ZipRecruiter
Principal Research Scientist I, Peptide Design
ZipRecruiter, North Chicago, Illinois, us, 60086
Overview
AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit www.abbvie.com. Follow @abbvie on X, Facebook, Instagram, YouTube, LinkedIn and TikTok.
Overview AbbVie seeks a knowledgeable, self-motivated, and creative scientist for cyclic peptide design in computational chemistry / drug discovery. The selected candidate will join our Computational Drug Discovery group within the Discovery Research organization. AbbVie has recently gained the capability to synthesize millions of custom cyclic peptide sequences in a “programmable” manner, and to individually characterize their interaction with a desired protein partner. The candidate will be expected to leverage this opportunity to computationally design novel cyclic peptides as an entry-point to this platform.
Responsibilities
Develop, implement, and deploy programs and computational solutions employing Machine Learning/Deep Learning and Cheminformatics
Implement, debug, and maintain computational tools in common programming languages (Python, etc.) and leverage cloud computing capabilities
Familiarity with modern deep learning architectures including GNN, CNN, RNN, Transformer, GCNN and MPNN, and machine learning paradigms such as generative models, GAN, and active learning
Qualifications
BS or equivalent education with typically 14+ years of experience; MS with typically 12+ years; PhD with typically 6+ years in the relevant discipline
Expertise in AI/ML-enabled molecular, pose, sequence design, and/or affinity prediction
Strong analytical and problem-solving skills with the ability to think critically and creatively, and to collaborate with internal experts to develop and optimize computational discovery infrastructure including cloud resources
Excellent ability to communicate clearly with colleagues and collaborators, including the ability to explain complex ideas to non-specialists
Strong programming skills in Python and experience with data science stack including NumPy, pandas, scikit-learn, and related scientific libraries
Additional Information
The compensation range described below is the range of possible base pay compensation the Company believes in good faith it will pay for this role at the time of this posting based on the job grade. Individual compensation paid within this range will depend on factors including location and may be more or less than the posted range. This range may be modified in the future.
We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance, and 401(k) to eligible employees.
This job is eligible to participate in our short-term incentive programs.
Note: No amount of pay is considered wages or compensation until earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains at the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.
AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.
US & Puerto Rico only - to learn more, visit abbvie.com/join-us/equal-employment-opportunity-employer.html
US & Puerto Rico applicants seeking a reasonable accommodation, learn more at abbvie.com/join-us/reasonable-accommodations.html
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Overview AbbVie seeks a knowledgeable, self-motivated, and creative scientist for cyclic peptide design in computational chemistry / drug discovery. The selected candidate will join our Computational Drug Discovery group within the Discovery Research organization. AbbVie has recently gained the capability to synthesize millions of custom cyclic peptide sequences in a “programmable” manner, and to individually characterize their interaction with a desired protein partner. The candidate will be expected to leverage this opportunity to computationally design novel cyclic peptides as an entry-point to this platform.
Responsibilities
Develop, implement, and deploy programs and computational solutions employing Machine Learning/Deep Learning and Cheminformatics
Implement, debug, and maintain computational tools in common programming languages (Python, etc.) and leverage cloud computing capabilities
Familiarity with modern deep learning architectures including GNN, CNN, RNN, Transformer, GCNN and MPNN, and machine learning paradigms such as generative models, GAN, and active learning
Qualifications
BS or equivalent education with typically 14+ years of experience; MS with typically 12+ years; PhD with typically 6+ years in the relevant discipline
Expertise in AI/ML-enabled molecular, pose, sequence design, and/or affinity prediction
Strong analytical and problem-solving skills with the ability to think critically and creatively, and to collaborate with internal experts to develop and optimize computational discovery infrastructure including cloud resources
Excellent ability to communicate clearly with colleagues and collaborators, including the ability to explain complex ideas to non-specialists
Strong programming skills in Python and experience with data science stack including NumPy, pandas, scikit-learn, and related scientific libraries
Additional Information
The compensation range described below is the range of possible base pay compensation the Company believes in good faith it will pay for this role at the time of this posting based on the job grade. Individual compensation paid within this range will depend on factors including location and may be more or less than the posted range. This range may be modified in the future.
We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance, and 401(k) to eligible employees.
This job is eligible to participate in our short-term incentive programs.
Note: No amount of pay is considered wages or compensation until earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains at the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.
AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.
US & Puerto Rico only - to learn more, visit abbvie.com/join-us/equal-employment-opportunity-employer.html
US & Puerto Rico applicants seeking a reasonable accommodation, learn more at abbvie.com/join-us/reasonable-accommodations.html
#J-18808-Ljbffr