Neurocrine Biosciences
Scientist / Sr. Scientist, Analytical Chemistry
Neurocrine Biosciences, San Diego, California, United States, 92189
Overview
Scientist / Sr. Scientist, Analytical Chemistry – Neurocrine Biosciences. This role focuses on developing and executing instrumental methods of analysis for development compounds, drug substances, raw materials, intermediates, drug product and packaging materials to support assay development based on new and existing methodologies. The position coordinates and supports day-to-day operations in an Analytical Development GMP lab, with emphasis on GMP laboratory workflows. Responsibilities include scheduling instrument calibrations, maintenance and qualification activities, and ensuring full GMP compliance while supporting continuous improvement of lab processes and equipment readiness. Your Contributions (include, But Are Not Limited To)
Develops and executes instrumental methods (e.g. HPLC, GC, TGA, DSC, MS, FTIR) of analyses for development compounds, drug substances, raw materials, intermediates, drug product, and packaging materials Accurately follows established test methods, procedures, and pharmacopeia chapters (e.g. Dissolution) to generate data essential for strategic decision making Serve as the primary point of contact for all instrument-related activities and maintain equipment inventory, calibration and service records in compliance with GMP regulations Coordinates vendors service calls for repair and maintenance of laboratory instruments, with training perform routine maintenance of laboratory instrumentation, maintains complete and accurate records of instrument service and repairs in conformance with company SOPs and policies With supervision and as appropriate, assists investigations for out of specification, out of trend, and/or anomalous results Participates in internal and external audits as SME for lab instrumentation Support training of GMP lab staff on procedures, GMP requirements and safety protocols Coordinate daily lab operations Maintains complete and accurate records of laboratory work in conformance with company standard operating procedures (SOPs) and training Provides detailed reviews of peer generated data as well as that generated from contracted service providers Maintains the inventory of GMP laboratory consumables and clean glassware Performs other duties as assigned Requirements
BS/BA degree in chemistry or closely related field and 2+ years of pharmaceutical industry experience in an R&D/QC setting, including conducting HPLC analysis and troubleshooting, evaluating analytical data and drawing meaningful conclusions MS/MA degree in chemistry or closely related field preferred and some similar industry experience noted above PhD in chemistry or closely related field and some industry or relevant experience a plus Proficient in using MS-Excel, MS-Word as well as data systems for computer-controlled instrumentation Practical working knowledge of conducting HPLC analysis and troubleshooting Some expertise in evaluating analytical data and drawing meaningful conclusions Knowledge of cGMP expectations for laboratory records and quality systems Ability to provide ideas for process improvements Recognizes fundamental anomalies in data points and identifies issues in experiments / processes Begins to understand how to think outside of the technical process and consider the impact decisions will have on the broader scientific goals Strong knowledge of one scientific discipline Good knowledge of scientific principles, methods and techniques Good knowledge and demonstrated ability working with a variety of laboratory equipment/tools Ability to work as part of a team of individuals to meet goals, tasks in a timeline driven setting Strong computer skills Good communications, problem-solving, analytical thinking skills Detail oriented Ability to meet deadlines Good project management skills EEO Statement
Neurocrine Biosciences is an EEO/Disability/Vets employer. We are committed to building a workplace of belonging, respect, and empowerment, and we recognize there are a variety of ways to meet our requirements. We are looking for the best candidate for the job and encourage you to apply even if your experience or qualifications don’t line up to exactly what we have outlined in the job description. Compensation and Benefits
The annual base salary we reasonably expect to pay is $88,000.00-$127,550.00. Individual pay decisions depend on various factors, such as primary work location, complexity and responsibility of role, job duties/requirements, and relevant experience and skills. In addition, this position offers an annual bonus with a target of 20% of the earned base salary and eligibility to participate in our equity based long term incentive program. Benefits offered include a retirement savings plan (with company match), paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage in accordance with the terms and conditions of the applicable plans. Notes
Get notified about new Analytical Scientist jobs in
San Diego, CA . Seniority level
Mid-Senior level Employment type
Full-time Job function
