insitro
Overview
insitro's mission is to use AI and machine learning to develop medicines for patients with diseases that have little to no effective treatment. insitro has built a target and biology discovery engine that combines high throughput, multimodal cellular phenotyping and perturbation data generation with novel machine learning methods. As Head of CellML, you will lead the team of ML scientists and engineers to generate biology insights from multiple data modalities at scale, spanning live and fixed microscopy imaging and diverse omics assays (scRNA, proteomics, spatial). You will co-develop the next generation of high-scale perturbation cellular assays and collaborate with therapeutic area leaders to design experiments and analyze data to advance our therapeutic pipeline. The role is hybrid and based in South San Francisco, requiring in-office presence at least three days per week.
Responsibilities
Work collaboratively with Drug Discovery leaders on the strategy for deployment of advanced ML to empower target discovery and biological insights, guiding experimental design that generates data enabling advanced ML methods
Lead and grow a team of machine learning scientists
Onboard and develop ML and bioinformatic methods for interpreting complex multi-modal perturbation data, including representation learning, contrastive approaches, disentanglement for interpretability, multi-modal embedding, and uncertainty modeling
Lead yearly and quarterly planning, set impactful goals, and align with cross-functional stakeholders
Engineer robust, reusable platform components in partnership with the software engineering team
Collaborate with platform biology and automation teams to advance platform capabilities, including development of new wet lab capabilities and ML methods, and generation of data designed for training ML models
Engage with corporate development and strategy teams to drive discussions with external partners and maximize value from platform technologies
About You
Technical skills:
Ph.D. in computer science, mathematics, biology, bioinformatics, or a related discipline, or equivalent practical experience
12+ years of real-world experience applying AI/ML to cellular data
In-depth knowledge of modern machine learning, including deep learning
Experience with imaging and omics modalities
Experience with cellular data in drug discovery is a plus
Peer-reviewed publications in high-quality conferences or journals
Experience in people management and leadership, including building and developing team members based on strategic company needs
Demonstrated ability to collaborate with life science colleagues to form research and therapeutic pipeline execution roadmaps
Demonstrated ability to lead a team of scientists and engineers to plan, execute and deliver a full ML solution for challenging problems: data sourcing/qualifying, model design, testing/benchmarking, and shipping robust code
Passion for providing better medicine to patients in need
Compensation & Benefits at insitro Our target starting salary for successful US-based applicants for this role is $315,000 - $360,000, with pay determined by skills, education, experience, market demand, and internal parity. The range may be adjusted in the future based on market data.
This role is eligible for participation in our Annual Performance Bonus Plan and Equity Incentive Plan, subject to plan terms and policies.
Insitro also provides the following benefits:
401(k) plan with employer matching
Medical, dental, and vision coverage, plus mental health support
Paid parental leave of at least 16 weeks for birth parents and 10 weeks for new parents
Budget for books and online courses for self-development
Support to attend professional conferences
New hire home office stipend
Monthly cell phone and internet stipend
Onsite cafe with daily lunch and breakfast for onsite/hybrid employees
Onsite fitness center access for onsite/hybrid employees
Free commuter bus and ferry network serving the South San Francisco HQ
Equal Opportunity insitro is an equal opportunity employer. All applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status.
We are committed to diversity, equity, and inclusion. We strive to build diverse teams and ensure an inclusive, growth-oriented environment with equitable practices throughout the interview process.
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insitro's mission is to use AI and machine learning to develop medicines for patients with diseases that have little to no effective treatment. insitro has built a target and biology discovery engine that combines high throughput, multimodal cellular phenotyping and perturbation data generation with novel machine learning methods. As Head of CellML, you will lead the team of ML scientists and engineers to generate biology insights from multiple data modalities at scale, spanning live and fixed microscopy imaging and diverse omics assays (scRNA, proteomics, spatial). You will co-develop the next generation of high-scale perturbation cellular assays and collaborate with therapeutic area leaders to design experiments and analyze data to advance our therapeutic pipeline. The role is hybrid and based in South San Francisco, requiring in-office presence at least three days per week.
Responsibilities
Work collaboratively with Drug Discovery leaders on the strategy for deployment of advanced ML to empower target discovery and biological insights, guiding experimental design that generates data enabling advanced ML methods
Lead and grow a team of machine learning scientists
Onboard and develop ML and bioinformatic methods for interpreting complex multi-modal perturbation data, including representation learning, contrastive approaches, disentanglement for interpretability, multi-modal embedding, and uncertainty modeling
Lead yearly and quarterly planning, set impactful goals, and align with cross-functional stakeholders
Engineer robust, reusable platform components in partnership with the software engineering team
Collaborate with platform biology and automation teams to advance platform capabilities, including development of new wet lab capabilities and ML methods, and generation of data designed for training ML models
Engage with corporate development and strategy teams to drive discussions with external partners and maximize value from platform technologies
About You
Technical skills:
Ph.D. in computer science, mathematics, biology, bioinformatics, or a related discipline, or equivalent practical experience
12+ years of real-world experience applying AI/ML to cellular data
In-depth knowledge of modern machine learning, including deep learning
Experience with imaging and omics modalities
Experience with cellular data in drug discovery is a plus
Peer-reviewed publications in high-quality conferences or journals
Experience in people management and leadership, including building and developing team members based on strategic company needs
Demonstrated ability to collaborate with life science colleagues to form research and therapeutic pipeline execution roadmaps
Demonstrated ability to lead a team of scientists and engineers to plan, execute and deliver a full ML solution for challenging problems: data sourcing/qualifying, model design, testing/benchmarking, and shipping robust code
Passion for providing better medicine to patients in need
Compensation & Benefits at insitro Our target starting salary for successful US-based applicants for this role is $315,000 - $360,000, with pay determined by skills, education, experience, market demand, and internal parity. The range may be adjusted in the future based on market data.
This role is eligible for participation in our Annual Performance Bonus Plan and Equity Incentive Plan, subject to plan terms and policies.
Insitro also provides the following benefits:
401(k) plan with employer matching
Medical, dental, and vision coverage, plus mental health support
Paid parental leave of at least 16 weeks for birth parents and 10 weeks for new parents
Budget for books and online courses for self-development
Support to attend professional conferences
New hire home office stipend
Monthly cell phone and internet stipend
Onsite cafe with daily lunch and breakfast for onsite/hybrid employees
Onsite fitness center access for onsite/hybrid employees
Free commuter bus and ferry network serving the South San Francisco HQ
Equal Opportunity insitro is an equal opportunity employer. All applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status.
We are committed to diversity, equity, and inclusion. We strive to build diverse teams and ensure an inclusive, growth-oriented environment with equitable practices throughout the interview process.
#J-18808-Ljbffr