Pfizer
Senior Associate Scientist - LCMS Biomeasures
Pfizer, Andover, Massachusetts, United States, 01810
Senior Associate Scientist
Everything we do, every day, is in line with an unwavering commitment to the quality and the delivery of safe and effective products to patients. Our science and risk-based compliant quality culture is flexible, innovative, and customer oriented. Whether you are involved in development, maintenance, compliance or analysis through research programs, your contribution will directly impact patients. Are you a bioanalytical scientist interested in contributing to the field of quantitative protein mass spectrometry? Join us as a Senior Associate Scientist on the Biomeasures LCMS team at Pfizer located in Andover, MA. You will be contributing to all aspects of development, implementation, execution, and analysis of high sensitivity LCMS assays for protein target quantification across the Pfizer portfolio in multiple matrices (serum, plasma, tissues, extracellular vesicles, etc) using state-of-the-art enrichment and instrumental techniques. This is a great opportunity to broadly apply your growing expertise to emerging areas of bioanalysis and impact a wide range of novel drug modalities with a particular focus on development of LCMS assays intended for clinical utility. Responsible for developing advanced sample preparation and instrumental techniques across multiple biological matrices in all therapeutic areas with a particular focus on development of LCMS assays intended for clinical utility Drive experimentation and adoption of novel, optimized workflows to solve complex problems and expand our group's analytical processes and capabilities Communicate your scientific findings effectively to various audiences in the form of well-organized presentations and publications Collaborate both internally and externally to develop successful partnerships in a large, matrix environment Participate in all phases of mass spectrometry laboratory operations including instrument maintenance, the development of sample preparation and separation methods, data analysis, etc Take keen interest, responsibility, and ownership for portions of our workflows that stoke your scientific curiosity Ensure all tasks and responsibilities are carried out according to scientific and ethical standards BS with 3+ years of bioanalytical experience OR a MS with 0+ bioanalytical experience Expertise in biological sample preparation techniques (immunoaffinity, tryptic digestion, tissue processing, conjugation, etc) of various biofluids Experience with general quantitative analysis techniques and statistical approaches Experience generating scientific collateral using Microsoft Office applications and presenting findings to audiences effectively Ability to multitask as both an independent contributor and an influential team member Experience in the operation and maintenance of LCMS instrumentation and associated data analysis software (Skyline, Xcalibur, etc) Working understanding of protein biochemistry and quantitative protein analytical techniques Prior industry experience including history of successful outsourcing of LCMS assays to CRO partners Ability to meet the standard requirements for a lab-based role and perform all typical lab related activities (lifting ?20 pounds, frequent pipetting, long stretches on feet, etc) Occasional travel to Cambridge (Kendal Square) may be required, depending on project needs Last Date to Apply: July 08, 2025. Work Location Assignment: On Premise No relocation Support Available The annual base salary for this position ranges from $66,500.00 to $110,900.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 7.5% of the base salary. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States. Relocation assistance may be available based on business needs and/or eligibility.
Everything we do, every day, is in line with an unwavering commitment to the quality and the delivery of safe and effective products to patients. Our science and risk-based compliant quality culture is flexible, innovative, and customer oriented. Whether you are involved in development, maintenance, compliance or analysis through research programs, your contribution will directly impact patients. Are you a bioanalytical scientist interested in contributing to the field of quantitative protein mass spectrometry? Join us as a Senior Associate Scientist on the Biomeasures LCMS team at Pfizer located in Andover, MA. You will be contributing to all aspects of development, implementation, execution, and analysis of high sensitivity LCMS assays for protein target quantification across the Pfizer portfolio in multiple matrices (serum, plasma, tissues, extracellular vesicles, etc) using state-of-the-art enrichment and instrumental techniques. This is a great opportunity to broadly apply your growing expertise to emerging areas of bioanalysis and impact a wide range of novel drug modalities with a particular focus on development of LCMS assays intended for clinical utility. Responsible for developing advanced sample preparation and instrumental techniques across multiple biological matrices in all therapeutic areas with a particular focus on development of LCMS assays intended for clinical utility Drive experimentation and adoption of novel, optimized workflows to solve complex problems and expand our group's analytical processes and capabilities Communicate your scientific findings effectively to various audiences in the form of well-organized presentations and publications Collaborate both internally and externally to develop successful partnerships in a large, matrix environment Participate in all phases of mass spectrometry laboratory operations including instrument maintenance, the development of sample preparation and separation methods, data analysis, etc Take keen interest, responsibility, and ownership for portions of our workflows that stoke your scientific curiosity Ensure all tasks and responsibilities are carried out according to scientific and ethical standards BS with 3+ years of bioanalytical experience OR a MS with 0+ bioanalytical experience Expertise in biological sample preparation techniques (immunoaffinity, tryptic digestion, tissue processing, conjugation, etc) of various biofluids Experience with general quantitative analysis techniques and statistical approaches Experience generating scientific collateral using Microsoft Office applications and presenting findings to audiences effectively Ability to multitask as both an independent contributor and an influential team member Experience in the operation and maintenance of LCMS instrumentation and associated data analysis software (Skyline, Xcalibur, etc) Working understanding of protein biochemistry and quantitative protein analytical techniques Prior industry experience including history of successful outsourcing of LCMS assays to CRO partners Ability to meet the standard requirements for a lab-based role and perform all typical lab related activities (lifting ?20 pounds, frequent pipetting, long stretches on feet, etc) Occasional travel to Cambridge (Kendal Square) may be required, depending on project needs Last Date to Apply: July 08, 2025. Work Location Assignment: On Premise No relocation Support Available The annual base salary for this position ranges from $66,500.00 to $110,900.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 7.5% of the base salary. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States. Relocation assistance may be available based on business needs and/or eligibility.