Takeda
Overview
Scientist Protein Chemistry role at Takeda. The position reports to Takeda’s Structural Biology organization and supports drug discovery programs by advancing production, characterization, and structural elucidation of proteins for biochemical assays, biophysical studies, and structure determination using methods such as x-ray crystallography or cryo-EM. The role involves in-house protein production, collaboration with external contract research organizations, and engagement with internal experts and cross-functional teams to achieve project goals.
Base pay range $111,800.00/yr - $175,670.00/yr
Responsibilities
Plan and execute protein production campaigns for protein reagents and/or structural biology efforts in collaboration with structural biologists and protein chemists using in-house production capabilities, equipment, and database resources.
Analyze proprietary and public information to positively impact structure determination efforts, reagent or antigen protein production and characterization, and/or antibody design, optimization, and characterization.
Collaborate and communicate with interdisciplinary teams, including structural biologists, protein chemists, in vitro pharmacologists, medicinal and computational chemists, and project management to advance pipeline projects.
Communicate protein production and characterization plans, priorities, results, and timelines to varied audiences.
Education & Competencies (Technical and Behavioral)
PhD degree in a scientific discipline (Structural Biology, Biophysics, Biochemistry/Enzymology, Protein Chemistry); MS with 6+ years or BS with 8+ years industry experience also considered; industry experience highly desirable.
Demonstrated track record of successful hands-on high-quality protein production (construct design, cloning, expression, purification, optimization, characterization) of protein reagents, antigens and/or antibodies or other biologics therapeutics for drug discovery teams.
Experience in protein production utilizing contract research organizations highly desirable.
Experience in design, expression and purification of membrane proteins and/or multi-protein complexes; knowledge of and/or experience in structural biology methodologies, biochemical and/or biophysical assays highly desirable.
Passion for learning and advancing protein production capabilities and drug discovery pipelines, including proactive investigation of new techniques and capabilities, software/hardware and innovative approaches.
Ability to work collaboratively in a fast-paced, matrixed environment with a proactive, collaborative mindset focused on therapeutic development.
Compensation and Benefits Takeda Compensation and Benefits Summary: We are committed to equitable pay and transparency in pay practices.
Location: Boston, MA
U.S. Base Salary Range $111,800.00 - $175,670.00
The actual base salary offered depends on qualifications, experience, and location, and will comply with applicable wage requirements. U.S. based employees may be eligible for incentives and benefits including medical, dental, vision, 401(k) with company match, disability and life insurance, tuition reimbursement, paid time off, holidays, and well-being programs.
EEO Statement Takeda is committed to creating a diverse workforce and providing equal employment opportunities to all employees and applicants without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or protected characteristics as defined by law.
Locations Boston, MA
Worker Type Employee
Worker Sub-Type Regular
Time Type Full time
Job Exempt Yes
It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment.
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Base pay range $111,800.00/yr - $175,670.00/yr
Responsibilities
Plan and execute protein production campaigns for protein reagents and/or structural biology efforts in collaboration with structural biologists and protein chemists using in-house production capabilities, equipment, and database resources.
Analyze proprietary and public information to positively impact structure determination efforts, reagent or antigen protein production and characterization, and/or antibody design, optimization, and characterization.
Collaborate and communicate with interdisciplinary teams, including structural biologists, protein chemists, in vitro pharmacologists, medicinal and computational chemists, and project management to advance pipeline projects.
Communicate protein production and characterization plans, priorities, results, and timelines to varied audiences.
Education & Competencies (Technical and Behavioral)
PhD degree in a scientific discipline (Structural Biology, Biophysics, Biochemistry/Enzymology, Protein Chemistry); MS with 6+ years or BS with 8+ years industry experience also considered; industry experience highly desirable.
Demonstrated track record of successful hands-on high-quality protein production (construct design, cloning, expression, purification, optimization, characterization) of protein reagents, antigens and/or antibodies or other biologics therapeutics for drug discovery teams.
Experience in protein production utilizing contract research organizations highly desirable.
Experience in design, expression and purification of membrane proteins and/or multi-protein complexes; knowledge of and/or experience in structural biology methodologies, biochemical and/or biophysical assays highly desirable.
Passion for learning and advancing protein production capabilities and drug discovery pipelines, including proactive investigation of new techniques and capabilities, software/hardware and innovative approaches.
Ability to work collaboratively in a fast-paced, matrixed environment with a proactive, collaborative mindset focused on therapeutic development.
Compensation and Benefits Takeda Compensation and Benefits Summary: We are committed to equitable pay and transparency in pay practices.
Location: Boston, MA
U.S. Base Salary Range $111,800.00 - $175,670.00
The actual base salary offered depends on qualifications, experience, and location, and will comply with applicable wage requirements. U.S. based employees may be eligible for incentives and benefits including medical, dental, vision, 401(k) with company match, disability and life insurance, tuition reimbursement, paid time off, holidays, and well-being programs.
EEO Statement Takeda is committed to creating a diverse workforce and providing equal employment opportunities to all employees and applicants without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or protected characteristics as defined by law.
Locations Boston, MA
Worker Type Employee
Worker Sub-Type Regular
Time Type Full time
Job Exempt Yes
It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment.
#J-18808-Ljbffr