Kite Pharma
Scientist, Analytical Operations - Cell Therapy
Kite Pharma, Santa Monica, California, United States, 90404
Job Overview
Attribute Sciences is seeking a talented and highly motivated Scientist, Analytical Operations with a background in immunology, cell biology, and/or cancer biology. The ideal candidate will have experience in using flow cytometry and cell-based in vitro assays to assess the functional phenotype of immune cells. The Scientist, Analytical Operations will perform innovative characterization studies to interrogate quality attributes of Kite's cell therapy products. In addition, the Scientist, Analytical Operations will be responsible for developing characterization methods that will be used from early-stage development through commercialization. The Scientist, Analytical Operations will collaborate cross-functionally with Process Design, Research, Translational Medicine, and/or Quality teams in an effort to enable in-process attribute and product understanding. The ideal candidate should be adaptable and willing to accept new roles and responsibilities that could evolve over time. Responsibilities Include But Are Not Limited To:
Design and execution of phase-appropriate characterization studies, including but not limited to cell-based assays and immunoassays to interrogate immune cell biology and function. Multi-parameter flow cytometry method design and demonstrated application to interrogating functional phenotype of immune cells. Handling and maintenance of associated materials, such as cells and reagents, in an established and controlled manner. Generation, analysis, interpretation, documentation and presentation of experimental data. Author, review, and edit technical documents, i.e. SOPs and/or reports. Basic Requirements:
Ph.D. in Biology, Immunology or related discipline with 0+ years of industry experience, or M.S. in Biology, Immunology or related discipline with 3+ years of industry experience, or B.S. in Biology, Immunology or related discipline with 5+ years of industry experience, or High School Diploma with 9+ years of related industry experience. Additional Qualifications: Expertise with cell surface and intracellular profiling using flow cytometry; experience with spectral flow is a plus. Experience and technical understanding of ELISA, MSD, Luminex, Incucyte, Seahorse, and/or ddPCR. Experience with cell culture (aseptic techniques, human cell line expansion); experience with human primary cell culture and isolation of immune cells from multiple tissues is preferred. Experience with single-cell molecular techniques is a plus. i.e. genomics, transcriptomics, and/or proteomics. Strong ability to proficient use of Microsoft Office, data analysis software (Prism, JMP) and/or other applications. Strong scientific writing and presentation skills. Ability to design experiments and analyze data. Ability to think critically and demonstrate troubleshooting and problem-solving skills. Excellent organizational skills. Ability to navigate change and evolving priorities. Excellent ability to develop relationships, manage stakeholders and work cross-functionally. Ability to mentor junior scientific staff. The salary range for this position is: $133,195.00 - $172,370.00. Kite considers a variety of factors when determining base compensation, including experience, qualifications, and geographic location. These considerations mean actual compensation will vary. This position may also be eligible for a discretionary annual bonus, discretionary stock-based long-term incentives (eligibility may vary based on role), paid time off, and a benefits package. Kite is a biopharmaceutical company engaged in the development of innovative cancer immunotherapies with a goal of providing rapid, long-term durable response and eliminating the burden of chronic care. The company is focused on chimeric antigen receptor (CAR) and T cell receptor (TCR) engineered cell therapies designed to empower the immune system's ability to recognize and kill tumors. Kite is based in Santa Monica, CA. Kite Pharma is committed to providing equal employment opportunities to all employees and applicants for employment, and is dedicated to fostering an inclusive work environment comprised of diverse perspectives, backgrounds, and experiences. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, sex, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. Our environment respects individual differences and recognizes each employee as an integral member of our company. Our workforce reflects these values and celebrates the individuals who make up our growing team. Kite Pharma provides a work environment free of harassment and prohibited conduct. We promote and support individual differences and diversity of thoughts and opinion.
Attribute Sciences is seeking a talented and highly motivated Scientist, Analytical Operations with a background in immunology, cell biology, and/or cancer biology. The ideal candidate will have experience in using flow cytometry and cell-based in vitro assays to assess the functional phenotype of immune cells. The Scientist, Analytical Operations will perform innovative characterization studies to interrogate quality attributes of Kite's cell therapy products. In addition, the Scientist, Analytical Operations will be responsible for developing characterization methods that will be used from early-stage development through commercialization. The Scientist, Analytical Operations will collaborate cross-functionally with Process Design, Research, Translational Medicine, and/or Quality teams in an effort to enable in-process attribute and product understanding. The ideal candidate should be adaptable and willing to accept new roles and responsibilities that could evolve over time. Responsibilities Include But Are Not Limited To:
Design and execution of phase-appropriate characterization studies, including but not limited to cell-based assays and immunoassays to interrogate immune cell biology and function. Multi-parameter flow cytometry method design and demonstrated application to interrogating functional phenotype of immune cells. Handling and maintenance of associated materials, such as cells and reagents, in an established and controlled manner. Generation, analysis, interpretation, documentation and presentation of experimental data. Author, review, and edit technical documents, i.e. SOPs and/or reports. Basic Requirements:
Ph.D. in Biology, Immunology or related discipline with 0+ years of industry experience, or M.S. in Biology, Immunology or related discipline with 3+ years of industry experience, or B.S. in Biology, Immunology or related discipline with 5+ years of industry experience, or High School Diploma with 9+ years of related industry experience. Additional Qualifications: Expertise with cell surface and intracellular profiling using flow cytometry; experience with spectral flow is a plus. Experience and technical understanding of ELISA, MSD, Luminex, Incucyte, Seahorse, and/or ddPCR. Experience with cell culture (aseptic techniques, human cell line expansion); experience with human primary cell culture and isolation of immune cells from multiple tissues is preferred. Experience with single-cell molecular techniques is a plus. i.e. genomics, transcriptomics, and/or proteomics. Strong ability to proficient use of Microsoft Office, data analysis software (Prism, JMP) and/or other applications. Strong scientific writing and presentation skills. Ability to design experiments and analyze data. Ability to think critically and demonstrate troubleshooting and problem-solving skills. Excellent organizational skills. Ability to navigate change and evolving priorities. Excellent ability to develop relationships, manage stakeholders and work cross-functionally. Ability to mentor junior scientific staff. The salary range for this position is: $133,195.00 - $172,370.00. Kite considers a variety of factors when determining base compensation, including experience, qualifications, and geographic location. These considerations mean actual compensation will vary. This position may also be eligible for a discretionary annual bonus, discretionary stock-based long-term incentives (eligibility may vary based on role), paid time off, and a benefits package. Kite is a biopharmaceutical company engaged in the development of innovative cancer immunotherapies with a goal of providing rapid, long-term durable response and eliminating the burden of chronic care. The company is focused on chimeric antigen receptor (CAR) and T cell receptor (TCR) engineered cell therapies designed to empower the immune system's ability to recognize and kill tumors. Kite is based in Santa Monica, CA. Kite Pharma is committed to providing equal employment opportunities to all employees and applicants for employment, and is dedicated to fostering an inclusive work environment comprised of diverse perspectives, backgrounds, and experiences. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, sex, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. Our environment respects individual differences and recognizes each employee as an integral member of our company. Our workforce reflects these values and celebrates the individuals who make up our growing team. Kite Pharma provides a work environment free of harassment and prohibited conduct. We promote and support individual differences and diversity of thoughts and opinion.