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Regeneron

Scientist- Biomolecular Interactions/Kinetics

Regeneron, Tarrytown, New York, United States, 10591

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Scientist

We are seeking a motivated Scientist to join the High Throughput Antibody Screening and Biomolecular Interaction Group within the Therapeutic Proteins team. You will support Therapeutics Protein activities by implementing methods to characterize protein interaction kinetics and biochemical properties using SPR, BLI, ITC, and other analytical technologies in support of our VelocImmune fully-human antibody pipeline. As a Scientist, a typical day might include: Conducting experiments including antibody characterization, method development, and analytical support for biologics development using biochemical and biophysical methods Troubleshooting established test methods used in development and release testing of screening reagents Tabulating results and writing summary reports of assay development Presenting findings at group and interdepartmental meetings Maintaining lab supplies and equipment This role might be for you if you: Can work independently, show initiative to design and carry out experiments based on protocols Manage and organize data independently, as well as have decision-making capabilities but know when to reach out for support Can troubleshoot methodological and technical issues Enjoy working in a fast-paced and deadline driven team environment and are capable of multi-tasking across assignments Have excellent communication skills In order to be considered for this role, you must have at least a BS/MS with 6+ years of relevant lab experience. We need someone with a foundational knowledge in structural biology, biophysics, or chemical biology. Must have experience in protein chemistry techniques (HPLC, FLPC, ion-exchange, affinity, size exclusion chromatography, and protein conjugation chemistry) and protein analysis (SDS-PAGE, Western-blot, ELISA). Knowledge and experience in using biophysical methodologies such as Biacore, Octet, or ITC to study protein/small molecule or protein/protein interactions and binding kinetics is required.