Bristol-Myers Squibb
Principal Scientist, Oral Product Development
Bristol-Myers Squibb, New Brunswick, New Jersey, us, 08933
Overview
Working with Us
– Challenging. Meaningful. Life-changing. Bristol Myers Squibb offers opportunities to grow and thrive through diverse, high-impact work across departments, including drug product development and cell therapy breakthroughs. We emphasize balance and flexibility with competitive benefits and programs to support goals at work and in personal life. Career growth is encouraged in a collaborative environment. We are committed to inclusion and to a work environment where diversity of thought and background is valued. Position Summary
Bristol Myers Squibb is seeking a principal scientist to join the Oral Product Development group within the Drug Product Development function. The group supports the formulation and process development of drug candidates from preclinical stage to commercial process readiness. This position is responsible for formulation design, development, characterization, and technology transfer to enable development of small molecule drug products (DPs). The incumbent will be accountable as an individual contributor and as a formulation matrix team lead to support formulation development and provide guidance on drug product control strategy across all stages of development. Key Responsibilities
Collaborate across BMS sites with Drug Product, Analytical, API, Quality, and Regulatory functions to execute drug product formulation/process development, formulation strategies, control strategies, and support of drug application submissions and approvals. Lead design, development, and characterization of robust small molecule drug product formulations. Develop oral formulations for clinical studies and commercialization. Lead formulation and process development, evaluating strategies to enhance oral bioavailability, stability, and processability. Support preparation of CMC regulatory documents. Support departmental initiatives for assigned projects and methodologies. Maintain safety, regulatory, and compliance standards related to pharmaceutical development. Prepare technical reports, batch records, SOPs, publications, and oral presentations as required. Collaborate with cross-functional teams to optimize formulations and enable technology transfer to CMOs and other sites for manufacturing and scale-up. Develop, coach and mentor others. Qualifications & Experience
Required: Completed BS and minimum of 9 years; MS and minimum of 6 years; or Ph.D. and minimum of 4 years in Pharmaceutical Science, Chemical Engineering or related discipline with pharmaceutical development experience. Experience in formulation development and pharmaceutical processing related to drug product development; hands-on experience. Strong understanding of drug substance, excipients, pharmaceutical unit operations (blending, milling, sieving, granulation, tableting, encapsulation, coating, spray drying), intermediate and critical quality attributes, statistics, risk assessment approaches, and cGMP principles. Experience building the CMC dossier for regulatory submissions as an author/reviewer. Basic knowledge of regulatory requirements. Demonstrated problem-solving and troubleshooting skills; strong capabilities in experimental design and execution. Ability to work independently and provide leadership, guidance, and training to others within the department. Strong verbal and written communication skills; strong interpersonal skills and ability to lead or participate in cross-functional teams. Ability to manage and coordinate leading workgroups, cross-functional teams, strategy development/implementation, and cultural initiatives. Note: This job description reflects the responsibilities and requirements for the role and does not intend to capture every duty that may be assigned. Compensation & Benefits
New Brunswick, NJ, US: $138,190 - $167,457 plus additional incentive cash and stock opportunities (based on eligibility). Starting pay is based on skills, experience, and location. Eligibility for specific benefits may vary by job and location. Benefits may include medical, dental, vision, wellness programs, 401(k), disability, life insurance, travel protection, paid holidays, vacation, volunteer time, parental and family leave, tuition reimbursement, and recognition programs. For more details, visit the careers site. Uniquely Interesting Work, Life-changing Careers
With a unifying vision to transform patients’ lives through science, every BMS employee contributes to work that goes beyond ordinary. We support a culture of inclusion, collaboration, and accountability, where individual talents and perspectives are valued. On-site Protocol
BMS assigns occupancy types based on role responsibilities (site-essential, site-by-design, field-based, remote-by-design). Site-essential roles require 100% onsite presence; site-by-design roles may permit hybrid work with at least 50% onsite. This may include travel to visit customers, patients, or partners as needed. BMS provides reasonable accommodations and a pathway for accessibility in recruitment and employment. For accommodations inquiries, contact adastaffingsupport@bms.com. For equal employment opportunity information, visit the Careers site. We encourage vaccination and boosters as part of well-being. BMS will consider applicants with arrest or conviction records as permitted by law. If located in Los Angeles County, additional information is available on the California residents page. All data collected in connection with role applications will be handled per applicable privacy policies.
