughes Medical Institute (HHMI), New York, New York, us, 10261
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Research Technician - Brown Lab
role at
Howard Hughes Medical Institute (HHMI) . About the Role The Brown Laboratory (www.thebrownlaboratory.com) is seeking a highly motivated and detail-oriented
Research Technician
to support our cutting-edge research in immune regulation. The lab investigates mechanisms of immune tolerance across host–microbiota interactions, autoimmunity, cancer, and early-life immune development. Recent work from the lab has defined the cell types and mechanisms that instruct peripheral regulatory T cell development and tolerance to the gut microbiota. Led by physician–scientist
Dr. Chrysothemis Brown , the lab bridges mechanistic studies in experimental models with translational human immunology, collaborating closely with Memorial Sloan Kettering Cancer Center (MSK) and the Hospital for Special Surgery. The Brown Lab is located in the Zuckerman Research Center on the Tri-Institutional campus (MSK, Weill Cornell, and Rockefeller University) in New York City’s Upper East Side. This position is ideal for candidates who are interested in working 2 years prior to pursuing graduate or medical school, offering a unique opportunity to gain hands-on experience and mentorship in a leading immunology lab. Application Instructions Please include—preferably as a single PDF: Cover letter describing your research interests and goals CV (including relevant technical skills and any publications) Names and contact information for at least two references What You’ll Get Comprehensive Training in advanced techniques, including in vivo mouse handling, tissue processing, and high-dimensional flow cytometry Close mentorship from senior lab members, with opportunities for skill development and project ownership Preparation for Graduate or Medical School, including career guidance and research experience in a world-class biomedical environment Publications and Authorship Opportunities, including potential for co-first author contributions Exposure to Translational Research through collaborations with clinical teams at MSK and HSS Collaborative, supportive environment that values teamwork, communication, and scientific curiosity What You Will Do Conduct experiments using in vivo mouse models, including animal handling, dissections, and tissue processing Manage mouse colonies, including breeding and genotyping Perform immune phenotyping via high-dimensional flow cytometry Prepare samples for single-cell genomics workflows (scRNA-seq / scATAC-seq) Carry out molecular biology and microbiology experiments (e.g., bacterial cultures, genome editing) Maintain accurate records and protocols using an electronic lab notebook Collaborate closely with team members, contribute to lab meetings, and assist in training new members What You Bring Bachelor’s degree in Biological Sciences, Biochemistry, Immunology, Microbiology, Molecular Biology, Genetics, or a related field Required: Experience with animal handling and mouse colony management Highly Preferred: Hands-on experience with flow cytometry and animal dissection / tissue processing Strong organizational and time management skills with the ability to thrive in a fast-paced lab environment Excellent communication skills and a team-oriented mindset — enjoys collaborating and contributing to shared goals Genuine enthusiasm for science, curiosity, and a desire to learn new techniques Physical Requirements Remaining in a normal seated or standing position for extended periods of time; reaching and grasping by extending hand(s) or arm(s); dexterity to manipulate objects with fingers; ability to see and hear within normal parameters; ability to move about the workspace. The position requires mobility, including the ability to move materials weighing up to several pounds. Work may involve exposure to malodorous vapors, low-dose radiation, contamination by toxic chemicals and acids, and presence of hazardous materials. Reasonable accommodations will be evaluated on an individual basis. Please Note This job description sets forth the job’s principal duties, responsibilities, and requirements; it should not be construed as an exhaustive statement. Essential duties and responsibilities described herein are considered “essential functions” of the job, as defined by the Americans with Disabilities Act unless they begin with the word “may.” Compensation And Benefits Our employees are compensated from a total rewards perspective in many ways for their contributions to our mission, including competitive pay, exceptional health benefits, retirement plans, time off, and a range of recognition and wellness programs. Visit our Benefits at HHMI site to learn more. Compensation Range $19.24 (minimum) - $24.09 (midpoint) - $31.29 (maximum) Pay Type: Hourly HHMI’s salary structure is developed based on relevant job market data. HHMI considers a candidate’s education, previous experiences, knowledge, skills and abilities, as well as internal consistency when making job offers. HHMI is an Equal Opportunity Employer. We use E-Verify to confirm the identity and employment eligibility of all new hires.
