Chan Zuckerberg
Senior Staff Data Scientist, Imaging, Data, Science (Opens in new window)
Chan Zuckerberg, Redwood City, California, United States, 94061
Senior Staff Data Scientist, Imaging, Data, Science
Redwood City, CA (Open to Hybrid) The Chan Zuckerberg Initiative was founded by Priscilla Chan and Mark Zuckerberg in 2015 to help solve some of society’s toughest challenges — from eradicating disease and improving education to addressing the needs of our local communities. Our mission is to build a more inclusive, just, and healthy future for everyone. The Team
CZI and its Biohub Network supports the science and technology that will make it possible to help scientists cure, prevent, or manage all diseases by the end of this century. While this may seem like an audacious goal, in the last 100 years, biomedical science has made tremendous strides in understanding biological systems, advancing human health, and treating disease. Achieving our mission will only be possible if scientists are able to better understand human biology. To that end, we have identified four grand challenges that will unlock the mysteries of the cell and how cells interact within systems — paving the way for new discoveries that will change medicine in the decades that follow: Building an AI-based virtual cell model to predict and understand cellular behavior Developing novel imaging technologies to map, measure and model complex biological systems Creating new tools for sensing and directly measuring inflammation within tissues in real time.tissues to better understand inflammation, a key driver of many diseases Harnessing the immune system for early detection, prevention, and treatment of disease Our work in science is focused on doing fundamental research to better understand human biology and building the tools and technology that move science forward to prevent disease and get to cures faster. Join us in accelerating science. The Opportunity
At CZI, we are generating unprecedented scientific datasets that drive biological modeling innovation: Billions of standardized cells of single-cell transcriptomic data, with a focus on measuring genetic and environmental perturbations 10s of thousands of donor-matched DNA & RNA samples PB-scale static and dynamic imaging datasets TB-scale mass spectrometry datasets Diverse, large multi-modal biological datasets that enable biological bridges across measurement types and facilitate multi-modal model training to define how cells act. After model training, we make all data products available through public resources like CELLxGENE Discover and the CryoET Portal, used by tens of thousands of scientists monthly to advance understanding of genetic variants, disease risk, drug toxicities, and therapeutic discovery. As a Senior Staff Data Scientist, you'll lead the creation of groundbreaking imaging datasets that decode cellular function at the molecular level, describe development, and predict responses to genetic or environmental changes. Working at the intersection of data science, biology, and AI, you'll define data needs, format standards, analysis approaches, quality metrics, and our technical strategy, creating systems to ingest, transform, and validate and deploy data products. Success for this role means delivering high-quality, usable datasets that directly address modeling challenges and accelerate scientific progress. Join us in building the data foundation that will transform our understanding of human biology and move us along the path to curing, preventing, and managing all disease. What You'll Do
Define the technical strategy for a robust imaging data ecosystem and build data ingestion pipelines, define data formats, write validation tools, QC metrics, and analysis pipelines. Collaborate with ML engineers, AI Researchers, and Data Engineers to iteratively evaluate, refine and grow datasets to maximize model performance. Discover and define new data generation opportunities, and manage the delivery of those data products to our AI team. Collaborate with engineers, product managers, UX designers, and other data scientists to publish valuable datasets as part of CZI's open data ecosystem. What You'll Bring
10+ years of experience with large scale biological imaging data. Demonstrated delivery of multiple large biological data products. Experience with big data: extraction, transport, loading, databases, standardization, validation, QC, and analysis. Strong fundamentals in statistical reasoning and machine learning. Experience with biological data analysis and QC best practices Excellent written and verbal communication skills. Enthusiasm to ramp up on technologies and learn new domains. Experience working in a multidisciplinary environment (engineering, product, AI Research). Compensation
The Redwood City, CA base pay range for a new hire in this role is $241,000 - $331,100. New hires are typically hired into the lower portion of the range, enabling employee growth in the range over time. Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process. Better Together
As we grow, we’re excited to strengthen in-person connections and cultivate a collaborative, team-oriented environment. This role is a hybrid position requiring you to be onsite for at least 60% of the working month, approximately 3 days a week, with specific in-office days determined by the team’s manager. The exact schedule will be at the hiring manager's discretion and communicated during the interview process. Benefits for the Whole You
We’re thankful to have an incredible team behind our work. To honor their commitment, we offer a wide range of benefits to support the people who make all we do possible. CZI provides a generous employer match on employee 401(k) contributions to support planning for the future. Annual benefit for employees that can be used most meaningfully for them and their families, such as housing, student loan repayment, childcare, commuter costs, or other life needs. CZI Life of Service Gifts are awarded to employees to “live the mission” and support the causes closest to them. Paid time off to volunteer at an organization of your choice. Relocation support for employees who need assistance moving to the Bay Area If you’re interested in a role but your previous experience doesn’t perfectly align with each qualification in the job description, we still encourage you to apply as you may be the perfect fit for this or another role. Accepted file types: pdf, doc, docx, txt, rtf Enter manually Accepted file types: pdf, doc, docx, txt, rtf LinkedIn Profile This role is a hybrid role and will require you to be onsite approximately 3 days a week at our HQ in Redwood City, CA. Will you be able to commit to this? Select... Are