The Chan Zuckerberg Initiative was founded by Priscilla Chan and Mark Zuckerberg in 2015 to help solve some of society’s toughest challenges — from eradicating disease and improving education to addressing the needs of our local communities. Our mission is to build a more inclusive, just, and healthy future for everyone.
The Team
CZI supports the science and technology that will make it possible to help scientists cure, prevent, or manage all diseases by the end of this century. While this may seem like an audacious goal, in the last 100 years, biomedical science has made tremendous strides in understanding biological systems, advancing human health, and treating disease.
Achieving our mission will only be possible if scientists are able to better understand human biology. To that end, we have identified four grand challenges that will unlock the mysteries of the cell and how cells interact within systems — paving the way for new discoveries that will change medicine in the decades that follow:
- Building an AI-based virtual cell model to predict and understand cellular behavior
- Developing state-of-the-art imaging systems to observe living cells in action
- Instrumenting tissues to better understand inflammation, a key driver of many diseases
- Engineering and harnessing the immune system for early detection, prevention, and treatment of disease
CZI’s work in science includes grantmaking programs, open-source software development, and close collaboration with the Chan Zuckerberg Biohub Network. The CZ Biohub Network includes the San Francisco, Chicago, and New York Biohubs as well as the Chan Zuckerberg Imaging Institute. CZI also collaborates with institutional partners like the Kempner Institute for the Study of Natural & Artificial Intelligence at Harvard University. Join us in accelerating science.
The Opportunity
We are seeking a Senior Product Manager with deep expertise at the intersection of artificial intelligence and biology. In this role, you will lead the development of innovative products that apply state-of-the-art AI to accelerate biological research.
As part of the Science Technology (SciTech) team, you will shape products that empower both computational and experimental researchers to use AI for in silico experimentation, hypothesis generation, data interpretation, and biological modeling. You will work across disciplines to identify high-impact opportunities where AI can meaningfully accelerate scientific progress, and translate them into impactful, scalable tools integrated within the CZI Virtual Cells Platform .
- Multi-modal workflows for users to run inference on models using their own data for key tasks like data annotation and comparing data to a reference (e.g. healthy vs disease).
- Tools that enable researchers to run and visualize in silico experiments using AI models, e.g. simulate how specific gene knockouts affect cell behavior in a virtual T-cell model.
- Visualization library for visualizing and interacting with complex, multi-dimensional biological imaging data.
- AI agents that assist experimental biologists in designing experiments by integrating prior datasets, model predictions, and literature insights.
What You'll Do
- Define and drive the product strategy for AI-powered tools and agents that accelerate cell biology research.
- Build AI-powered biological workflows that translate model outputs into usable insights for experimental and computational biologists.
- Collaborate with scientific partners to deeply understand research needs and translate them into AI-driven solutions, bridging the gap between cutting-edge AI research and its real-world application in biological discovery.
- Lead the development and deployment of workflows that leverage models developed by CZI and the scientific community to enable in silico experimentation.
- Work closely with biologists, ML researchers, engineering, and design to deliver products that are intuitive, impactful, and well-integrated into researchers’ workflows.
- Collate and translate the needs of the CZ Imaging research teams into a platform strategy.
- Continuously scout and evaluate emerging AI technologies (e.g., multi-modal models, agentic frameworks) and identify opportunities to integrate cutting-edge technologies.
What You'll Bring
- 12+ years of product management or related experience, including at least 3 years working on AI or machine learning-powered products.
- Strong background in AI/ML product development, with a track record of building products that bridge the gap between complex technology and domain-specific users, preferably in scientific or technical environments.
- Experience applying AI models and agentic workflows (e.g., LLM-based agents, multi-step reasoning systems) to life science research problems.
- Demonstrated ability to work collaboratively with interdisciplinary teams and external partners.
- Excellent communication skills, with the ability to translate complex scientific and technical concepts for diverse audiences.
- Passion for CZI’s mission and a desire to drive scientific progress through technology.
- (nice to have) Experience working with cutting-edge biological imaging technology.
Compensation
The Redwood City, CA base pay range for this role is $241,000-$362,000. New hires are typically hired into the lower portion of the range, enabling employee growth in the range over time. Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process.
Benefits for the Whole You
We’re thankful to have an incredible team behind our work. To honor their commitment, we offer a wide range of benefits to support the people who make all we do possible.
- CZI provides a generous employer match on employee 401(k) contributions to support planning for the future.
- Annual benefit for employees that can be used most meaningfully for them and their families, such as housing, student loan repayment, childcare, commuter costs, or other life needs.
- CZI Life of Service Gifts are awarded to employees to “live the mission” and support the causes closest to them.
- Paid time off to volunteer at an organization of your choice.
- Relocation support for employees who need assistance moving to the Bay Area
If you’re interested in a role but your previous experience doesn’t perfectly align with each qualification in the job description, we still encourage you to apply as you may be the perfect fit for this or another role.
Accepted file types: pdf, doc, docx, txt, rtf
Enter manually
Accepted file types: pdf, doc, docx, txt, rtf
LinkedIn Profile
This role is a hybrid (Open to Flex) role and will require you to be onsite 60% of the working month at our HQ in Redwood City, CA. Will you be able to commit to this? * Select...
Are you currently eligible to work in the United States of America? * Select...
