Gilead
Postdoctoral Scientist, Structural Biology
Gilead, San Mateo, California, United States, 94404
Gilead Sciences Postdoctoral Scientist
At Gilead, we're creating a healthier world for all people. For more than 35 years, we've tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer
working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world's biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference. Every member of Gilead's team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we're looking for the next wave of passionate and ambitious people ready to make a direct impact. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together. The Structural Biology Group at Gilead Sciences is seeking a highly motivated postdoctoral scientist to join our program at the Foster City campus. The Structural Biology Group is well equipped with an advanced X-ray crystallography laboratory and a state-of-the-art cryo-EM facility hosting a Glacios and a Krios G4 microscopes. The group provides critical structural information to elucidate the mechanism of action and to facilitate lead molecule optimization, and supports diverse drug discovery projects spanning virology, inflammation, and oncology. This postdoc position will be utilizing protein biochemistry, biophysics, and structural biology techniques to elucidate the molecular mechanism of important drug targets including both small molecule and biologics programs. As part of the training, the candidate will also contribute to new cryo-EM methods development and implementation. The successful candidate is expected to have a solid training in single particle cryo-EM and strong scientific experience as evidenced by first-author publications in top-tier scientific journals. Responsibilities: Construct design, protein expression and purification for structural studies. Cryo-EM sample preparation & optimization, data collection and structure determination of target complexes. Basic Qualifications: Candidates must have Ph.D in structural biology, biochemistry, or a related field. Preferred Qualifications: Experience in laboratory techniques supporting structural biology and recombinant protein purification, membrane protein experience is highly desired. Strong communication and interpersonal skills, and the ability to work flexibly in a dynamic and collaborative environment. Demonstrated a strong track record of independent critical thinking and scientific achievement in research, exemplified by publications in highly regarded journals, conference presentations or generation of intellectual property.
At Gilead, we're creating a healthier world for all people. For more than 35 years, we've tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer
working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world's biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference. Every member of Gilead's team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we're looking for the next wave of passionate and ambitious people ready to make a direct impact. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together. The Structural Biology Group at Gilead Sciences is seeking a highly motivated postdoctoral scientist to join our program at the Foster City campus. The Structural Biology Group is well equipped with an advanced X-ray crystallography laboratory and a state-of-the-art cryo-EM facility hosting a Glacios and a Krios G4 microscopes. The group provides critical structural information to elucidate the mechanism of action and to facilitate lead molecule optimization, and supports diverse drug discovery projects spanning virology, inflammation, and oncology. This postdoc position will be utilizing protein biochemistry, biophysics, and structural biology techniques to elucidate the molecular mechanism of important drug targets including both small molecule and biologics programs. As part of the training, the candidate will also contribute to new cryo-EM methods development and implementation. The successful candidate is expected to have a solid training in single particle cryo-EM and strong scientific experience as evidenced by first-author publications in top-tier scientific journals. Responsibilities: Construct design, protein expression and purification for structural studies. Cryo-EM sample preparation & optimization, data collection and structure determination of target complexes. Basic Qualifications: Candidates must have Ph.D in structural biology, biochemistry, or a related field. Preferred Qualifications: Experience in laboratory techniques supporting structural biology and recombinant protein purification, membrane protein experience is highly desired. Strong communication and interpersonal skills, and the ability to work flexibly in a dynamic and collaborative environment. Demonstrated a strong track record of independent critical thinking and scientific achievement in research, exemplified by publications in highly regarded journals, conference presentations or generation of intellectual property.