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Summit Therapeutics, Inc.

Associate Director, Facility Management

Summit Therapeutics, Inc., Menlo Park

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About Summit
Ivonescimab, known as SMT112, is a novel, potential first-in-class investigational bispecific antibody combining the effects of immunotherapy via a blockade of PD-1 with the anti-angiogenesis effects associated with blocking VEGF into a single molecule. Ivonescimab displays unique cooperative binding to each of its intended targets with multifold higher affinity when in the presence of both PD-1 and VEGF.

ASSOCIATE DIRECTOR, FACILITY MANAGMENT
Location: Palo Alto, CA
About Summit
Ivonescimab, known as SMT112, is a novel, potential first-in-class investigational bispecific antibody combining the effects of immunotherapy via a blockade of PD-1 with the anti-angiogenesis effects associated with blocking VEGF into a single molecule. Ivonescimab displays unique cooperative binding to each of its intended targets with multifold higher affinity when in the presence of both PD-1 and VEGF.
Summit has begun its clinical development of ivonescimab in non-small cell lung cancer (NSCLC), with three active Phase III trials:

  • HARMONi is a Phase III clinical trial which intends to evaluate ivonescimab combined with chemotherapy compared to placebo plus chemotherapy in patients with EGFR-mutated, locally advanced or metastatic non-squamous NSCLC who have progressed after treatment with a 3rd generation EGFR TKI (e.g., osimertinib).
  • HARMONi-3 is a Phase III clinical trial which is designed to evaluate ivonescimab combined with chemotherapy compared to pembrolizumab combined with chemotherapy in patients with first-line metastatic NSCLC.
  • HARMONi-7 is a Phase III clinical trial which is intended to evaluate ivonescimab monotherapy compared to pembrolizumab monotherapy in patients with first-line metastatic NSCLC whose tumors have high PD-L1 expression.
Ivonescimab is an investigational therapy that is not approved by any regulatory authority in Summit’s license territories, including the United States and Europe. Ivonescimab was approved for marketing authorization in China in May 2024. Ivonescimab was granted Fast Track designation by the US Food & Drug Administration (FDA) for the HARMONi clinical trial setting.
Overview Of Role
The Associate Director, Facilities Management will oversee operations for our U.S. and European office locations. This role ensures facilities are secure, compliant, and cost-efficient, while optimizing space and enhancing the employee experience. The leader will manage vendor partnerships, regulatory compliance, and physical security programs across regions. Partnering with senior leadership, they will drive a scalable global facilities strategy aligned with business growth. This position requires a hands-on operator with strong management and leadership skills—capable of executing day-to-day operations while also shaping and delivering long-term facilities strategies at the global level.
Role And Responsibilities
  • Operations & Space Management – Lead day-to-day operations across office locations, ensuring optimal use of space and alignment with organizational growth.
  • Physical Security & Safety – Implement global security standards, workplace safety programs, emergency response protocols, and business continuity measures.
  • Regulatory Compliance – Ensure adherence to U.S. and European building codes, healthcare regulations, EHS standards, and all required audits.
  • Vendor & Service Management – Oversee vendor contracts, SLAs, and performance across maintenance, security, janitorial, and workplace services.
  • Employee Experience – Deliver facilities services that enhance employee productivity, engagement, and well-being.
  • Technology & Efficiency – Implement IT-enabled solutions for facility efficiency (workspace management platforms, desk booking, asset tracking, space optimization tools, access control systems).
  • All other duties as assigned
Experience, Education And Specialized Knowledge And Skills
  • Bachelor’s degree in Facilities Management, Engineering, Business, or related field.
  • Minimum of 7+ years of experience in facilities management, with oversight of multi-office/global operations.
  • Strong expertise in physical security, vendor management, and regulatory compliance (OSHA, ADA, HSE, healthcare standards).
  • Proven success in managing budgets, negotiating contracts, and leading cross-functional initiatives.
  • Excellent leadership, problem-solving, and communication skills with the ability to influence senior stakeholders.
  • Certified Healthcare Facility Manager (CHFM) is highly desirable.
  • Experience implementing IT-enabled solutions for facilities efficiency (automation, space booking, asset tracking).
The pay range for this role is $168,000-$180,000 annually. Actual compensation packages are based on several factors that are unique to each candidate, including but not limited to skill set, depth of experience, certifications, and specific work location. This may be different in other locations due to differences in the cost of labor. The total compensation package for this position may also include bonus, stock, benefits and/or other applicable variable compensation.
Summit does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact Summit’s Talent Acquisition team at to obtain prior written authorization before referring any candidates to Summit.

Seniority level

  • Seniority level

    Mid-Senior level

Employment type

  • Employment type

    Full-time

Job function

  • Job function

    Strategy/Planning and Information Technology

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