TransMedics
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Principal Systems Engineer
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TransMedics, Inc. 1 day ago Be among the first 25 applicants Join to apply for the
Principal Systems Engineer
role at
TransMedics, Inc. Get AI-powered advice on this job and more exclusive features. Job Description
POSITION SUMMARY
We are seeking a highly experienced and technically versatile Principal Systems Engineer with a strong foundation in electrical engineering, complemented by working knowledge of chemistry or biosensing principles. This senior-level role is critical to leading the integration of complicated electromechanical subsystems and biosensors into our organ preservation systems and acting as a strategic liaison with external development partners and internal cross-functional teams. As the Principal Systems Engineer, you will provide technical leadership, drive architecture decisions, and ensure system-level cohesion across electrical, fluidic, biochemical, and software interfaces. You will also mentor junior engineers, lead technical risk management efforts, and contribute to long-term product strategy.
Responsibilities
This position is responsible for, but not limited to, the following:
Act as lead technical liaison with sensor development firms and cross-functional stakeholders Provide senior-level guidance on systems architecture and design trade-offs Serve as technical owner and systems integrator for all subsystems and biosensors within our product ecosystem Interface with and manage external design and development firms, ensuring adherence to timelines, specifications, and quality standards Translate clinical and functional requirements into system-level architecture and testable specifications Lead design reviews, risk assessments, and integration planning across electrical, mechanical, software and fluidic, and biochemical subsystems Coordinate V&V (verification and validation) activities related to subsystem and sensor performance and system compatibility Ensure compliance with applicable regulatory standards (e.g., ISO 13485, IEC 60601, FDA guidance) Collaborate with internal R&D, software, clinical, and regulatory teams to advance product development milestones Perform other TransMedics tasks and duties as assigned/required.
Management Responsibilities
This position manages the following positions on a daily basis.
This position will not have management responsibilities.
PHYSICAL ATTRIBUTES
Office Environment Ability to lift 25 pounds
Minimum Qualifications
Bachelors degree in Electrical Engineering or equivalent technical field 8+ years of experience in medical device or diagnostics development, with increasing responsibility
Preferred Qualifications
Masters degree in either Electrical, Computer or Biomedical Engineering Proven experience in biosensor systems monitoring applications Demonstrated ability to oversee external development teams or OEM suppliers Familiarity with system architecture, signal processing, and device integration Experience with design control processes and medical product lifecycle development Working knowledge of biocompatibility, fluid dynamics, or clinical workflows is a plus Strong systems thinking across hardware, software, and biology Effective communicator and technical project coordinator Detail-oriented with a high sense of ownership Comfortable working in early-stage, cross-functional teams Adaptable and hands-on, with the ability to shift between technical depth and high-level coordination Experience managing or guiding cross-functional engineering teams Proven track record of technical leadership and systems integration in regulated medical products
Every Organ Wasted is a Life Not Saved.
TransMedics, Inc. is a commercial-stage medical technology company transforming organ transplant therapy for patients worldwide. Our mission is to help save more patients lives by increasing access to viable donor organs for those who are awaiting an organ transplant. To accomplish this mission, we partner closely with transplant stakeholders worldwide and help expand their access to healthy donor organs, while delivering the highest quality technology, service, clinical care and outcomes.
Driven by a passion for improving patient care, we make the impossible possible and keep our employees at the center of everything we do. Together, we strive to enhance the quality of life for transplant recipients and their families, fostering hope and healing in the journey toward better health.
Maximize your potential at TransMedics, Inc.
www.TransMedics.com
TransMedics is an equal opportunity employer and does not discriminate on the basis of race, color, religion, sex, national origin, marital status, age, disability or protected veteran status, or any other characteristic protected by law. We are committed to creating an inclusive environment for all employees.
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Principal Systems Engineer
role at
TransMedics, Inc. 1 day ago Be among the first 25 applicants Join to apply for the
Principal Systems Engineer
role at
TransMedics, Inc. Get AI-powered advice on this job and more exclusive features. Job Description
POSITION SUMMARY
We are seeking a highly experienced and technically versatile Principal Systems Engineer with a strong foundation in electrical engineering, complemented by working knowledge of chemistry or biosensing principles. This senior-level role is critical to leading the integration of complicated electromechanical subsystems and biosensors into our organ preservation systems and acting as a strategic liaison with external development partners and internal cross-functional teams. As the Principal Systems Engineer, you will provide technical leadership, drive architecture decisions, and ensure system-level cohesion across electrical, fluidic, biochemical, and software interfaces. You will also mentor junior engineers, lead technical risk management efforts, and contribute to long-term product strategy.
