Roswell Park Comprehensive Cancer Center
Senior Research Specialist - Bioinformatics Programmer
Roswell Park Comprehensive Cancer Center, Buffalo, New York, United States, 14266
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Title
Senior Research Specialist - Bioinformatics Programmer
Job Type
Regular
Company
Health Research, Inc. (HRI) Roswell Park Division
Department
Molecular & Cellular Biology
Time Type
Full time
Weekly Hours
40
Fte
1
Shift
First Shift (United States of America)
Summary
The Koren lab at the Department of Molecular and Cellular Biology at Roswell Park Comprehensive Cancer Center uses genomic and computational approaches to study DNA replication timing and mutagenesis. The lab focuses on human populations and on comprehensive pan-cancer analyses, integrating additional large-scale genomics and epigenomics datasets. We develop methods for inferring DNA replication dynamics from whole genome sequence data, analyze the inter-relations between replication timing and epigenomic regulation, and understand the factors that affect mutation rates and patterns across normal and cancer genomes. More information is available at www.thekorenlab.org.
The Bioinformatics Programmer will be involved in analyzing existing data related to population-level variation in DNA replication timing among humans, developing new pipelines for the inference of DNA replication timing along with DNA copy number from cancer genomes, applying those pipelines to thousands of cancer samples, and performing downstream cancer genomics analyses including mutation patterns. He/she will have experience in one or more of the following: human genetics/genomics, cancer genetics/genomics, epigenetics, genome stability, genotyping and mutation calling and analysis, genome-wide association studies and/or quantitative trait loci mapping, population genetics, or similar disciplines. Expert knowledge in one or more programming environments such as R, Python, Matlab or similar, and experience analyzing large-scale datasets using computer cluster or cloud platforms. Previous publications in peer-reviewed journals are required.
The lab offers flexible working schedules, ability to pursue cutting-edge research both independently and collaboratively, and a welcoming and supportive environment.
Salary range for the Senior Research Specialist is $73, 627 - $90,955 annually which includes a comprehensive benefits package. The listed pay range reflects the range of potential compensation for this role. The actual offer may vary based on qualifications, skills, and experience
Qualifications
Required Education and Experience
PhD and the equivalent of two (2) years of full-time professional research experience in a laboratory, clinical or scientific research environment; or Master’s degree and the equivalent of four (4) years of full-time professional research experience in a laboratory, clinical or scientific research environment; or Bachelor’s degree and the equivalent of six (6) years of full-time professional research experience in a laboratory, clinical or scientific research environment
Note
Required degrees must have been granted by an accredited school, college or university or one recognized by Roswell Park Comprehensive Cancer Center as following acceptable educational practices.
Preferred Qualifications
PhD or equivalent education plus experience in bioinformatics, genomics, genetics, computer science or related field Experience in human and/or cancer genomics and bioinformatics Experience with higher-level programming with relevant languages or platforms such as Matlab, R, python or similar Experience analyzing large-scale databases spanning thousands of samples in a computer cluster and/or cloud computing setting Ability to keep records, follow procedures, communicate effectively, and collaborate with others
Equal Employment Opportunity Statement
Roswell Park Cancer Institute Corporation (RPCIC) and Health Research Inc. (HRI) Roswell Park Division believe that all persons are entitled to equal employment opportunities, and we do not discriminate against our employees, applicants or job seekers because of their race, color, religion, sex, sexual orientation, gender identity or expression, national origin, creed, age, disability, pregnancy-related condition, military or veteran status, marital or familial status, domestic violence victim status, citizenship status, genetic information, individual’s relationship or association with a member of a protected category or any other protected group status as defined by law.
Affirmative Action/Equal Opportunity Employer/Qualified Individuals with Disabilities/Qualified Protected Veterans
Reasonable Accommodation Request
RPCIC and HRI are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the employment process, please email HR-PayAndBenefits@RoswellPark.org and let us know the nature of your request and your contact information.
Our Core Values
RPCIC and HRI are committed to providing an environment where patients, families, employees and community are treated with courtesy and respect. We support an inclusive environment that nurtures the talents, skills and abilities of each individual to embody and reflect our core values: Innovation, Integrity, Teamwork, Commitment, Compassion and Respect.
Grant Funding
This is a grant-funded position. Compliance with funding requirements such as time and effort reporting, grant deliverables, and contract deliverables is required.
E-Verify Employer
Health Research Inc. (HRI) Roswell Park Division participates in the E-Verify program. Seniority level
Seniority level Mid-Senior level Employment type
Employment type Full-time Job function
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Senior Research Specialist - Bioinformatics Programmer
Job Type
Regular
Company
Health Research, Inc. (HRI) Roswell Park Division
Department
Molecular & Cellular Biology
Time Type
Full time
Weekly Hours
40
Fte
1
Shift
First Shift (United States of America)
Summary
The Koren lab at the Department of Molecular and Cellular Biology at Roswell Park Comprehensive Cancer Center uses genomic and computational approaches to study DNA replication timing and mutagenesis. The lab focuses on human populations and on comprehensive pan-cancer analyses, integrating additional large-scale genomics and epigenomics datasets. We develop methods for inferring DNA replication dynamics from whole genome sequence data, analyze the inter-relations between replication timing and epigenomic regulation, and understand the factors that affect mutation rates and patterns across normal and cancer genomes. More information is available at www.thekorenlab.org.
