Hispanic Alliance for Career Enhancement
Advisor/Sr. Advisor - Macrocycles Chemical Biology
Hispanic Alliance for Career Enhancement, Pasadena, California, United States, 91104
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees work to discover and bring medicines to those in need, improve disease understanding, and give back through philanthropy and volunteerism. We prioritize our work and put people first. We seek individuals committed to improving lives globally.
If you would like to know a bit more about this opportunity, or are considering applying, then please read the following job information. About the Protomer Team The Protomer team focuses on chemical biology, molecular switches, and (oral) peptidic macrocycles platforms. This role emphasizes deep technology development in chemical biology, especially peptides and macrocycles, with a focus on peptide libraries and oral macrocyclic peptides.
The team engages in disease-relevant biological systems to test Lilly's pipeline of medicines. The candidate will help develop strategy, manage scientific milestones, and contribute to long-term planning.
Candidate Profile The ideal candidate is a significant contributor and leader within a collaborative team, capable of managing scientific portfolios, supporting business objectives, and mentoring junior scientists. Proven success in similar roles with a track record of leading scientific rationale, planning, and execution is essential. The candidate should be able to independently lead projects, shape team strategy, and foster cross-functional relationships across therapeutic areas such as diabetes, neuroscience, immunology, and oncology.
Responsibilities
Contribute to projects involving oral macrocycles, chemical biology, or peptide frameworks, focusing on molecule design and conjugation.
Work on molecule engineering from lead identification to optimization, supporting phases 1b and beyond.
Lead screening efforts for lead discovery and optimization of oral macrocyclic peptides.
Enhance platform technology efforts to accelerate lead finding and optimization.
Collaborate within the group, provide independent scientific insights, and contribute to strategy and execution.
Drive molecular engineering efforts towards high-conviction targets, promoting speed and prioritization.
Inspire collaboration and innovation in medicine development, maintaining high scientific standards and safety.
Promote diversity and inclusion, and support the development of scientists.
Work professionally and responsibly with colleagues across Lilly.
Qualifications PhD or post-doctoral degree in chemistry, chemical biology, or related fields, with significant research experience and a successful track record.
Knowledge of oral macrocyclic peptides, library-based screening, and biophysical/biochemical properties.
Experience with bioinformatics, NGS analysis, peptide library design, and molecular biology techniques.
Familiarity with lab automation, computational tools, and AI/ML techniques for drug development.
Understanding of the drug discovery process, including lead optimization, and ability to collaborate across functional groups.
Excellent communication, teamwork, problem-solving skills, and strategic thinking.
Additional Information
Some domestic and international travel expected.
Equal opportunity employer committed to diversity and inclusion.
Accommodation support available for applicants with disabilities.
Salary range: $133,500 - $217,800, plus benefits and bonuses.
Learn more about our employee resource groups and benefits on our careers page.
#J-18808-Ljbffr
If you would like to know a bit more about this opportunity, or are considering applying, then please read the following job information. About the Protomer Team The Protomer team focuses on chemical biology, molecular switches, and (oral) peptidic macrocycles platforms. This role emphasizes deep technology development in chemical biology, especially peptides and macrocycles, with a focus on peptide libraries and oral macrocyclic peptides.
The team engages in disease-relevant biological systems to test Lilly's pipeline of medicines. The candidate will help develop strategy, manage scientific milestones, and contribute to long-term planning.
Candidate Profile The ideal candidate is a significant contributor and leader within a collaborative team, capable of managing scientific portfolios, supporting business objectives, and mentoring junior scientists. Proven success in similar roles with a track record of leading scientific rationale, planning, and execution is essential. The candidate should be able to independently lead projects, shape team strategy, and foster cross-functional relationships across therapeutic areas such as diabetes, neuroscience, immunology, and oncology.
Responsibilities
Contribute to projects involving oral macrocycles, chemical biology, or peptide frameworks, focusing on molecule design and conjugation.
Work on molecule engineering from lead identification to optimization, supporting phases 1b and beyond.
Lead screening efforts for lead discovery and optimization of oral macrocyclic peptides.
Enhance platform technology efforts to accelerate lead finding and optimization.
Collaborate within the group, provide independent scientific insights, and contribute to strategy and execution.
Drive molecular engineering efforts towards high-conviction targets, promoting speed and prioritization.
Inspire collaboration and innovation in medicine development, maintaining high scientific standards and safety.
Promote diversity and inclusion, and support the development of scientists.
Work professionally and responsibly with colleagues across Lilly.
Qualifications PhD or post-doctoral degree in chemistry, chemical biology, or related fields, with significant research experience and a successful track record.
Knowledge of oral macrocyclic peptides, library-based screening, and biophysical/biochemical properties.
Experience with bioinformatics, NGS analysis, peptide library design, and molecular biology techniques.
Familiarity with lab automation, computational tools, and AI/ML techniques for drug development.
Understanding of the drug discovery process, including lead optimization, and ability to collaborate across functional groups.
Excellent communication, teamwork, problem-solving skills, and strategic thinking.
Additional Information
Some domestic and international travel expected.
Equal opportunity employer committed to diversity and inclusion.
Accommodation support available for applicants with disabilities.
Salary range: $133,500 - $217,800, plus benefits and bonuses.
Learn more about our employee resource groups and benefits on our careers page.
#J-18808-Ljbffr