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Umbilical Life

Machine Learning Research Engineer (Senior/Principal/Staff)

Umbilical Life, WorkFromHome

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Overview

I am working with a leading Tech Bio company in Boston, seeking a Senior (Senior/Principal/Staff Scientist) Machine Learning Research Engineer to lead the development of their Biological AI Model. The candidate should be local to Boston on a weekly basis.

Key Responsibilities

  • Design and implement core AI/ML models for simulating cellular systems using multi-omics and single-cell data.
  • Develop novel architectures e.g. Graph Neural Networks, Causal Inference, Transformers, diffusion models, VAE etc tailored to biological complexity.
  • Contribute to the strategic direction of modeling efforts , helping define what to build, why, and how.
  • Lead model design from prototyping to production .
  • Guide internal thinking around biological networks, perturbation models , and high-dimensional cellular data.
  • Support cross-functional collaboration and help define a scalable modeling stack and modeling best practices across the company.

Ideal Profile

  • MS or PhD in Computer Science, Physics, Applied Math, or similar , with a strong focus on AI/ML.
  • Strong track record in research outputs on single-cell data and AI method development.
  • Expertise in building models using GNNs, VAEs, Transformers , reinforcement learning , or other deep learning approaches.
  • Strong proficiency in Python and deep learning frameworks such as PyTorch, TensorFlow or JAX.
  • Exposure to single-cell data (e.g., scRNA-seq, spatial omics) .
  • Ability to abstract and model complex biological processes from data/physics/ML perspectives.
  • Experience with scaling models across biological levels — from individual cells to tissues and whole organisms — and multi-scale integration is a strong plus.
  • Experience working on noisy, high-dimensional, multi-modal biological data .
  • Curious, collaborative, and comfortable in fast-moving, exploratory R&D environments.
  • Previous experience with Virtual Cell Models is a plus.

Seniority level

  • Mid-Senior level

Employment type

  • Full-time

Job function

  • Science and Engineering

Industries

  • Biotechnology Research and Pharmaceutical Manufacturing

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