Responsibilities
This position is responsible for, but not limited to, the following:
Act as lead technical liaison with sensor development firms and cross-functional stakeholders Provide senior-level guidance on systems architecture and design trade-offs Serve as technical owner and systems integrator for all subsystems and biosensors within our product ecosystem Interface with and manage external design and development firms, ensuring adherence to timelines, specifications, and quality standards Translate clinical and functional requirements into system-level architecture and testable specifications Lead design reviews, risk assessments, and integration planning across electrical, mechanical, software and fluidic, and biochemical subsystems Coordinate V&V (verification and validation) activities related to subsystem and sensor performance and system compatibility Ensure compliance with applicable regulatory standards (e.g., ISO 13485, IEC 60601, FDA guidance) Collaborate with internal R&D, software, clinical, and regulatory teams to advance product development milestones Perform other TransMedics tasks and duties as assigned/required.
Management Responsibilities
This position manages the following positions on a daily basis.
This position will not have management responsibilities.
PHYSICAL ATTRIBUTES
Office Environment Ability to lift 25 pounds
Minimum Qualifications
Bachelors degree in Electrical Engineering or equivalent technical field 8+ years of experience in medical device or diagnostics development, with increasing responsibility
Preferred Qualifications
Masters degree in either Electrical, Computer or Biomedical Engineering Proven experience in biosensor systems monitoring applications Demonstrated ability to oversee external development teams or OEM suppliers Familiarity with system architecture, signal processing, and device integration Experience with design control processes and medical product lifecycle development Working knowledge of biocompatibility, fluid dynamics, or clinical workflows is a plus Strong systems thinking across hardware, software, and biology Effective communicator and technical project coordinator Detail-oriented with a high sense of ownership Comfortable working in early-stage, cross-functional teams Adaptable and hands-on, with the ability to shift between technical depth and high-level coordination Experience managing or guiding cross-functional engineering teams Proven track record of technical leadership and systems integration in regulated medical products
Every Organ Wasted is a Life Not Saved.
TransMedics, Inc. is a commercial-stage medical technology company transforming organ transplant therapy for patients worldwide. Our mission is to help save more patients lives by increasing access to viable donor organs for those who are awaiting an organ transplant. To accomplish this mission, we partner closely with transplant stakeholders worldwide and help expand their access to healthy donor organs, while delivering the highest quality technology, service, clinical care and outcomes.
Driven by a passion for improving patient care, we make the impossible possible and keep our employees at the center of everything we do. Together, we strive to enhance the quality of life for transplant recipients and their families, fostering hope and healing in the journey toward better health.
Maximize your potential at TransMedics, Inc.
www.TransMedics.com
TransMedics is an equal opportunity employer and does not discriminate on the basis of race, color, religion, sex, national origin, marital status, age, disability or protected veteran status, or any other characteristic protected by law. We are committed to creating an inclusive environment for all employees.
Seniority level
Seniority level
Mid-Senior level Employment type
Employment type
Full-time Job function
Job function
Information Technology Industries
Medical Equipment Manufacturing Referrals increase your chances of interviewing at TransMedics, Inc. by 2x Sign in to set job alerts for Principal System Engineer roles.
Section Lead / Sr Manager System Engineer
Tewksbury, MA $124,000.00-$250,000.00 2 weeks ago Acton, MA $138,000.00-$207,000.00 2 weeks ago Senior Systems Engineer Ethernet Switches and Software
Wilmington, MA $125,250.00-$187,875.00 6 days ago Andover, MA $101,000.00-$203,000.00 7 hours ago Senior R&D Engineer - System Architecture (Italy based)
Section Lead / Manager Systems Engineering
Tewksbury, MA $101,000.00-$203,000.00 2 weeks ago Tewksbury, MA $82,000.00-$164,000.00 3 weeks ago Senior R&D Engineer - System Architecture (Italy based)
Woburn, MA $82,000.00-$164,000.00 7 hours ago Senior Software Engineer, Mission System (Maritime)
Boston, MA $168,000.00-$252,000.00 2 weeks ago Amesbury, MA $120,000.00-$170,000.00 1 week ago FAST Labs - Systems Engineer I&T Lead - $20K Sign On Bonus
Merrimack, NH $130,355.00-$221,603.00 2 weeks ago Senior Systems Engineer for GNC Requirements and Interfaces
Cambridge, MA $82,300.00-$205,750.00 19 hours ago Boston, MA $134,000.00-$254,000.00 1 day ago Boston, MA $136,000.00-$169,500.00 1 month ago Cambridge, MA $82,300.00-$205,750.00 5 days ago SIM-2 Product Owner Principal Systems Engineer
Woburn, MA $101,000.00-$203,000.00 1 week ago Woburn, MA $82,000.00-$164,000.00 1 week ago Cambridge, MA $82,300.00-$205,750.00 2 weeks ago Nashua, NH $182,000.00-$200,000.00 3 weeks ago Nashua, NH $182,000.00-$200,000.00 2 months ago Senior Systems Engineer - Must have an Active TS / SCI Clearance
Senior System Software Engineer, Cloud Software and Infrastructure
Westford, MA $184,000.00-$287,500.00 1 day ago Were unlocking community knowledge in a new way. Experts add insights directly into each article, started with the help of AI. #J-18808-Ljbffr