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Working with Us
– Challenging. Meaningful. Life-changing. Bristol Myers Squibb offers opportunities to grow and thrive through diverse, high-impact work across departments, including drug product development and cell therapy breakthroughs. We emphasize balance and flexibility with competitive benefits and programs to support goals at work and in personal life. Career growth is encouraged in a collaborative environment. We are committed to inclusion and to a work environment where diversity of thought and background is valued. Position Summary
Bristol Myers Squibb is seeking a principal scientist to join the Oral Product Development group within the Drug Product Development function. The group supports the formulation and process development of drug candidates from preclinical stage to commercial process readiness. This position is responsible for formulation design, development, characterization, and technology transfer to enable development of small molecule drug products (DPs). The incumbent will be accountable as an individual contributor and as a formulation matrix team lead to support formulation development and provide guidance on drug product control strategy across all stages of development. Key Responsibilities
Collaborate across BMS sites with Drug Product, Analytical, API, Quality, and Regulatory functions to execute drug product formulation/process development, formulation strategies, control strategies, and support of drug application submissions and approvals. Lead design, development, and characterization of robust small molecule drug product formulations. Develop oral formulations for clinical studies and commercialization. Lead formulation and process development, evaluating strategies to enhance oral bioavailability, stability, and processability. Support preparation of CMC regulatory documents. Support departmental initiatives for assigned projects and methodologies. Maintain safety, regulatory, and compliance standards related to pharmaceutical development. Prepare technical reports, batch records, SOPs, publications, and oral presentations as required. Collaborate with cross-functional teams to optimize formulations and enable technology transfer to CMOs and other sites for manufacturing and scale-up. Develop, coach and mentor others. Qualifications & Experience
Required: Completed BS and minimum of 9 years; MS and minimum of 6 years; or Ph.D. and minimum of 4 years in Pharmaceutical Science, Chemical Engineering or related discipline with pharmaceutical development experience. Experience in formulation development and pharmaceutical processing related to drug product development; hands-on experience. Strong understanding of drug substance, excipients, pharmaceutical unit operations (blending, milling, sieving, granulation, tableting, encapsulation, coating, spray drying), intermediate and critical quality attributes, statistics, risk assessment approaches, and cGMP principles. Experience building the CMC dossier for regulatory submissions as an author/reviewer. Basic knowledge of regulatory requirements. Demonstrated problem-solving and troubleshooting skills; strong capabilities in experimental design and execution. Ability to work independently and provide leadership, guidance, and training to others within the department. Strong verbal and written communication skills; strong interpersonal skills and ability to lead or participate in cross-functional teams. Ability to manage and coordinate leading workgroups, cross-functional teams, strategy development/implementation, and cultural initiatives. Note: This job description reflects the responsibilities and requirements for the role and does not intend to capture every duty that may be assigned. Compensation & Benefits
New Brunswick, NJ, US: $138,190 - $167,457 plus additional incentive cash and stock opportunities (based on eligibility). Starting pay is based on skills, experience, and location. Eligibility for specific benefits may vary by job and location. Benefits may include medical, dental, vision, wellness programs, 401(k), disability, life insurance, travel protection, paid holidays, vacation, volunteer time, parental and family leave, tuition reimbursement, and recognition programs. For more details, visit the careers site. Uniquely Interesting Work, Life-changing Careers
With a unifying vision to transform patients’ lives through science, every BMS employee contributes to work that goes beyond ordinary. We support a culture of inclusion, collaboration, and accountability, where individual talents and perspectives are valued. On-site Protocol
BMS assigns occupancy types based on role responsibilities (site-essential, site-by-design, field-based, remote-by-design). Site-essential roles require 100% onsite presence; site-by-design roles may permit hybrid work with at least 50% onsite. This may include travel to visit customers, patients, or partners as needed. BMS provides reasonable accommodations and a pathway for accessibility in recruitment and employment. For accommodations inquiries, contact adastaffingsupport@bms.com. For equal employment opportunity information, visit the Careers site. We encourage vaccination and boosters as part of well-being. BMS will consider applicants with arrest or conviction records as permitted by law. If located in Los Angeles County, additional information is available on the California residents page. All data collected in connection with role applications will be handled per applicable privacy policies.
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