Director, Enterprise Data Architecture & AI Solutions

Working with Us

Challenging. Meaningful. Life-changing. Those aren’t words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You’ll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more: careers.bms.com/working-with-us

RayzeBio, a Bristol Myers Squibb company, is a dynamic biotechnology company headquartered in San Diego, CA. The company is focused on improving survival of people with cancer by harnessing the power of targeted radioisotopes. RayzeBio is developing innovative drugs against targets of solid tumors. Led by a successful and experienced entrepreneurial team, RayzeBio aims to be the global leader in radiopharmaceuticals.

Position

RayzeBio is seeking a Director, Enterprise Data Architecture & AI Solutions to architect, integrate, and scale data and AI capabilities supporting our mission to advance next-generation radiopharmaceuticals. This highly visible leadership role spans cross-functional teams—including Commercial, Medical Affairs, Clinical Operations, Early Development, and Manufacturing—with a sharp focus on harmonizing enterprise data architecture and accelerating the application of AI/ML for real-world impact.

The ideal candidate combines technical acumen with systems integration expertise and stakeholder savvy, enabling both near-term wins and strategic transformation across RayzeBio’s rapidly growing organization.

The candidate will collaborate with BMS and the BI&T team to ensure all initiatives are not duplicative and are leveraging BMS “know how” and capabilities as appropriate.

The selected candidate will be required to travel regularly to all three sites (San Diego, Indianapolis, and Princeton) collaborating with teams across RayzeBio and BMS, spending 30% of the time at one of these three sites.

Key Responsibilities

• Enterprise Data Architecture & Platform Enablement: Design, build, and continuously improve RayzeBio’s data lakehouse architecture to unlock analytics, reporting, and AI for enterprise users.
• Develop enterprise data models and semantic layers tailored for radiopharmaceutical workflows, enabling scalable self-service analytics and operational insights.
• Define integration strategy across enterprise applications (clinical, ERP, CRM, manufacturing, compliance) balancing traceability, integrity, and regulatory requirements.

• Applied AI/ML Solution Design: Identify and evaluate high-value opportunities for AI/ML in early development, clinical operations, supply chain, commercial analytics, and scientific knowledge management.
• Lead solution design for practical AI/ML pilots—coordinating in-house or external partners, ensuring alignment with RayzeBio’s digital and enterprise standards.
• Establish data readiness protocols for machine learning (annotation, pipeline integration, model monitoring/feedback, and secure deployment).

• Enterprise Systems Integration & Scale-Up: Own enterprise systems integration, dataflow design, and harmonization as RayzeBio transitions from pre-commercial to commercial-stage operations.
• Implement master data management solutions supporting unified product, customer, clinical trial, and manufacturing data domains.
• Collaborate with platform engineering, infrastructure, and partner teams to maximize interoperability and leverage best-in-class/reusable assets.

• Governance, Quality, & Compliance: Lead metadata management, master data governance, and stewardship processes—ensuring alignment with GxP, privacy, and commercial compliance requirements.
• Set and monitor high standards for data quality, system validation, and audit-readiness in collaboration with business and technical stakeholders.
• Champion cross-functional data governance (ownership, access, lineage) in a highly regulated, complex data ecosystem.

• Stakeholder Leadership & Team Growth: Serve as strategic advisor on data, analytics, and AI readiness—supporting business, R&D, and executive teams with actionable architectural guidance.
• Influence and align cross-functional partners toward shared goals and enterprise data priorities; champion digital-first and Gen AI-enabled innovations.
• Establish and maintain strong relationships with BMS stakeholders.
• Recruit, onboard, and mentor a small, high-impact team as RayzeBio scales.

Required Qualifications

• BS Degree
• Minimum 10+ years in data architecture, analytics platform design, or commercial data operations—ideally within biotech, pharma, or healthcare.
• Proven record designing and scaling cloud-native data platforms/data models in multifaceted settings (including early-stage or growth-phase companies).
• Experience driving requirements definition, collaborating with engineering, and integrating complex, heterogeneous data systems.
• Deep understanding of oncology or radiopharmaceutical data (commercial, clinical, medical, or R&D).
• Demonstrated ability to operate independently and prioritize in a lean, entrepreneurial environment.
• Strategic and systems-oriented, with a passion for building scalable solutions and driving cross-enterprise alignment.
• Energetic self-starter-comfortable managing uncertainty, setting priorities, and influencing senior stakeholders.
• Highly collaborative; able to synthesize diverse viewpoints and translate ambiguous needs into concrete data/AI roadmaps.
• Pragmatic communicator—adept at concise documentation, presenting actionable concepts, and driving stakeholder engagement.

Preferred Experience

• Experience in oncology-driven biotech or pharma, especially pre-commercial/early commercial stage.
• Working familiarity with life sciences regulatory frameworks (GxP, privacy, retention, commercial).
• Direct exposure to ML/AI in healthcare (predictive analytics, NLP, Gen AI, or decision support).
• Hands-on prototyping experience (Databricks, cloud notebooks, automation tools, etc.).
• Led or contributed to AI/ML/data platform initiatives within cross-functional/product teams.

Why Join RayzeBio?

This is a rare opportunity to lead the AI transformation of a high-growth biotech, directly impacting our programs and patients, and shaping the future of data-driven medicine—supported by the vision and resources of Bristol Myers Squibb. Selective hybrid flexibility may be considered as noted above.

RayzeBio and Bristol Myers Squibb are equal opportunity employers. All employment decisions are made without regard to race, color, religion, gender, sexual orientation, gender identity, age, national origin, or disability status.

#RayzeBio

If you come across a role that intrigues you but doesn’t perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Compensation Overview

San Diego - RayzeBio - CA: $207,633 - $251,602. The starting compensation range(s) for this role are listed above for a full-time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee’s work schedule, job-related knowledge, and experience. Final, individual compensation will be decided based on demonstrated experience.

Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit careers.bms.com/life-at-bms/.

Benefit offerings are subject to the terms and conditions of the applicable plans then in effect and may include the following: Medical, pharmacy, dental and vision care. Wellbeing support such as the BMS Living Life Better program and employee assistance programs (EAP). Financial well-being resources and a 401(K). Financial protection benefits such as short- and long-term disability, life insurance, supplemental health insurance, business travel protection and survivor support. Work-life programs include paid national holidays and optional holidays, Global Shutdown Days between Christmas and New Year’s holiday, up to 120 hours of paid vacation, up to two paid days to volunteer, sick time off, and summer hours flexibility. Parental, caregiver, bereavement, and military leave. Family care services such as adoption and surrogacy reimbursement, fertility/infertility benefits, support for traveling mothers, and child, elder and pet care resources. Other perks like tuition reimbursement and a recognition program.

Uniquely Interesting Work, Life-changing Careers
With a single vision as inspiring as “Transforming patients’ lives through science”, every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol

BMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role.

Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations in completing this application, or in any part of the recruitment process, direct your inquiries to Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: careers.bms.com/california-residents/

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.