GlaxoSmithKline
Associate Director - Precision Medicine Data & Analytics
GlaxoSmithKline, Waltham, Massachusetts, United States, 02254
Key Responsibilities:
Oversee the analysis of complex biological data from clinical trials, ensuring robust interpretation and reporting for clinical study reports and regulatory submissions
Support the delivery of clinical biomarker data analysis to enable Oncology Translational Medicine strategies and decision making towards identification of the right patient, right drug, right dose at the right time
Integrate and analyze large-scale, high-dimensional, and multimodal biomarker datasets from internal and external sources to enhance our understanding of mechanisms of action, resistance, patient stratification and selection, new indications, and biologically driven combination strategies.
Collaborate with CPMS, Diagnostic, Translational Research and AI/ML teams to ensure complementary data analytics approaches are evaluated and applied to deliver the most meaningful insights into the data
Clear and timely communication of data analysis outputs and complex analytical principles & models to matrix team partners
Maintain data integrity principles aligned with human data quality standards
Support integration and analysis of academic biomarker partnership data and technology evaluation data generated by the Oncology Translational Medicine team
Execute internal and external (e.g. real world data) biomarker data analysis to support pipeline growth, including life cycle management plans (e.g. biomarker prevalence in patient populations, right patient/dose), and leveraging data analytics outputs to support decision making.
Execute advanced analytics and target/pathway analysis to support evaluation of due diligence business development asset evaluations.
Why you?
Basic Qualifications
PhD degree or equivalent computational biology, bioinformatics, machine learning experience/training
5+ years of experience in Pharma/Biotech or academic setting.
Experience with coding skills in R and/or Python and working knowledge of common bioinformatics databases, resources and tools
Experience dealing with next-generation sequencing data and working with oncology drugs or programs
Preferred Qualifications
If you have the following characteristics, it would be a plus: Experience communicating analytical principles and results to non-analytical colleagues and stakeholders
Experience working with and analyzing complex high dimensional datasets (e.g. single-cell and spatial transcriptomics, proteomics, cfDNA) by leveraging state of the art models and analytical approaches
Experience with GCP principals and working on clinical studies
Experience with data and metadata best practices (e.g. FAIR principles, data standards, cloud environment analytical tools)
Experiencing creating data visualization outputs and working with multi-disciplinary teams
Experience with statistical, analytical methods relevant to analysis of complex high dimensional heterogeneous datasets
Experience with GitHub, development of R Shiny applications/R markdown, and working in cloud or high-performance computing (HPC) environments is a plus.
Please visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees. Why GSK?
Uniting science, technology and talent to get ahead of disease together. GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale. People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people. If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US). GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law. Important notice to Employment businesses/ Agencies GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site. Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/
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Oversee the analysis of complex biological data from clinical trials, ensuring robust interpretation and reporting for clinical study reports and regulatory submissions
Support the delivery of clinical biomarker data analysis to enable Oncology Translational Medicine strategies and decision making towards identification of the right patient, right drug, right dose at the right time
Integrate and analyze large-scale, high-dimensional, and multimodal biomarker datasets from internal and external sources to enhance our understanding of mechanisms of action, resistance, patient stratification and selection, new indications, and biologically driven combination strategies.
Collaborate with CPMS, Diagnostic, Translational Research and AI/ML teams to ensure complementary data analytics approaches are evaluated and applied to deliver the most meaningful insights into the data
Clear and timely communication of data analysis outputs and complex analytical principles & models to matrix team partners
Maintain data integrity principles aligned with human data quality standards
Support integration and analysis of academic biomarker partnership data and technology evaluation data generated by the Oncology Translational Medicine team
Execute internal and external (e.g. real world data) biomarker data analysis to support pipeline growth, including life cycle management plans (e.g. biomarker prevalence in patient populations, right patient/dose), and leveraging data analytics outputs to support decision making.
Execute advanced analytics and target/pathway analysis to support evaluation of due diligence business development asset evaluations.
Why you?
Basic Qualifications
PhD degree or equivalent computational biology, bioinformatics, machine learning experience/training
5+ years of experience in Pharma/Biotech or academic setting.
Experience with coding skills in R and/or Python and working knowledge of common bioinformatics databases, resources and tools
Experience dealing with next-generation sequencing data and working with oncology drugs or programs
Preferred Qualifications
If you have the following characteristics, it would be a plus: Experience communicating analytical principles and results to non-analytical colleagues and stakeholders
Experience working with and analyzing complex high dimensional datasets (e.g. single-cell and spatial transcriptomics, proteomics, cfDNA) by leveraging state of the art models and analytical approaches
Experience with GCP principals and working on clinical studies
Experience with data and metadata best practices (e.g. FAIR principles, data standards, cloud environment analytical tools)
Experiencing creating data visualization outputs and working with multi-disciplinary teams
Experience with statistical, analytical methods relevant to analysis of complex high dimensional heterogeneous datasets
Experience with GitHub, development of R Shiny applications/R markdown, and working in cloud or high-performance computing (HPC) environments is a plus.
Please visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees. Why GSK?
Uniting science, technology and talent to get ahead of disease together. GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale. People and patients around the world count on the medicines and vaccines we make, so we’re committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people. If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US). GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law. Important notice to Employment businesses/ Agencies GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site. Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK’s compliance to all federal and state US Transparency requirements. For more information, please visit the Centers for Medicare and Medicaid Services (CMS) website at https://openpaymentsdata.cms.gov/
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