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Nautilus Biotechnology

Director, Operations

Nautilus Biotechnology, San Carlos

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Overview

Join to apply for the Director, Operations role at Nautilus Biotechnology .

Base pay range

$189,000.00/yr - $252,000.00/yr

At Nautilus, we have a big and important mission: improve the health of millions by unleashing the potential of the proteome to accelerate drug development and enable a new world of precision and personalized medicine. We are developing a single-molecule protein analysis platform of unprecedented sensitivity, scale, and ease of use that we believe will democratize access to the proteome – one of the most dynamic and valuable sources of biological insight. To accomplish this, we are pursuing hard scientific problems with an entrepreneurial mindset and creating a world-class team of builders, innovators, and dreamers across a wide range of disciplines.

We are hiring for a Director, Operations to join our growing team. This role is a critical leadership position responsible for ensuring Nautilus\'s Instrument and Flow Cell Operations meet commercialization timelines and compliance standards. As a leader in this position, you will translate the company\'s strategy into clear operational roadmaps and act as a trusted advisor to the executive team. You will have the opportunity to build and manage high-performing teams and contribute to a mission-driven culture as you help us bring our platform to the world.

Responsibilities

  • Develop and execute operational strategies aligned with company objectives.
  • Manage timelines and deliverables for product development and commercialization.
  • Oversee the production of flowcells and instruments.
  • Manage the supply chain and logistics, including sourcing, inventory, and distribution of materials and products. You\'ll also be responsible for architecting complex supply chains with multiple partners.
  • Ensure operations comply with FDA, GMP, ISO, and other relevant regulatory standards.
  • Control operational budgets and resource allocation.
  • Collaborate with cross-functional teams, including R&D, QA/QC, and commercial teams, to drive results.
  • Implement and optimize systems for quality assurance and control.
  • Lead process improvement initiatives to enhance efficiency and scalability.
  • Build and manage teams across manufacturing, supply chain, and logistics, fostering a culture of accountability and innovation.
  • Report on operational performance metrics to senior management and adjust tactics as needed.
  • Lead teams through periods of rapid growth, transformation, and scaling with clarity and confidence.

Qualifications

  • Education: Bachelor’s or Master’s in Life Sciences, Engineering, or Business is required; an MBA is often preferred
  • Experience: 6-10 years of experience working in Biotech, Pharmaceutical Operations, or Medical Device companies, including leadership roles
  • Skills: Strong knowledge of GMP/GxP compliance and regulatory landscapes is required.

Preferred Qualifications

  • Experience in Lean Manufacturing and Six Sigma
  • Experience implementing ERP, MES, or Advanced Planning Solutions
  • Experience with semiconductor manufacturing and packaging processes
  • Experience with a product introduction that achieved 510K compliance
  • Experience leading operations at a company that scaled to over $500M

Nautilus Team Culture

  • We are determined to do whatever it takes to get our platform into the hands of researchers who will use it to upend the status quo in basic research and healthcare.
  • We work on cross functional teams, wear many hats, take risks to work through uncertainty, enjoy working collaboratively on challenging problems, and celebrate one another’s victories.
  • We go above and beyond, but also strive to provide a supportive atmosphere of colleagues who are willing to lend a helping hand and make working at Nautilus not only fulfilling in its end goals, but enjoyable on a day-to-day basis.

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