you currently eligible to work in the United States of America? * Select... Do you now or in the future require visa sponsorship to continue working in the United States? * Select... How did you hear about this job? * Select... If 'Other', please specify how you heard about this job: Have we met you at one of our events? If so, which one(s)? * CZI-Sponsored Meetups CZI-Sponsored Conferences University Events / Career Fairs None Would you like to be invited to our recruiting events and receive information about what is happening at CZI? You’ll have the option to opt out at any time. * Select... In the last 12 months, have you applied to any organization(s) within the Chan Zuckerberg Science ecosystem? * Select... We have many exciting career opportunities available, and as part of our collaborative approach, we work with our hiring teams across our wider network to identify talent for our openings. Please opt-in or opt-out here if you would like us to share your profile for other opportunities. * Select... Reasonable Accommodation and Data Privacy Notice. * Select... Reasonable Accommodation Notice CZI provides (and state and federal law requires) reasonable accommodations to qualified individuals with disabilities. Please tell us if you require a reasonable accommodation to apply for a job or to perform your job (reach out to your recruiter or accommodations@chanzuckerberg.com ). Examples of reasonable accommodation include making a change to the application process or work procedures, providing documents in an alternate format, using a sign language interpreter, or using specialized equipment. For reporting purposes, we ask candidates to respond to the below self-identification survey. Completion of the form is entirely voluntary. Whatever your decision, it will not be considered in the hiring process or thereafter. Any information that you do provide will be recorded and maintained in a confidential file. As set forth in Chan Zuckerberg Initiative’s Equal Employment Opportunity policy, we do not discriminate on the basis of any protected group status under any applicable law. If you believe you belong to any of the categories of protected veterans listed below, please indicate by making the appropriate selection. Classification of protected categories is as follows: A "disabled veteran" is one of the following: a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or a person who was discharged or released from active duty because of a service-connected disability. A "recently separated veteran" means any veteran during the three-year period beginning on the date of such veteran's discharge or release from active duty in the U.S. military, ground, naval, or air service. An "active duty wartime or campaign badge veteran" means a veteran who served on active duty in the U.S. military, ground, naval or air service during a war, or in a campaign or expedition for which a campaign badge has been authorized under the laws administered by the Department of Defense. An "Armed forces service medal veteran" means a veteran who, while serving on active duty in the U.S. military, ground, naval or air service, participated in a United States military operation for which an Armed Forces service medal was awarded pursuant to Executive Order 12985.
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Redwood City, CA (Open to Hybrid) The Chan Zuckerberg Initiative was founded by Priscilla Chan and Mark Zuckerberg in 2015 to help solve some of society’s toughest challenges — from eradicating disease and improving education to addressing the needs of our local communities. Our mission is to build a more inclusive, just, and healthy future for everyone. The Team
CZI and its Biohub Network supports the science and technology that will make it possible to help scientists cure, prevent, or manage all diseases by the end of this century. While this may seem like an audacious goal, in the last 100 years, biomedical science has made tremendous strides in understanding biological systems, advancing human health, and treating disease. Achieving our mission will only be possible if scientists are able to better understand human biology. To that end, we have identified four grand challenges that will unlock the mysteries of the cell and how cells interact within systems — paving the way for new discoveries that will change medicine in the decades that follow: Building an AI-based virtual cell model to predict and understand cellular behavior Developing novel imaging technologies to map, measure and model complex biological systems Creating new tools for sensing and directly measuring inflammation within tissues in real time.tissues to better understand inflammation, a key driver of many diseases Harnessing the immune system for early detection, prevention, and treatment of disease Our work in science is focused on doing fundamental research to better understand human biology and building the tools and technology that move science forward to prevent disease and get to cures faster. Join us in accelerating science. The Opportunity
At CZI, we are generating unprecedented scientific datasets that drive biological modeling innovation: Billions of standardized cells of single-cell transcriptomic data, with a focus on measuring genetic and environmental perturbations 10s of thousands of donor-matched DNA & RNA samples PB-scale static and dynamic imaging datasets TB-scale mass spectrometry datasets Diverse, large multi-modal biological datasets that enable biological bridges across measurement types and facilitate multi-modal model training to define how cells act. After model training, we make all data products available through public resources like CELLxGENE Discover and the CryoET Portal, used by tens of thousands of scientists monthly to advance understanding of genetic variants, disease risk, drug toxicities, and therapeutic discovery. As a Senior Staff Data Scientist, you'll lead the creation of groundbreaking imaging datasets that decode cellular function at the molecular level, describe development, and predict responses to genetic or environmental changes. Working at the intersection of data science, biology, and AI, you'll define data needs, format standards, analysis approaches, quality metrics, and our technical strategy, creating systems to ingest, transform, and validate and deploy data products. Success for this role means delivering high-quality, usable datasets that directly address modeling challenges and accelerate scientific progress. Join us in building the data foundation that will transform our understanding of human biology and move us along the path to curing, preventing, and managing all disease. What You'll Do
