Senior Bioinformatics Scientist – Transcriptomics

Senior Bioinformatics Scientist – Transcriptomics

Join to apply for the Senior Bioinformatics Scientist – Transcriptomics role at Somite AI

Senior Bioinformatics Scientist – Transcriptomics

Join to apply for the Senior Bioinformatics Scientist – Transcriptomics role at Somite AI

Senior Bioinformatician – Transcriptomics

Somite.ai

Senior Bioinformatician – Transcriptomics
About Somite.ai
Somite.ai is a venture-backed company transforming stem cell biology with AI. We recently raised over $47 million in a Series A funding round, bringing our total funding to about $60 million. Our mission is to transform regenerative medicine using our AI-driven DeltaStem platform. Just as LLMs revolutionized human language, we’re decoding the language of cells—how they communicate and decide their fate—using vast amounts of in-house generated data. Our AI models enable precise control over cell behavior, unlocking the potential to engineer therapies for diseases like diabetes, neurodegenerative diseases, and muscular dystrophies. Our platform, DeltaStem , accelerates therapy creation and continually improves through data-driven insights.
Founded by Dr. Micha Breakstone , a serial AI entrepreneur from MIT, and three Harvard Medical School professors, including the Chair of Genetics, Somite.ai is at the forefront of a new era in healthcare.
Location: Boston
Click The Following Links To Learn More About Somite:
The Following Link To Apply:
The Role:
We seek a skilled Bioinformatician to lead the design and execution of analysis pipelines for large-scale transcriptomic datasets. You’ll be responsible for preprocessing, quality control, and biological interpretation of sequencing data, contributing to the development of novel sequencing protocols and technologies in close collaboration with wet lab scientists, computational biologists and machine learning researchers to support Somite’s therapeutic programs.
This is a hands-on, data-centric role ideal for someone who thrives in a fast-paced, interdisciplinary environment and wants to help build transformative cell therapy technologies from the ground up.
Responsibilities:

• Build, maintain, and run robust, reproducible pipelines for single-cell and bulk RNA-seq data (QC, alignment, quantification, normalization, clustering, annotation, etc.).
• Apply standard and advanced analyses using tools like Scanpy, Seurat, and R/Bioconductor packages.
• Process and interpret data from state-of-the-art single-cell transcriptomic and multiomic platforms, alongside new in-house protocols being developed to enable innovative microbiological sequencing workflows.
• Collaborate with wet lab scientists to support experimental design and data interpretation.
• Mentor and foster collaboration and knowledge sharing across disciplines.
• Help design and validate cutting-edge protocols for novel transcriptomic technologies, integrating new experimental modalities with bioinformatics pipeline.
  

Qualifications:

• PhD in Bioinformatics, Genomics, Computational Biology, or a related field. Equivalent industry experience is also welcome.
• 3+ years of hands-on experience analyzing large-scale single-cell or bulk transcriptomic datasets.
• Proficiency with common genomics tools: SAMtools, STAR/STARsolo, Bowtie, Tophat, HTSeq, Clustal, bash scripting, etc.
• Strong command of Scanpy or Seurat
• Demonstrated fluency in Nextflow/Snakemake and workflow reproducibility principles.
• Strong R and/or Python programming skills.
  

Excellent organizational and documentation habits.
Preferred Qualifications:

• Experience working in a quantitative lab or with biotech/pharma pipelines.
• Experience working in a fast-paced startup or interdisciplinary team.
• The opportunity to contribute to platform technologies with real-world therapeutic impact.
• Experience working at the interface of technology development and data analysis, particularly involving novel molecular biology or sequencing techniques.
  

What We Offer

• A mission-driven team reshaping healthcare through innovation in AI and cellular engineering.
• The opportunity to contribute to platform technologies with real-world therapeutic impact.
• Competitive compensation and equity in a high-growth company.
• Flexible work arrangements, generous benefits, and a collaborative environment.
  

Somite.ai ’s Core Values:

• We show up – fully accountable, all-in, doing whatever it takes
• We act with urgency – swift, decisive, proactive
• We support one another – collaborative, helpful, empathetic
  

Click The Following Link To Apply:
candidates who demonstrate outstanding capabilities and potential will be considered, even if they do not meet every qualification listed.
Join and help us unlock the full potential of AI for the benefit of human health .

Seniority level

• Seniority level

  Mid-Senior level

Employment type

• Employment type

  Full-time

Job function

• Job function

  Research, Analyst, and Information Technology

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