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Research Technician - Brown Lab
role at
Howard Hughes Medical Institute (HHMI) . About the Role The Brown Laboratory (www.thebrownlaboratory.com) is seeking a highly motivated and detail-oriented
Research Technician
to support our cutting-edge research in immune regulation. The lab investigates mechanisms of immune tolerance across host–microbiota interactions, autoimmunity, cancer, and early-life immune development. Recent work from the lab has defined the cell types and mechanisms that instruct peripheral regulatory T cell development and tolerance to the gut microbiota. Led by physician–scientist
Dr. Chrysothemis Brown , the lab bridges mechanistic studies in experimental models with translational human immunology, collaborating closely with Memorial Sloan Kettering Cancer Center (MSK) and the Hospital for Special Surgery. The Brown Lab is located in the Zuckerman Research Center on the Tri-Institutional campus (MSK, Weill Cornell, and Rockefeller University) in New York City’s Upper East Side. This position is ideal for candidates who are interested in working 2 years prior to pursuing graduate or medical school, offering a unique opportunity to gain hands-on experience and mentorship in a leading immunology lab. Application Instructions Please include—preferably as a single PDF: Cover letter describing your research interests and goals CV (including relevant technical skills and any publications) Names and contact information for at least two references What You’ll Get Comprehensive Training in advanced techniques, including in vivo mouse handling, tissue processing, and high-dimensional flow cytometry Close mentorship from senior lab members, with opportunities for skill development and project ownership Preparation for Graduate or Medical School, including career guidance and research experience in a world-class biomedical environment Publications and Authorship Opportunities, including potential for co-first author contributions Exposure to Translational Research through collaborations with clinical teams at MSK and HSS Collaborative, supportive environment that values teamwork, communication, and scientific curiosity What You Will Do Conduct experiments using in vivo mouse models, including animal handling, dissections, and tissue processing Manage mouse colonies, including breeding and genotyping Perform immune phenotyping via high-dimensional flow cytometry Prepare samples for single-cell genomics workflows (scRNA-seq / scATAC-seq) Carry out molecular biology and microbiology experiments (e.g., bacterial cultures, genome editing) Maintain accurate records and protocols using an electronic lab notebook Collaborate closely with team members, contribute to lab meetings, and assist in training new members What You Bring Bachelor’s degree in Biological Sciences, Biochemistry, Immunology, Microbiology, Molecular Biology, Genetics, or a related field Required: Experience with animal handling and mouse colony management Highly Preferred: Hands-on experience with flow cytometry and animal dissection / tissue processing Strong organizational and time management skills with the ability to thrive in a fast-paced lab environment Excellent communication skills and a team-oriented mindset — enjoys collaborating and contributing to shared goals Genuine enthusiasm for science, curiosity, and a desire to learn new techniques Physical Requirements Remaining in a normal seated or standing position for extended periods of time; reaching and grasping by extending hand(s) or arm(s); dexterity to manipulate objects with fingers; ability to see and hear within normal parameters; ability to move about the workspace. The position requires mobility, including the ability to move materials weighing up to several pounds. Work may involve exposure to malodorous vapors, low-dose radiation, contamination by toxic chemicals and acids, and presence of hazardous materials. Reasonable accommodations will be evaluated on an individual basis. Please Note This job description sets forth the job’s principal duties, responsibilities, and requirements; it should not be construed as an exhaustive statement. Essential duties and responsibilities described herein are considered “essential functions” of the job, as defined by the Americans with Disabilities Act unless they begin with the word “may.” Compensation And Benefits Our employees are compensated from a total rewards perspective in many ways for their contributions to our mission, including competitive pay, exceptional health benefits, retirement plans, time off, and a range of recognition and wellness programs. Visit our Benefits at HHMI site to learn more. Compensation Range $19.24 (minimum) - $24.09 (midpoint) - $31.29 (maximum) Pay Type: Hourly HHMI’s salary structure is developed based on relevant job market data. HHMI considers a candidate’s education, previous experiences, knowledge, skills and abilities, as well as internal consistency when making job offers. HHMI is an Equal Opportunity Employer. We use E-Verify to confirm the identity and employment eligibility of all new hires.
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