Thermo Fisher Scientific
Upstream/Downstream Process Development Scientist I
Thermo Fisher Scientific, Plainville, Massachusetts, us, 02762
Upstream/Downstream Process Development Scientist I
Join to apply for the
Upstream/Downstream Process Development Scientist I
role at
Thermo Fisher Scientific Upstream/Downstream Process Development Scientist I
Join to apply for the
Upstream/Downstream Process Development Scientist I
role at
Thermo Fisher Scientific Get AI-powered advice on this job and more exclusive features. Work Schedule
Standard (Mon-Fri)
Environmental Conditions
Laboratory Setting
Thermo Fisher Scientific Inc. is the world leader in serving science, with annual revenue exceeding $35 billion. Whether our customers are accelerating life sciences research, solving complex analytical challenges, improving patient diagnostics and therapies or increasing efficiency in their laboratories, we are here to support them.
At Viral Vector Services (VVS) a division of Thermo Fisher Scientific, we deliver from process development through commercial supply, we offer the expertise and resources to help clients deliver innovative gene therapies.
Job Title: Scientist I Process Development-Upstream or Downstream
Location/Division Specific Information : US - Massachusetts – Plainville (on-site)
How will you make an impact?
As the Upstream/Downstream Process Development Scientist you will help our clients to deliver lifesaving and life changing therapies to patients in need. You will be supporting planning, executing, and documenting laboratory and tech transfer activities in support of process establishment, pilot, and transfer into cGMP manufacturing. You will also act as a subject matter expert (SME) and support transfer and operation of internally developed and client-transferred processes into the process development and pilot space. You will also be supporting tech transfer out to the cGMP manufacturing space.
Education regiments:
B.S. in Chemical Engineering, Biochemistry, Biology or related field
General qualifications:
Demonstrated understanding of experimental design with the ability to independently conduct laboratory experiments. Collaborate with the Analytical Development team to develop comprehensive testing plans. Participate in client meetings to present results and assist with drafting process development reports. Prepare Process Development records, work instructions, and batch records. Proficiency in technical writing, adhering to Good Documentation Practices (GDP), with preferred experience in data compilation and interpretation. Strong communication skills with the ability to clearly and concisely interpret, summarize, and present scientific data. Flexibility in work hours, including availability for weekends and evenings, as the need arises to meet project timelines.
Upstream Process Development Qualifications:
Practical experience in aseptic techniques, cell culture, single-use bioreactors (SUBs), wave reactors, and harvest/clarification processes is preferred. Familiarity with transfection and infection -based processes for gene therapy production
Downstream Process Development Qualifications:
Expertise in various purification techniques, including affinity and anion exchange chromatography, with proficiency in using AKTA chromatography systems and Unicorn software is helpful. Experience with filtration-based unit operations such as tangential flow filtration, sterile filtration, and depth filtration is helpful.
Knowledge, Skills, Abilities
Ability to analyze and summarize scientific data Understanding of cGMP and regulatory requirements of biopharmaceutical manufacturing. Strong interpersonal and communications skills; written and oral Ability to function in a constantly evolving environment & balance multiple priorities. A flexible work schedule is required including Weekend and night as needed to support lab activities.
Seniority level
Seniority level Not Applicable Employment type
Employment type Full-time Job function
Job function Research, Science, and Engineering Industries Pharmaceutical Manufacturing and Biotechnology Research Referrals increase your chances of interviewing at Thermo Fisher Scientific by 2x Get notified about new Process Development Scientist jobs in
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Join to apply for the
Upstream/Downstream Process Development Scientist I
role at
Thermo Fisher Scientific Upstream/Downstream Process Development Scientist I
Join to apply for the
Upstream/Downstream Process Development Scientist I
role at
Thermo Fisher Scientific Get AI-powered advice on this job and more exclusive features. Work Schedule
Standard (Mon-Fri)
Environmental Conditions
Laboratory Setting
Thermo Fisher Scientific Inc. is the world leader in serving science, with annual revenue exceeding $35 billion. Whether our customers are accelerating life sciences research, solving complex analytical challenges, improving patient diagnostics and therapies or increasing efficiency in their laboratories, we are here to support them.
At Viral Vector Services (VVS) a division of Thermo Fisher Scientific, we deliver from process development through commercial supply, we offer the expertise and resources to help clients deliver innovative gene therapies.
Job Title: Scientist I Process Development-Upstream or Downstream
Location/Division Specific Information : US - Massachusetts – Plainville (on-site)
How will you make an impact?