Research, Analyst, and Information Technology
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Scientist / Sr. Scientist, Analytical Chemistry – Neurocrine Biosciences. This role focuses on developing and executing instrumental methods of analysis for development compounds, drug substances, raw materials, intermediates, drug product and packaging materials to support assay development based on new and existing methodologies. The position coordinates and supports day-to-day operations in an Analytical Development GMP lab, with emphasis on GMP laboratory workflows. Responsibilities include scheduling instrument calibrations, maintenance and qualification activities, and ensuring full GMP compliance while supporting continuous improvement of lab processes and equipment readiness. Your Contributions (include, But Are Not Limited To)
Develops and executes instrumental methods (e.g. HPLC, GC, TGA, DSC, MS, FTIR) of analyses for development compounds, drug substances, raw materials, intermediates, drug product, and packaging materials Accurately follows established test methods, procedures, and pharmacopeia chapters (e.g. Dissolution) to generate data essential for strategic decision making Serve as the primary point of contact for all instrument-related activities and maintain equipment inventory, calibration and service records in compliance with GMP regulations Coordinates vendors service calls for repair and maintenance of laboratory instruments, with training perform routine maintenance of laboratory instrumentation, maintains complete and accurate records of instrument service and repairs in conformance with company SOPs and policies With supervision and as appropriate, assists investigations for out of specification, out of trend, and/or anomalous results Participates in internal and external audits as SME for lab instrumentation Support training of GMP lab staff on procedures, GMP requirements and safety protocols Coordinate daily lab operations Maintains complete and accurate records of laboratory work in conformance with company standard operating procedures (SOPs) and training Provides detailed reviews of peer generated data as well as that generated from contracted service providers Maintains the inventory of GMP laboratory consumables and clean glassware Performs other duties as assigned Requirements
BS/BA degree in chemistry or closely related field and 2+ years of pharmaceutical industry experience in an R&D/QC setting, including conducting HPLC analysis and troubleshooting, evaluating analytical data and drawing meaningful conclusions MS/MA degree in chemistry or closely related field preferred and some similar industry experience noted above PhD in chemistry or closely related field and some industry or relevant experience a plus Proficient in using MS-Excel, MS-Word as well as data systems for computer-controlled instrumentation Practical working knowledge of conducting HPLC analysis and troubleshooting Some expertise in evaluating analytical data and drawing meaningful conclusions Knowledge of cGMP expectations for laboratory records and quality systems Ability to provide ideas for process improvements Recognizes fundamental anomalies in data points and identifies issues in experiments / processes Begins to understand how to think outside of the technical process and consider the impact decisions will have on the broader scientific goals Strong knowledge of one scientific discipline Good knowledge of scientific principles, methods and techniques Good knowledge and demonstrated ability working with a variety of laboratory equipment/tools Ability to work as part of a team of individuals to meet goals, tasks in a timeline driven setting Strong computer skills Good communications, problem-solving, analytical thinking skills Detail oriented Ability to meet deadlines Good project management skills EEO Statement
Neurocrine Biosciences is an EEO/Disability/Vets employer. We are committed to building a workplace of belonging, respect, and empowerment, and we recognize there are a variety of ways to meet our requirements. We are looking for the best candidate for the job and encourage you to apply even if your experience or qualifications don’t line up to exactly what we have outlined in the job description. Compensation and Benefits
The annual base salary we reasonably expect to pay is $88,000.00-$127,550.00. Individual pay decisions depend on various factors, such as primary work location, complexity and responsibility of role, job duties/requirements, and relevant experience and skills. In addition, this position offers an annual bonus with a target of 20% of the earned base salary and eligibility to participate in our equity based long term incentive program. Benefits offered include a retirement savings plan (with company match), paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage in accordance with the terms and conditions of the applicable plans. Notes
Get notified about new Analytical Scientist jobs in
San Diego, CA . Seniority level
Mid-Senior level Employment type
Full-time Job function
Research, Analyst, and Information Technology
#J-18808-Ljbffr