The Bioinformatics Programmer will be involved in analyzing existing data related to population-level variation in DNA replication timing among humans, developing new pipelines for the inference of DNA replication timing along with DNA copy number from cancer genomes, applying those pipelines to thousands of cancer samples, and performing downstream cancer genomics analyses including mutation patterns. He/she will have experience in one or more of the following: human genetics/genomics, cancer genetics/genomics, epigenetics, genome stability, genotyping and mutation calling and analysis, genome-wide association studies and/or quantitative trait loci mapping, population genetics, or similar disciplines. Expert knowledge in one or more programming environments such as R, Python, Matlab or similar, and experience analyzing large-scale datasets using computer cluster or cloud platforms. Previous publications in peer-reviewed journals are required.
The lab offers flexible working schedules, ability to pursue cutting-edge research both independently and collaboratively, and a welcoming and supportive environment.
Salary range for the Senior Research Specialist is $73, 627 - $90,955 annually which includes a comprehensive benefits package. The listed pay range reflects the range of potential compensation for this role. The actual offer may vary based on qualifications, skills, and experience
Qualifications
Required Education and Experience
PhD and the equivalent of two (2) years of full-time professional research experience in a laboratory, clinical or scientific research environment; or Master’s degree and the equivalent of four (4) years of full-time professional research experience in a laboratory, clinical or scientific research environment; or Bachelor’s degree and the equivalent of six (6) years of full-time professional research experience in a laboratory, clinical or scientific research environment
Note
Required degrees must have been granted by an accredited school, college or university or one recognized by Roswell Park Comprehensive Cancer Center as following acceptable educational practices.
Preferred Qualifications
PhD or equivalent education plus experience in bioinformatics, genomics, genetics, computer science or related field Experience in human and/or cancer genomics and bioinformatics Experience with higher-level programming with relevant languages or platforms such as Matlab, R, python or similar Experience analyzing large-scale databases spanning thousands of samples in a computer cluster and/or cloud computing setting Ability to keep records, follow procedures, communicate effectively, and collaborate with others
Equal Employment Opportunity Statement
Roswell Park Cancer Institute Corporation (RPCIC) and Health Research Inc. (HRI) Roswell Park Division believe that all persons are entitled to equal employment opportunities, and we do not discriminate against our employees, applicants or job seekers because of their race, color, religion, sex, sexual orientation, gender identity or expression, national origin, creed, age, disability, pregnancy-related condition, military or veteran status, marital or familial status, domestic violence victim status, citizenship status, genetic information, individual’s relationship or association with a member of a protected category or any other protected group status as defined by law.
Affirmative Action/Equal Opportunity Employer/Qualified Individuals with Disabilities/Qualified Protected Veterans
Reasonable Accommodation Request
RPCIC and HRI are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the employment process, please email HR-PayAndBenefits@RoswellPark.org and let us know the nature of your request and your contact information.
Our Core Values
RPCIC and HRI are committed to providing an environment where patients, families, employees and community are treated with courtesy and respect. We support an inclusive environment that nurtures the talents, skills and abilities of each individual to embody and reflect our core values: Innovation, Integrity, Teamwork, Commitment, Compassion and Respect.
Grant Funding
This is a grant-funded position. Compliance with funding requirements such as time and effort reporting, grant deliverables, and contract deliverables is required.
E-Verify Employer
Health Research Inc. (HRI) Roswell Park Division participates in the E-Verify program. Seniority level
Seniority level Mid-Senior level Employment type
Employment type Full-time Job function
Job function Research, Analyst, and Information Technology Industries Hospitals and Health Care Referrals increase your chances of interviewing at Roswell Park Comprehensive Cancer Center by 2x Get notified about new Senior Researcher jobs in
Buffalo, NY . Buffalo, NY $39,900.00-$185,000.00 2 weeks ago Grand Island, NY $83,300.00-$116,000.00 1 day ago Cell Biology Scientist II, BioProduction R&D (Grand Island, NY)
Grand Island, NY $70,000.00-$88,000.00 6 days ago Cell Biology Scientist II, BioProduction R&D (Grand Island, NY)
Buffalo, NY $70,000.00-$88,000.00 6 days ago Grand Island, NY $83,300.00-$125,000.00 6 days ago Buffalo, NY $65,000.00-$85,000.00 1 day ago Lancaster, NY $65,000.00-$80,000.00 1 month ago Scientist I, Cell Biology (Grand Island, NY)
Buffalo, NY $54,000.00-$65,000.00 6 days ago Sr Research Scientist – Inhaled Drug Delivery/MDI
Buffalo, NY $137,000.00-$144,000.00 2 weeks ago Scientist I, Cell Biology (Grand Island, NY)
Grand Island, NY $54,000.00-$65,000.00 6 days ago We’re unlocking community knowledge in a new way. Experts add insights directly into each article, started with the help of AI.
#J-18808-Ljbffr