Summit Therapeutics, Inc.
Overview
Ivonescimab, known as SMT112, is a novel, potential first-in-class investigational bispecific antibody that combines immunotherapy (PD-1 blockade) with anti-angiogenesis (VEGF blockade) into a single molecule. Summit has begun its clinical development of ivonescimab in NSCLC, with three active Phase III trials: HARMONi, HARMONi-3, and HARMONi-7. HARMONi is a Phase III trial evaluating ivonescimab with chemotherapy vs placebo plus chemotherapy in EGFR-mutated locally advanced or metastatic non-squamous NSCLC after progression on a 3rd generation EGFR TKI (e.g., osimertinib). HARMONi-3 is a Phase III trial evaluating ivonescimab with chemotherapy vs pembrolizumab with chemotherapy in first-line metastatic NSCLC. HARMONi-7 is a Phase III trial evaluating ivonescimab monotherapy vs pembrolizumab monotherapy in first-line metastatic NSCLC with high PD-L1 expression. Ivonescimab is investigational and not approved by regulatory authorities in Summit’s license territories (including the U.S. and Europe). It was approved for marketing authorization in China in May 2024 and has received Fast Track designation by the U.S. FDA for the HARMONi setting.
Role
Assistant Controller will manage the accounting process, lead the accounting close and financial audits. Other responsibilities will apply as the business evolves.
Responsibilities
Oversee all aspects of accounting, including general ledger, cost accounting, accounts payable and payroll. Drive the preparation and review of clinical trials and contract manufacturing related accruals and prepayments, and related reconciliations. Perform and/or review various technical accounting analyses. Maintain internal and operational controls to monitor performance and comply with SOX 404, as required. Ensure completeness and accuracy of month-end close tasks; oversee journal entries, balance sheet reconciliations, financial flux, key judgements, internal controls and management reporting. Act as primary liaison with external auditors; prepare and coordinate material for quarterly reviews and annual audits. Collaborate with supply chain, manufacturing, and quality teams to monitor drug inventory accounting, ensuring accurate valuation, inventory reconciliation, obsolescence and excess stock practices and compliance. Partner with FP&A and the business to provide financial insight for budgets and forecasting. Assist with compilation of information for tax compliance items, including annual provisions/returns and other tax-related items; review external tax advisors’ deliverables. Maintain focus on continuous improvement to accelerate financial close and increase efficiency of accounting and reporting processes. Support ERP implementation and upgrades as appropriate. Develop and update accounting policies and documentation. Mentor and support members of the accounting team. Other duties as assigned.
Experience, Education, and Specialized Knowledge and Skills
Bachelor’s or Master’s in accounting; CPA preferred. 10+ years of progressive experience in public and private accounting. Experience in biotech or life sciences industry required. Demonstrate intellectual curiosity by interacting with business leaders to understand operational activities and ensure appropriate accounting treatment. Thorough knowledge of US GAAP principles. Ability to operate in a fast-paced environment. Attention to detail, accuracy and confidentiality. Excellent organizational, management, analytical and decision-making skills. Ability to work cross-functionally across geographies. Impeccable integrity and strong work ethic.
The pay range for this role is $215,000 - $235,000 annually. Actual compensation packages are based on several factors, including skill set, depth of experience, certifications, and work location. The total compensation package may include bonus, stock, benefits and/or other variable compensation. Summit does not accept referrals from employment businesses/agencies for vacancies posted on this site without prior written authorization.
Employment details
Seniority level: Director Employment type: Full-time Job function: Strategy/Planning and Information Technology
Location notes and salary ranges reflect current postings and may vary by location and time. Referrals increase your chances of interviewing at Summit Therapeutics, Inc. by 2x.
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Ivonescimab, known as SMT112, is a novel, potential first-in-class investigational bispecific antibody that combines immunotherapy (PD-1 blockade) with anti-angiogenesis (VEGF blockade) into a single molecule. Summit has begun its clinical development of ivonescimab in NSCLC, with three active Phase III trials: HARMONi, HARMONi-3, and HARMONi-7. HARMONi is a Phase III trial evaluating ivonescimab with chemotherapy vs placebo plus chemotherapy in EGFR-mutated locally advanced or metastatic non-squamous NSCLC after progression on a 3rd generation EGFR TKI (e.g., osimertinib). HARMONi-3 is a Phase III trial evaluating ivonescimab with chemotherapy vs pembrolizumab with chemotherapy in first-line metastatic NSCLC. HARMONi-7 is a Phase III trial evaluating ivonescimab monotherapy vs pembrolizumab monotherapy in first-line metastatic NSCLC with high PD-L1 expression. Ivonescimab is investigational and not approved by regulatory authorities in Summit’s license territories (including the U.S. and Europe). It was approved for marketing authorization in China in May 2024 and has received Fast Track designation by the U.S. FDA for the HARMONi setting.
Role
Assistant Controller will manage the accounting process, lead the accounting close and financial audits. Other responsibilities will apply as the business evolves.
Responsibilities
Oversee all aspects of accounting, including general ledger, cost accounting, accounts payable and payroll. Drive the preparation and review of clinical trials and contract manufacturing related accruals and prepayments, and related reconciliations. Perform and/or review various technical accounting analyses. Maintain internal and operational controls to monitor performance and comply with SOX 404, as required. Ensure completeness and accuracy of month-end close tasks; oversee journal entries, balance sheet reconciliations, financial flux, key judgements, internal controls and management reporting. Act as primary liaison with external auditors; prepare and coordinate material for quarterly reviews and annual audits. Collaborate with supply chain, manufacturing, and quality teams to monitor drug inventory accounting, ensuring accurate valuation, inventory reconciliation, obsolescence and excess stock practices and compliance. Partner with FP&A and the business to provide financial insight for budgets and forecasting. Assist with compilation of information for tax compliance items, including annual provisions/returns and other tax-related items; review external tax advisors’ deliverables. Maintain focus on continuous improvement to accelerate financial close and increase efficiency of accounting and reporting processes. Support ERP implementation and upgrades as appropriate. Develop and update accounting policies and documentation. Mentor and support members of the accounting team. Other duties as assigned.
Experience, Education, and Specialized Knowledge and Skills
Bachelor’s or Master’s in accounting; CPA preferred. 10+ years of progressive experience in public and private accounting. Experience in biotech or life sciences industry required. Demonstrate intellectual curiosity by interacting with business leaders to understand operational activities and ensure appropriate accounting treatment. Thorough knowledge of US GAAP principles. Ability to operate in a fast-paced environment. Attention to detail, accuracy and confidentiality. Excellent organizational, management, analytical and decision-making skills. Ability to work cross-functionally across geographies. Impeccable integrity and strong work ethic.
The pay range for this role is $215,000 - $235,000 annually. Actual compensation packages are based on several factors, including skill set, depth of experience, certifications, and work location. The total compensation package may include bonus, stock, benefits and/or other variable compensation. Summit does not accept referrals from employment businesses/agencies for vacancies posted on this site without prior written authorization.
Employment details
Seniority level: Director Employment type: Full-time Job function: Strategy/Planning and Information Technology
Location notes and salary ranges reflect current postings and may vary by location and time. Referrals increase your chances of interviewing at Summit Therapeutics, Inc. by 2x.
#J-18808-Ljbffr