As the Upstream/Downstream Process Development Scientist you will help our clients to deliver lifesaving and life changing therapies to patients in need. You will be supporting planning, executing, and documenting laboratory and tech transfer activities in support of process establishment, pilot, and transfer into cGMP manufacturing. You will also act as a subject matter expert (SME) and support transfer and operation of internally developed and client-transferred processes into the process development and pilot space. You will also be supporting tech transfer out to the cGMP manufacturing space.
Education regiments:
B.S. in Chemical Engineering, Biochemistry, Biology or related field
General qualifications:
Demonstrated understanding of experimental design with the ability to independently conduct laboratory experiments. Collaborate with the Analytical Development team to develop comprehensive testing plans. Participate in client meetings to present results and assist with drafting process development reports. Prepare Process Development records, work instructions, and batch records. Proficiency in technical writing, adhering to Good Documentation Practices (GDP), with preferred experience in data compilation and interpretation. Strong communication skills with the ability to clearly and concisely interpret, summarize, and present scientific data. Flexibility in work hours, including availability for weekends and evenings, as the need arises to meet project timelines.
Upstream Process Development Qualifications:
Practical experience in aseptic techniques, cell culture, single-use bioreactors (SUBs), wave reactors, and harvest/clarification processes is preferred. Familiarity with transfection and infection -based processes for gene therapy production
Downstream Process Development Qualifications:
Expertise in various purification techniques, including affinity and anion exchange chromatography, with proficiency in using AKTA chromatography systems and Unicorn software is helpful. Experience with filtration-based unit operations such as tangential flow filtration, sterile filtration, and depth filtration is helpful.
Knowledge, Skills, Abilities
Ability to analyze and summarize scientific data Understanding of cGMP and regulatory requirements of biopharmaceutical manufacturing. Strong interpersonal and communications skills; written and oral Ability to function in a constantly evolving environment & balance multiple priorities. A flexible work schedule is required including Weekend and night as needed to support lab activities.
Seniority level
Seniority level Not Applicable Employment type
Employment type Full-time Job function
Job function Research, Science, and Engineering Industries Pharmaceutical Manufacturing and Biotechnology Research Referrals increase your chances of interviewing at Thermo Fisher Scientific by 2x Get notified about new Process Development Scientist jobs in
Plainville, MA . Framingham, MA $84,000.00-$121,333.33 2 weeks ago Framingham, MA $100,500.00-$145,166.66 3 days ago Framingham, MA $100,500.00-$145,166.66 1 day ago Research Scientist I, Analytical Development
Milford, MA $84,400.00-$103,300.00 3 hours ago Wellesley Hills, MA $111,240.00-$222,480.00 1 month ago Massachusetts, United States $170,000.00-$215,000.00 1 week ago Senior Research Computing Data Scientist
Massachusetts, United States $87,210.00-$131,230.00 3 weeks ago Massachusetts, United States $87,210.00-$131,230.00 3 weeks ago Coventry, RI $100,000.00-$130,000.00 1 week ago Senior Scientist, Analytical Quality Control
Senior Medical Lab Scientist, Chemistry - Dayshift
Senior Environmental Scientist/Geologist
Massachusetts, United States $70,900.00-$102,900.00 3 weeks ago Senior Medical Lab Scientist, Hematology - Dayshift
Senior Medical Lab Scientist, Microbiology -Dayshift
Massachusetts, United States $148,000.00-$287,500.00 3 days ago Westborough, MA $110,000.00-$120,000.00 2 weeks ago Scientist, Downstream Process Development in MSAT
Senior Scientist, Antibody Discovery & Characterization
Massachusetts, United States 3 months ago Senior Scientist / Manager, Analytical Development
Senior Research Scientist - Material Flammability, Fire Dynamics and Lithium-ion Battery Safety
Research Scientist / Senior Research Scientist, Assay Discovery
Scientist, Cardio-Renal Department, Kidney Group
Massachusetts, United States $77,100.00-$128,500.00 8 hours ago Senior Scientist, Applied Machine Learning and Generative AI, Pharma R&D (2)
Wellesley Hills, MA $106,605.00-$206,000.00 1 month ago Senior Data Scientist - Pharmacy Operations
Wellesley Hills, MA $111,240.00-$222,480.00 1 month ago We’re unlocking community knowledge in a new way. Experts add insights directly into each article, started with the help of AI.
#J-18808-Ljbffr