Define the technical strategy for a robust imaging data ecosystem and build data ingestion pipelines, define data formats, write validation tools, QC metrics, and analysis pipelines. Collaborate with ML engineers, AI Researchers, and Data Engineers to iteratively evaluate, refine and grow datasets to maximize model performance. Discover and define new data generation opportunities, and manage the delivery of those data products to our AI team. Collaborate with engineers, product managers, UX designers, and other data scientists to publish valuable datasets as part of CZI's open data ecosystem. What You'll Bring
10+ years of experience with large scale biological imaging data. Demonstrated delivery of multiple large biological data products. Experience with big data: extraction, transport, loading, databases, standardization, validation, QC, and analysis. Strong fundamentals in statistical reasoning and machine learning. Experience with biological data analysis and QC best practices Excellent written and verbal communication skills. Enthusiasm to ramp up on technologies and learn new domains. Experience working in a multidisciplinary environment (engineering, product, AI Research). Compensation
The Redwood City, CA base pay range for a new hire in this role is $241,000 - $331,100. New hires are typically hired into the lower portion of the range, enabling employee growth in the range over time. Actual placement in range is based on job-related skills and experience, as evaluated throughout the interview process. Better Together
As we grow, we’re excited to strengthen in-person connections and cultivate a collaborative, team-oriented environment. This role is a hybrid position requiring you to be onsite for at least 60% of the working month, approximately 3 days a week, with specific in-office days determined by the team’s manager. The exact schedule will be at the hiring manager's discretion and communicated during the interview process. Benefits for the Whole You
We’re thankful to have an incredible team behind our work. To honor their commitment, we offer a wide range of benefits to support the people who make all we do possible. CZI provides a generous employer match on employee 401(k) contributions to support planning for the future. Annual benefit for employees that can be used most meaningfully for them and their families, such as housing, student loan repayment, childcare, commuter costs, or other life needs. CZI Life of Service Gifts are awarded to employees to “live the mission” and support the causes closest to them. Paid time off to volunteer at an organization of your choice. Relocation support for employees who need assistance moving to the Bay Area If you’re interested in a role but your previous experience doesn’t perfectly align with each qualification in the job description, we still encourage you to apply as you may be the perfect fit for this or another role. Accepted file types: pdf, doc, docx, txt, rtf Enter manually Accepted file types: pdf, doc, docx, txt, rtf LinkedIn Profile This role is a hybrid role and will require you to be onsite approximately 3 days a week at our HQ in Redwood City, CA. Will you be able to commit to this? Select... Are you currently eligible to work in the United States of America? * Select... Do you now or in the future require visa sponsorship to continue working in the United States? * Select... How did you hear about this job? * Select... If 'Other', please specify how you heard about this job: Have we met you at one of our events? If so, which one(s)? * CZI-Sponsored Meetups CZI-Sponsored Conferences University Events / Career Fairs None Would you like to be invited to our recruiting events and receive information about what is happening at CZI? You’ll have the option to opt out at any time. * Select... In the last 12 months, have you applied to any organization(s) within the Chan Zuckerberg Science ecosystem? * Select... We have many exciting career opportunities available, and as part of our collaborative approach, we work with our hiring teams across our wider network to identify talent for our openings. Please opt-in or opt-out here if you would like us to share your profile for other opportunities. * Select... Reasonable Accommodation and Data Privacy Notice. * Select... Reasonable Accommodation Notice CZI provides (and state and federal law requires) reasonable accommodations to qualified individuals with disabilities. Please tell us if you require a reasonable accommodation to apply for a job or to perform your job (reach out to your recruiter or accommodations@chanzuckerberg.com ). Examples of reasonable accommodation include making a change to the application process or work procedures, providing documents in an alternate format, using a sign language interpreter, or using specialized equipment. For reporting purposes, we ask candidates to respond to the below self-identification survey. Completion of the form is entirely voluntary. Whatever your decision, it will not be considered in the hiring process or thereafter. Any information that you do provide will be recorded and maintained in a confidential file. As set forth in Chan Zuckerberg Initiative’s Equal Employment Opportunity policy, we do not discriminate on the basis of any protected group status under any applicable law. If you believe you belong to any of the categories of protected veterans listed below, please indicate by making the appropriate selection. Classification of protected categories is as follows: A "disabled veteran" is one of the following: a veteran of the U.S. military, ground, naval or air service who is entitled to compensation (or who but for the receipt of military retired pay would be entitled to compensation) under laws administered by the Secretary of Veterans Affairs; or a person who was discharged or released from active duty because of a service-connected disability. A "recently separated veteran" means any veteran during the three-year period beginning on the date of such veteran's discharge or release from active duty in the U.S. military, ground, naval, or air service. An "active duty wartime or campaign badge veteran" means a veteran who served on active duty in the U.S. military, ground, naval or air service during a war, or in a campaign or expedition for which a campaign badge has been authorized under the laws administered by the Department of Defense. An "Armed forces service medal veteran" means a veteran who, while serving on active duty in the U.S. military, ground, naval or air service, participated in a United States military operation for which an Armed Forces service medal was awarded pursuant to Executive Order 12985.
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