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Katalyst CRO

Regulatory Affairs Specialist II

Katalyst CRO, Alameda, California, United States, 94501

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Katalyst CRO Responsibilities include developing regulatory strategies, reviewing design input/output documentation, identification of applicable standards and guidance documents, performing regulatory assessments to determine the impact of design/process changes, preparing regulatory submissions, maintaining regulatory filings and licenses and interacting with regulatory agencies. Serve as the global regulatory liaison and primary point of contact for product and project teams for Paragon 28 software applications and surgical system hardware. Maintain expert knowledge of appropriate regulations, legislation, best practices, and guidelines related to Artificial Intelligence, Software as a Medical Device and Machine Learning (SaMD/ML). Provide regulatory guidance to product teams, develop regulatory strategies, and review and approve product design control documentation. Determine regulatory pathways and formulate regulatory strategies for the U.S. market. Assess regulatory impact on design, materials, labeling, packaging, manufacturing processes, and facility changes. FDA 510(k) premarket notifications, De Novo applications, internal Letters to File, and pre-submissions, with minimal supervision. Coordinate with technical experts to provide additional data/information requested by regulatory agencies and prepare responses to facilitate regulatory approvals. Provide risk-based guidance and regulatory input to projects and issues, ensuring cross-functional alignment and resolution. Collaborate with international counterparts to support global regulatory submissions, approvals, and implementation rollouts. Build relationships and interface with cross-functional teams (Engineering, Manufacturing, Marketing, etc.). Build and conduct regular training in software development, software as a medical device and cybersecurity. Assess impact of changes to applicable laws and regulations and identify impact to the business and in collaboration with other stakeholders, develop strategies to address such changes. Support responses to regulatory body inquiries and support audits by regulatory bodies. Review and understand global regulatory requirements (FDA, TGA, EU MDD, MDR, Health Canada, etc.) Provide mentoring to junior level positions.

Responsibilities

Responsibilities include developing regulatory strategies, reviewing design input/output documentation, identification of applicable standards and guidance documents, performing regulatory assessments to determine the impact of design/process changes, preparing regulatory submissions, maintaining regulatory filings and licenses and interacting with regulatory agencies. Serve as the global regulatory liaison and primary point of contact for product and project teams for Paragon 28 software applications and surgical system hardware. Maintain expert knowledge of appropriate regulations, legislation, best practices, and guidelines related to Artificial Intelligence, Software as a Medical Device and Machine Learning (SaMD/ML). Provide regulatory guidance to product teams, develop regulatory strategies, and review and approve product design control documentation. Determine regulatory pathways and formulate regulatory strategies for the U.S. market. Assess regulatory impact on design, materials, labeling, packaging, manufacturing processes, and facility changes. FDA 510(k) premarket notifications, De Novo applications, internal Letters to File, and pre-submissions, with minimal supervision. Coordinate with technical experts to provide additional data/information requested by regulatory agencies and prepare responses to facilitate regulatory approvals. Provide risk-based guidance and regulatory input to projects and issues, ensuring cross-functional alignment and resolution. Collaborate with international counterparts to support global regulatory submissions, approvals, and implementation rollouts. Build relationships and interface with cross-functional teams (Engineering, Manufacturing, Marketing, etc.). Build and conduct regular training in software development, software as a medical device and cybersecurity. Assess impact of changes to applicable laws and regulations and identify impact to the business and in collaboration with other stakeholders, develop strategies to address such changes. Support responses to regulatory body inquiries and support audits by regulatory bodies. Review and understand global regulatory requirements (FDA, TGA, EU MDD, MDR, Health Canada, etc.) Provide mentoring to junior level positions.

Requirements:

Bachelor's degree (Engineering, Biology, or Regulatory Science) and a minimum of 3+ year(s) related experience; or equivalent combination of education and experience. Proven experience with software as a medical device (SaMD) and mobile health app regulations. In-depth knowledge of FDA guidance on digital health, cybersecurity, and mobile medical apps. Track record of 510(k)/De Novo submissions for connected orthopedic or wearable devices. Familiarity with IEC 62304, ISO 13485, and FDA Part 11 compliance for software validation. Experience with EU MDR requirements for software and app-based devices (Annex I & XIII). Effective collaboration with software, clinical, and human factors team. Post-market compliance expertise, including UDI, vigilance, and software change reporting. Strong understanding of cybersecurity requirements and guidance (e.g., FDA, IMDRF). Knowledge of US and/or international regulatory requirements (FDA, TGA, EU MDD, MDR, Health Canada, etc.). Direct experience with regulatory submissions for Artificial Intelligence, Software as a Medical Device and Machine Learning (SaMD/ML) products. Excellent attention to detail and proven organizational skills, able to prioritize and multi-task and see projects/assignments to completion. Proficiency in Excel, Word, PowerPoint, Outlook and customer database management systems. Proven leadership and negotiation skills, works well with all levels, able to successfully manage cross-departmental expectations. Excellent written and verbal communication skills. Seniority level

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