Lyterian Therapeutics
Principal Scientist, Medicinal Chemistry
Lyterian Therapeutics, San Francisco, California, United States, 94199
Principal Scientist, Medicinal Chemistry
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Principal Scientist, Medicinal Chemistry
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Lyterian Therapeutics Principal Scientist, Medicinal Chemistry
Join to apply for the
Principal Scientist, Medicinal Chemistry
role at
Lyterian Therapeutics Lyterian Therapeutics provided pay range
This range is provided by Lyterian Therapeutics. Your actual pay will be based on your skills and experience — talk with your recruiter to learn more. Base pay range
$155,000.00/yr - $185,000.00/yr At Lyterian Therapeutics, we are committed to developing medicines for patients in need by co-opting physiologically-relevant protein homeostatic mechanisms to regulate genetically-validated targets.
As Principal Scientist, Medicinal Chemistry, you will leverage your extensive experience in and passion for the discovery and optimization of small molecule therapeutics to advance Lyterian’s internal pipeline toward the clinic. You will work closely with the senior management team and be directly responsible for leading and growing Lyterian’s internal and external teams of chemists.
We look for teammates who are inspired by our mission and want to work in a collaborative, rigorous, and entrepreneurial environment. We seek candidates who are self-motivated, collaborative, proactive, and possess a strong desire to discover novel biology and new drugs. Efficient time management, excellent organizational and communication skills, and passion for high-quality, translational science are essential.
Impact You'll Make:
Design and develop small molecule compounds, libraries, and probes based on rigorous data analysis and sound hypotheses Collaborate and supervise the synthesis of designed small molecules, libraries, and probes at CROs Develop and contribute to company's intellectual property (IP) domain by way of patents and/or publications Stay up-to-date with emerging scientific literature Collaborate and communicate across a diverse scientific team to successfully progress Lyterian goals
Qualifications:
PhD in chemistry with 7-10 years relevant industry experience, at least 3 years in a Drug Discovery setting Expertise in small molecule chemistry (structure-based and/or pharmacophore-based drug design, synthetic organic chemistry, ADME/DMPK optimization) Record of accomplishment in one or more of the following areas: medicinal chemistry, methodology/catalysis, total synthesis, and optionally chemical biology and physical organic chemistry Track record of advancing small molecule medicinal chemistry programs leading to clinical candidates is preferred Experience with compound scale-up and is a plus Understanding and utilization of computer-aided drug design (CADD) Initiative and boldness to dive into a fast-paced new startup
At Lyterian, we believe that a diverse, open, and inclusive environment and culture is key to our success. We will not be influenced in recruiting, hiring, promoting or any other employment practices by race, color, citizenship status, national origin, ancestry, sex, sexual orientation, gender identity/expression, age, religion, physical or mental disability, medical or genetic condition, marital status, veteran status, or any other characteristics protected under applicable federal, state and local laws. Lyterian will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable laws.
Note to External Recruiters: Submission of unsolicited resumes prior to an agreement set in place does not create any implied obligation.
The expected base salary range for this role is $155,000 - $185,000. We encourage candidates of all levels to apply as there is often flexibility on job title and responsibilities. Compensation will be based on a variety of factors, including experience, qualifications, internal equity and location. Lyterian offers a competitive employment package that includes an annual bonus, significant equity, and a generous benefits package including comprehensive health, dental, and vision insurance for our employees and their families, plus a 401K match. Seniority level
Seniority level Not Applicable Employment type
Employment type Full-time Job function
Job function Research, Analyst, and Information Technology Referrals increase your chances of interviewing at Lyterian Therapeutics by 2x Get notified about new Chemist jobs in
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Join to apply for the
Principal Scientist, Medicinal Chemistry
role at
Lyterian Therapeutics Principal Scientist, Medicinal Chemistry
Join to apply for the
Principal Scientist, Medicinal Chemistry
role at
Lyterian Therapeutics Lyterian Therapeutics provided pay range
This range is provided by Lyterian Therapeutics. Your actual pay will be based on your skills and experience — talk with your recruiter to learn more. Base pay range
$155,000.00/yr - $185,000.00/yr At Lyterian Therapeutics, we are committed to developing medicines for patients in need by co-opting physiologically-relevant protein homeostatic mechanisms to regulate genetically-validated targets.