Do you now or in the future require visa sponsorship to continue working in the United States? * Select...
How did you hear about this job? * Select...
If 'Other', please specify how you heard about this job:
Have we met you at one of our events? If so, which one(s)? *
CZI-Sponsored Meetups
CZI-Sponsored Conferences
University Events / Career Fairs
None
Would you like to be invited to our recruiting events and receive information about what is happening at CZI? You’ll have the option to opt out at any time. * Select...
In the last 12 months, have you applied to any organization(s) within the Chan Zuckerberg Science ecosystem? * Select...
We have many exciting career opportunities available, and as part of our collaborative approach, we work with our hiring teams across our wider network to identify talent for our openings. Please opt-in or opt-out here if you would like us to share your profile for other opportunities. * Select...
Reasonable Accommodation and Data Privacy Notice. * Select...
Reasonable Accommodation Notice
CZI provides (and state and federal law requires) reasonable accommodations to qualified individuals with disabilities. Please tell us if you require a reasonable accommodation to apply for a job or to perform your job (reach out to your recruiter or ). Examples of reasonable accommodation include making a change to the application process or work procedures, providing documents in an alternate format, using a sign language interpreter, or using specialized equipment.
For government reporting purposes, we ask candidates to respond to the below self-identification survey.Completion of the form is entirely voluntary. Whatever your decision, it will not be considered in the hiringprocess or thereafter. Any information that you do provide will be recorded and maintained in aconfidential file.
As set forth in Chan Zuckerberg Initiative’s Equal Employment Opportunity policy,we do not discriminate on the basis of any protected group status under any applicable law.
If you believe you belong to any of the categories of protected veterans listed below, please indicate by making the appropriate selection.As a government contractor subject to the Vietnam Era Veterans Readjustment Assistance Act (VEVRAA), we request this information in order to measurethe effectiveness of the outreach and positive recruitment efforts we undertake pursuant to VEVRAA. Classification of protected categoriesis as follows:
A "disabled veteran" is one of the following: a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or a person who was discharged or released from active duty because of a service-connected disability.
A "recently separated veteran" means any veteran during the three-year period beginning on the date of such veteran's discharge or release from active duty in the U.S. military, ground, naval, or air service.
An "active duty wartime or campaign badge veteran" means a veteran who served on active duty in the U.S. military, ground, naval or air service during a war, or in a campaign or expedition for which a campaign badge has been authorized under the laws administered by the Department of Defense.
An "Armed forces service medal veteran" means a veteran who, while serving on active duty in the U.S. military, ground, naval or air service, participated in a United States military operation for which an Armed Forces service medal was awarded pursuant to Executive Order 12985.
Select...
Voluntary Self-Identification of Disability
Form CC-305
Page 1 of 1
OMB Control Number 1250-0005
Expires 04/30/2026
Voluntary Self-Identification of Disability
Form CC-305 Page 1 of 1 OMB Control Number 1250-0005 Expires 04/30/2026Why are you being asked to complete this form?
We are a federal contractor or subcontractor. The law requires us to provide equal employment opportunity to qualified people with disabilities. We have a goal of having at least 7% of our workers as people with disabilities. The law says we must measure our progress towards this goal. To do this, we must ask applicants and employees if they have a disability or have ever had one. People can become disabled, so we need to ask this question at least every five years.
Completing this form is voluntary, and we hope that you will choose to do so. Your answer is confidential. No one who makes hiring decisions will see it. Your decision to complete the form and your answer will not harm you in any way. If you want to learn more about the law or this form, visit the U.S. Department of Labor’s Office of Federal Contract Compliance Programs (OFCCP) website at .
How do you know if you have a disability?A disability is a condition that substantially limits one or more of your “major life activities.” If you have or have ever had such a condition, you are a person with a disability. Disabilities include, but are not limited to:
- Alcohol or other substance use disorder (not currently using drugs illegally)
- Autoimmune disorder, for example, lupus, fibromyalgia, rheumatoid arthritis, HIV/AIDS
- Blind or low vision
- Cancer (past or present)
- Cardiovascular or heart disease
- Celiac disease
- Cerebral palsy
- Deaf or serious difficulty hearing
- Diabetes
- Disfigurement, for example, disfigurement caused by burns, wounds, accidents, or congenital disorders
- Epilepsy or other seizure disorder
- Gastrointestinal disorders, for example, Crohn's Disease, irritable bowel syndrome
- Intellectual or developmental disability
- Mental health conditions, for example, depression, bipolar disorder, anxiety disorder, schizophrenia, PTSD
- Missing limbs or partially missing limbs
- Mobility impairment, benefiting from the use of a wheelchair, scooter, walker, leg brace(s) and/or other supports
- Nervous system condition, for example, migraine headaches, Parkinson’s disease, multiple sclerosis (MS)
- Neurodivergence, for example, attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder, dyslexia, dyspraxia, other learning disabilities
- Partial or complete paralysis (any cause)
- Pulmonary or respiratory conditions, for example, tuberculosis, asthma, emphysema
- Short stature (dwarfism)
- Traumatic brain injury
PUBLIC BURDEN STATEMENT: According to the Paperwork Reduction Act of 1995 no persons are required to respond to a collection of information unless such collection displays a valid OMB control number. This survey should take about 5 minutes to complete.
#J-18808-Ljbffr