VP and Head Clinical Operations, CVRM

Join to apply for the VP and Head Clinical Operations, CVRM role at AstraZeneca

Join to apply for the VP and Head Clinical Operations, CVRM role at AstraZeneca

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Possible locations: Boston, MA, Gaithersburg, MD, Cambridge (UK), Gothenburg (Sweden), Mississauga (Canada)
Are you ready to lead and inspire a global team in the pursuit of life-changing therapies? We are seeking a visionary VP and Head of Clinical Operations for CVRM (Cardiovascular, Renal, and Metabolic) to drive our clinical operations strategy and execution. As a key member of the Global Clinical Operations leadership team, you will oversee the delivery of therapeutic programs on a global scale, ensuring they meet time, cost, and quality benchmarks. With your deep therapeutic expertise and entrepreneurial mindset, you'll thrive in our science-driven environment, collaborating with SVPs, therapy area leads, and various teams to align CVRM strategies and priorities.
Accountabilities

• Provide clear portfolio-level clinical operations expertise to Early and Late TA leadership teams and other internal partners.
• Develop, maintain, and implement an operational CVRM strategy with input from internal and external experts.
• Establish and direct strategic global leadership for the CVRM Clinical Operations group.
• Ensure delivery of operational and clinical development components across the global clinical programs.
• Build strong relationships with Senior Vice Presidents of Early and Late CVRM.
• Lead all aspects of global delivery of R&D phase I-III clinical trials for the CVRM portfolio.
• Collaborate closely with GPT/CPT colleagues around submission strategy.
• Communicate business priorities and vision to teams.
• Line management and development of executive directors in program management.
• Lead cross-functional Operational CVRM leadership team.
• Assign capable CVRM Clinical Operations resources to meet project demands.
• Develop performance targets and metrics for operational delivery.
• Contribute to clinical site strategy and preferred site partnerships.
• Represent CVRM Clinical Operations in R&D Governance interactions with C-Suite.
• Sponsor non-drug strategy & organizational programs.
• Drive global standardization, continuous improvement, and efficiency gains.
• Lead and support change initiatives.
• Evaluate project performance and support issue resolution.
• Identify best practices with other VPs Clinical Operations.
• Support due diligence activities as needed.
• Develop, coach, mentor, motivate, and inspire individuals within the organization.
• Ensure compliance with ethics, policies, and standard procedures.
  

Essential Skills/Experience

• Advanced Degree
• Scientific background
• Extensive knowledge of clinical and pharmaceutical drug development process
• Experience working internationally: working with major markets/resolution of international issues
• Significant experience in Clinical Development and/or global operational study delivery
• Tried experience in project management
• Validated line management expertise
• Proven business acumen
• Professional excellence: Background of high professional achievement and willingness to encourage this in others
• Leads change with a positive approach to the challenges of change for self, team and the business. Sees change as an opportunity to improve performance and contribute to the business
• Demonstrated development of others, identifying and providing opportunities to improve the capabilities of other people
• Output/delivery focused
• Demonstrated ability to set and manage priorities, resources, performance targets and project initiatives in a global environment
• Cultural Awareness: Is aware of and sensitive to cultural differences and their impact on communication, expectations and performance.
• Teamwork and cross functional Collaboration: Is effective in leading and being a member of teams, both locally and internationally.
• Excellent communication skills
• Willingness to travel domestically and internationally
• Demonstrated ability to lead senior level staff
• Business planning skills: has knowledge/experience of planning processes used in managing drug projects
• Risk and crisis management experience
• Experience of leading successful teams from more than one national culture
• Manage cost center/department budget and project budget to threshold
  

Desirable Skills/Experience

• Preferentially having worked within CVRM (Cardiovascular, Renal, Metabolic) therapeutic area for at least 5 years and can demonstrate deep TA knowledge
• Creative and Innovative: Seeks to improve continuously where it counts, based on good awareness of external competitive practice, and creativity and initiative.
  

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility.
Join us in our unique and daring world.
At AstraZeneca, we are driven by our passion for science and our commitment to making a difference in patients' lives. Our innovative approach combines data, technology, and scientific breakthroughs to take on some of the world's most complex diseases. We champion an inclusive environment where curiosity thrives, empowering our teams to explore new possibilities without fear of failure. By collaborating with academia, biotechs, and industry leaders, we create swift impacts on disease treatment. Join us to push the boundaries of science and build a meaningful career.
Ready to make an impact? Apply now to join our dynamic team!
Date Posted
12-Aug-2025
Closing Date
27-Aug-2025
Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

Seniority level

• Seniority level

  Executive

Employment type

• Employment type

  Full-time

Job function

• Job function

  Research, Analyst, and Information Technology

• Industries

  Pharmaceutical Manufacturing

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