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Lumicity

Senior Medical Director (, MA, United States)

Lumicity, , MA, United States

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This range is provided by Lumicity. Your actual pay will be based on your skills and experience talk with your recruiter to learn more.

Base pay range

$220,000.00/yr - $260,000.00/yr

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Recruitment Consultant | Biotech, Biopharma and Pharmaceutical | United States

Salary: $220,000-$260,000 annually

Job Title: Senior Medical Director Cardiovascular Medicine & Clinical Development

Location: Massachusetts (On-Site)

Job Description:

An emerging biotechnology company is seeking a Senior Medical Director to lead the clinical development strategy and execution for a first-in-class therapeutic candidate targeting Hypertrophic Cardiomyopathy (HCM) . This pivotal leadership role offers the opportunity to shape and drive innovative approaches in cardiovascular medicine within a dynamic, science-driven environment.

You will play a central role in the companys mission to develop transformative RNA-based therapies . Responsibilities include overseeing early-phase clinical trials, integrating precision medicine into trial designs, and ensuring rigorous medical and regulatory oversight. You will collaborate across preclinical, clinical, regulatory, and commercial functions to ensure clinical strategy is aligned with company goals.

Key Responsibilities:

Therapeutic Area Leadership:

  • Lead clinical strategy and execution for a pipeline asset in HCM and related cardiomyopathies.
  • Guide the development of precision therapeutics by incorporating insights from translational science and biomarker research.
  • Collaborate with internal and external experts to advance the program from early development to pivotal trials.
  • Ensure the program reflects the latest advances in cardiovascular biology and therapeutic innovation.

Clinical Development & Medical Oversight:

  • Design and oversee early-phase clinical trials, including first-in-human studies.
  • Serve as medical lead and monitor across key studies.
  • Collaborate with biomarker, imaging, and genomics teams to optimize patient selection and trial endpoints.
  • Ensure regulatory and ethical standards are met for global submissions.

Cross-Functional Collaboration:

  • Work closely with cross-functional teams including research, clinical operations, regulatory, and executive leadership.
  • Engage with external stakeholders including KOLs, advisory boards, and safety monitoring boards.
  • Stay abreast of emerging scientific literature in HCM and RNA-based or genetic medicine.

Regulatory & Strategic Support:

  • Contribute to the preparation and review of regulatory submissions and clinical trial applications (IND/CTA).
  • Ensure alignment with global regulatory standards and agencies (FDA, EMA, etc.).

Qualifications:

  • MD or MD/PhD with a focus in cardiology or a related discipline.
  • 10+ years in cardiovascular clinical development, including significant experience in HCM or genetic cardiomyopathies.
  • Experience leading clinical programs through early development stages.
  • Board Certification in Cardiology or a related field is highly desirable.
  • Experience in RNA therapeutics, genetic medicine, or rare diseases is a plus but not required.

If interested, please apply below or send CV to

Seniority level

  • Seniority level

    Director

Employment type

  • Employment type

    Full-time

Job function

  • Job function

    Science

  • Industries

    Pharmaceutical Manufacturing

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