As Principal Scientist, Medicinal Chemistry, you will leverage your extensive experience in and passion for the discovery and optimization of small molecule therapeutics to advance Lyterian’s internal pipeline toward the clinic. You will work closely with the senior management team and be directly responsible for leading and growing Lyterian’s internal and external teams of chemists.
We look for teammates who are inspired by our mission and want to work in a collaborative, rigorous, and entrepreneurial environment. We seek candidates who are self-motivated, collaborative, proactive, and possess a strong desire to discover novel biology and new drugs. Efficient time management, excellent organizational and communication skills, and passion for high-quality, translational science are essential.
Impact You'll Make:
Design and develop small molecule compounds, libraries, and probes based on rigorous data analysis and sound hypotheses Collaborate and supervise the synthesis of designed small molecules, libraries, and probes at CROs Develop and contribute to company's intellectual property (IP) domain by way of patents and/or publications Stay up-to-date with emerging scientific literature Collaborate and communicate across a diverse scientific team to successfully progress Lyterian goals
Qualifications:
PhD in chemistry with 7-10 years relevant industry experience, at least 3 years in a Drug Discovery setting Expertise in small molecule chemistry (structure-based and/or pharmacophore-based drug design, synthetic organic chemistry, ADME/DMPK optimization) Record of accomplishment in one or more of the following areas: medicinal chemistry, methodology/catalysis, total synthesis, and optionally chemical biology and physical organic chemistry Track record of advancing small molecule medicinal chemistry programs leading to clinical candidates is preferred Experience with compound scale-up and is a plus Understanding and utilization of computer-aided drug design (CADD) Initiative and boldness to dive into a fast-paced new startup
At Lyterian, we believe that a diverse, open, and inclusive environment and culture is key to our success. We will not be influenced in recruiting, hiring, promoting or any other employment practices by race, color, citizenship status, national origin, ancestry, sex, sexual orientation, gender identity/expression, age, religion, physical or mental disability, medical or genetic condition, marital status, veteran status, or any other characteristics protected under applicable federal, state and local laws. Lyterian will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable laws.
Note to External Recruiters: Submission of unsolicited resumes prior to an agreement set in place does not create any implied obligation.
The expected base salary range for this role is $155,000 - $185,000. We encourage candidates of all levels to apply as there is often flexibility on job title and responsibilities. Compensation will be based on a variety of factors, including experience, qualifications, internal equity and location. Lyterian offers a competitive employment package that includes an annual bonus, significant equity, and a generous benefits package including comprehensive health, dental, and vision insurance for our employees and their families, plus a 401K match. Seniority level
Seniority level Not Applicable Employment type
Employment type Full-time Job function
Job function Research, Analyst, and Information Technology Referrals increase your chances of interviewing at Lyterian Therapeutics by 2x Get notified about new Chemist jobs in
San Francisco Bay Area . Concord, CA $70,000.00-$75,000.00 1 week ago Fremont, CA $110,000.00-$115,000.00 1 week ago South San Francisco, CA $28.00-$32.00 4 days ago AI Trainer for Analytical Chemistry (Freelance, Remote)
Hayward, CA $85,000.00-$100,000.00 2 weeks ago South San Francisco, CA $100,000.00-$130,000.00 3 days ago Hayward, CA $125,000.00-$150,000.00 6 days ago San Mateo County, CA $57.00-$57.00 2 weeks ago Menlo Park, CA $100,000.00-$150,000.00 2 weeks ago Analytical Chemistry Research Associate II-III
Hayward, CA $75,000.00-$105,000.00 1 month ago Hayward, CA $90,000.00-$115,000.00 2 days ago Research Assistant, Materials Chemistry (Nanoparticles)
Scientist/Senior Scientist, Analytical Chemistry
Newark, CA $150,000.00-$175,000.00 5 days ago Fremont, CA $75,000.00-$85,000.00 2 weeks ago Scientist/Senior Scientist, Analytical Chemistry
San Mateo County, CA $75.00-$85.00 1 week ago Research Scientist - Computational Chemistry
Oakland, CA $150,000.00-$200,000.00 1 month ago Polymer Formulation & Characterization - Scientist I-III/Senior/Lead
Alameda, CA $110,000.00-$180,000.00 1 week ago Scientist, Analytical Development and Quality Control
We’re unlocking community knowledge in a new way. Experts add insights directly into each article, started with the help of AI.
#J-18808-Ljbffr